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Harkewal Singh
Harkewal Singh
Moderna Therapeutics
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Title
Cited by
Cited by
Year
The Biological Buffer Bicarbonate/CO2 Potentiates H2O2-Mediated Inactivation of Protein Tyrosine Phosphatases
H Zhou, H Singh, ZD Parsons, SM Lewis, S Bhattacharya, DR Seiner, ...
Journal of the American Chemical Society 133 (40), 15803-15805, 2011
742011
Structures of the PutA peripheral membrane flavoenzyme reveal a dynamic substrate-channeling tunnel and the quinone-binding site
H Singh, BW Arentson, DF Becker, JJ Tanner
Proceedings of the National Academy of Sciences 111 (9), 3389-3394, 2014
722014
Crystal structures and small-angle x-ray scattering analysis of UDP-galactopyranose mutase from the pathogenic fungus Aspergillus fumigatus
R Dhatwalia, H Singh, M Oppenheimer, DB Karr, JC Nix, P Sobrado, ...
Journal of Biological Chemistry 287 (12), 9041-9051, 2012
462012
Proline: Mother Nature's cryoprotectant applied to protein crystallography
TA Pemberton, BR Still, EM Christensen, H Singh, D Srivastava, ...
Acta Crystallographica Section D: Biological Crystallography 68 (8), 1010-1018, 2012
372012
Covalent allosteric inactivation of protein tyrosine phosphatase 1B (PTP1B) by an inhibitor–electrophile conjugate
P Punthasee, AR Laciak, AH Cummings, KV Ruddraraju, SM Lewis, ...
Biochemistry 56 (14), 2051-2060, 2017
332017
Crystal Structures of Trypanosoma cruzi UDP-Galactopyranose Mutase Implicate Flexibility of the Histidine Loop in Enzyme Activation
R Dhatwalia, H Singh, M Oppenheimer, P Sobrado, JJ Tanner
Biochemistry 51 (24), 4968-4979, 2012
332012
Identification of the NAD (P) H binding site of eukaryotic UDP-galactopyranose mutase
R Dhatwalia, H Singh, LM Solano, M Oppenheimer, RM Robinson, ...
Journal of the American Chemical Society 134 (43), 18132-18138, 2012
312012
Identification and characterization of a bacterial homolog of chloride intracellular channel (CLIC) protein
S Gururaja Rao, D Ponnalagu, S Sukur, H Singh, S Sanghvi, Y Mei, ...
Scientific reports 7 (1), 8500, 2017
252017
Inactivation of protein tyrosine phosphatases by dietary isothiocyanates
SM Lewis, Y Li, MJ Catalano, AR Laciak, H Singh, DR Seiner, TJ Reilly, ...
Bioorganic & Medicinal Chemistry Letters 25 (20), 4549-4552, 2015
212015
Crystal Structures of the histidine acid phosphatase from Francisella tularensis provide insight into substrate recognition
H Singh, RL Felts, JP Schuermann, TJ Reilly, JJ Tanner
Journal of molecular biology 394 (5), 893-904, 2009
202009
Biophysical investigation of type A PutAs reveals a conserved core oligomeric structure
DA Korasick, H Singh, TA Pemberton, M Luo, R Dhatwalia, JJ Tanner
The FEBS journal 284 (18), 3029-3049, 2017
142017
Recognition of nucleoside monophosphate substrates by Haemophilus influenzae class C acid phosphatase
H Singh, JP Schuermann, TJ Reilly, MJ Calcutt, JJ Tanner
Journal of molecular biology 404 (4), 639-649, 2010
132010
Crystal structure and tartrate inhibition of Legionella pneumophila histidine acid phosphatase
R Dhatwalia, H Singh, TJ Reilly, JJ Tanner
Archives of biochemistry and biophysics 585, 32-38, 2015
82015
Engineering a trifunctional proline utilization A chimaera by fusing a DNA-binding domain to a bifunctional PutA
BW Arentson, EL Hayes, W Zhu, H Singh, JJ Tanner, DF Becker
Bioscience reports 36 (6), e00413, 2016
72016
Docking studies of tau protein
H Singh, SS Marla, M Agarwal
IAENG International Journal of Computer Science 33 (1), 36-42, 2007
72007
Crystal structure and immunogenicity of the class C acid phosphatase from Pasteurella multocida
H Singh, TJ Malinski, TJ Reilly, MT Henzl, JJ Tanner
Archives of biochemistry and biophysics 509 (1), 76-81, 2011
42011
Enzymatic Conversion of RBCs by-N-Acetylgalactosaminidase from Spirosoma linguale
TJ Malinski, H Singh
Enzyme research 2019, 2019
32019
Structural basis of the inhibition of class C acid phosphatases by adenosine 5′‐phosphorothioate
H Singh, TJ Reilly, JJ Tanner
The FEBS journal 278 (22), 4374-4381, 2011
32011
Expression, purification and crystallization of an atypical class C acid phosphatase from Mycoplasma bovis
H Singh, TJ Reilly, MJ Calcutt, JJ Tanner
Acta Crystallographica Section F: Structural Biology and Crystallization …, 2011
32011
Expression, purification and crystallization of class C acid phosphatases from Francisella tularensis and Pasteurella multocida
H Singh, RL Felts, L Ma, TJ Malinski, MJ Calcutt, TJ Reilly, JJ Tanner
Acta Crystallographica Section F: Structural Biology and Crystallization …, 2009
32009
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