G&T-seq: parallel sequencing of single-cell genomes and transcriptomes IC Macaulay, W Haerty, P Kumar, YI Li, TX Hu, MJ Teng, M Goolam, ... Nature methods 12 (6), 519-522, 2015 | 748 | 2015 |
APP metabolism regulates tau proteostasis in human cerebral cortex neurons S Moore, LDB Evans, T Andersson, E Portelius, J Smith, TB Dias, ... Cell reports 11 (5), 689-696, 2015 | 217 | 2015 |
Fully defined human pluripotent stem cell-derived microglia and tri-culture system model C3 production in Alzheimer’s disease SR Guttikonda, L Sikkema, J Tchieu, N Saurat, RM Walsh, O Harschnitz, ... Nature Neuroscience 24 (3), 343-354, 2021 | 131 | 2021 |
Developmental chromatin programs determine oncogenic competence in melanoma A Baggiolini, SJ Callahan, E Montal, JM Weiss, T Trieu, MM Tagore, ... Science 373 (6559), eabc1048, 2021 | 88 | 2021 |
Capturing the biology of disease severity in a PSC-based model of familial dysautonomia N Zeltner, F Fattahi, NC Dubois, N Saurat, F Lafaille, L Shang, B Zimmer, ... Nature medicine 22 (12), 1421-1427, 2016 | 62 | 2016 |
Dicer is required for neural stem cell multipotency and lineage progression during cerebral cortex development N Saurat, T Andersson, NA Vasistha, Z Molnár, FJ Livesey Neural development 8, 1-14, 2013 | 57 | 2013 |
HSP90-incorporating chaperome networks as biosensor for disease-related pathways in patient-specific midbrain dopamine neurons S Kishinevsky, T Wang, A Rodina, SY Chung, C Xu, J Philip, T Taldone, ... Nature communications 9 (1), 4345, 2018 | 42 | 2018 |
Cortical differentiation of human pluripotent cells for in vitro modeling of Alzheimer’s disease NG Saurat, FJ Livesey, S Moore Systems Biology of Alzheimer's Disease, 267-278, 2016 | 9 | 2016 |
TNF-NFkB-p53 axis restricts in vivo survival of hPSC-derived dopamine neuron TW Kim, SY Koo, M Riessland, H Cho, F Chaudhry, B Kolisnyk, MV Russo, ... bioRxiv, 2023.03. 29.534819, 2023 | 4 | 2023 |
Establishing RNAge to score cellular aging and rejuvenation paradigms and identify novel age-modulating compounds. C Zhang, N Saurat, D Cornacchia, SY Chung, T Skider, A Minotti, L Studer, ... Biorxiv: the Preprint Server for Biology, 2023 | 1 | 2023 |
Deep sequencing of proteotoxicity modifier genes uncovers a Presenilin-2/beta-amyloid-actin genetic risk module shared among alpha-synucleinopathies S Nazeen, X Wang, D Zielinski, I Lam, E Hallacli, P Xu, E Ethier, R Strom, ... bioRxiv, 2024.03. 03.583145, 2024 | | 2024 |
Identifying novel age-modulating compounds and quantifying cellular aging using novel computational framework for evaluating transcriptional age C Zhang, N Saurat, D Cornacchia, SY Chung, T Sikder, A Minotti, L Studer, ... bioRxiv, 2023.07. 03.547539, 2023 | | 2023 |
Cellular biology contributing to Alzheimer's disease pathology in human trisomy 21 cortical neurons NG Saurat University of Cambridge, 2015 | | 2015 |