| Red cell pyruvate kinase deficiency: molecular and clinical aspects A Zanella, E Fermo, P Bianchi, G Valentini British journal of haematology 130 (1), 11-25, 2005 | 257 | 2005 |
| The allosteric regulation of pyruvate kinase: a site-directed mutagenesis study G Valentini, L Chiarelli, R Fortin, ML Speranza, A Galizzi, A Mattevi Journal of Biological Chemistry 275 (24), 18145-18152, 2000 | 215 | 2000 |
| Pyruvate kinase deficiency: the genotype-phenotype association A Zanella, E Fermo, P Bianchi, LR Chiarelli, G Valentini Blood reviews 21 (4), 217-231, 2007 | 192 | 2007 |
| Structure and function of human erythrocyte pyruvate kinase: molecular basis of nonspherocytic hemolytic anemia G Valentini, LR Chiarelli, R Fortin, M Dolzan, A Galizzi, DJ Abraham, ... Journal of Biological Chemistry 277 (26), 23807-23814, 2002 | 165 | 2002 |
| Crystal structure of Escherichia coli pyruvate kinase type I: molecular basis of the allosteric transition A Mattevi, G Valentini, M Rizzi, ML Speranza, M Bolognesi, A Coda Structure 3 (7), 729-741, 1995 | 158 | 1995 |
| The allosteric regulation of pyruvate kinase A Mattevi, M Bolognesi, G Valentini FEBS letters 389 (1), 15-19, 1996 | 144 | 1996 |
| Expanding targets for a metabolic therapy of cancer: L-asparaginase D Covini, S Tardito, O Bussolati, L R Chiarelli, M V Pasquetto, R Digilio, ... Recent patents on anti-cancer drug discovery 7 (1), 4-13, 2012 | 120 | 2012 |
| Helicobacter pyloril-asparaginase: a promising chemotherapeutic agent D Cappelletti, LR Chiarelli, MV Pasquetto, S Stivala, G Valentini, C Scotti Biochemical and biophysical research communications 377 (4), 1222-1226, 2008 | 118 | 2008 |
| [27] AMP-and fructose 1, 6-bisphosphate-activated pyruvate kinases from Escherichia coli M Malcovati, G Valentini Methods in enzymology 90, 170-179, 1982 | 113 | 1982 |
| Molecular insights on pathogenic effects of mutations causing phosphoglycerate kinase deficiency LR Chiarelli, SM Morera, P Bianchi, E Fermo, A Zanella, A Galizzi, ... PLOS one 7 (2), e32065, 2012 | 76 | 2012 |
| Hereditary pyrimidine 5′‐nucleotidase deficiency: from genetics to clinical manifestations A Zanella, P Bianchi, E Fermo, G Valentini British journal of haematology 133 (2), 113-123, 2006 | 67 | 2006 |
| Cell-cycle inhibition by Helicobacter pylori L-asparaginase C Scotti, P Sommi, MV Pasquetto, D Cappelletti, S Stivala, P Mignosi, ... PloS one 5 (11), e13892, 2010 | 66 | 2010 |
| Analogous Mechanisms of Resistance to Benzothiazinones and Dinitrobenzamides in Mycobacterium smegmatis AL de Jesus Lopes Ribeiro, G Degiacomi, F Ewann, S Buroni, ... PloS one 6 (11), e26675, 2011 | 63 | 2011 |
| Inosine monophosphate dehydrogenase variability in renal transplant patients on long‐term mycophenolate mofetil therapy LR Chiarelli, M Molinaro, C Libetta, C Tinelli, L Cosmai, G Valentini, ... British journal of clinical pharmacology 69 (1), 38-50, 2010 | 59 | 2010 |
| Human erythrocyte pyruvate kinase: characterization of the recombinant enzyme and a mutant form (R510Q) causing nonspherocytic hemolytic anemia C Wang, LR Chiarelli, P Bianchi, DJ Abraham, A Galizzi, A Mattevi, ... Blood, The Journal of the American Society of Hematology 98 (10), 3113-3120, 2001 | 59 | 2001 |
| Chromosomal location of zein genes in Zea mays G Valentini, C Soave, E Ottaviano Heredity 42 (1), 33-40, 1979 | 57 | 1979 |
| Red cell pyruvate kinase deficiency: 17 new mutations of the PK‐LR gene E Fermo, P Bianchi, LR Chiarelli, F Cotton, C Vercellati, K Writzl, K Baker, ... British journal of haematology 129 (6), 839-846, 2005 | 43 | 2005 |
| Influence of fibronectin on the fibrillogenesis of type I and type III collagen ML Speranza, G Valentini, A Calligaro Collagen and related research 7 (2), 115-123, 1987 | 39 | 1987 |
| Two forms of pyruvate kinase in Escherichia coli a comparison of chemical and molecular properties G Valentini, P Iadarola, BL Somani, M Malcovati Biochimica et Biophysica Acta (BBA)-Enzymology 570 (2), 248-258, 1979 | 34 | 1979 |
| Erythrocyte adenylate kinase deficiency: characterization of recombinant mutant forms and relationship with nonspherocytic hemolytic anemia P Abrusci, LR Chiarelli, A Galizzi, E Fermo, P Bianchi, A Zanella, ... Experimental hematology 35 (8), 1182-1189, 2007 | 33 | 2007 |
