| WAF1, a potential mediator of p53 tumor suppression WS El-Deiry, T Tokino, VE Velculescu, DB Levy, R Parsons, JM Trent, ... Cell 75 (4), 817-825, 1993 | 10070 | 1993 |
| Cancer genome landscapes B Vogelstein, N Papadopoulos, VE Velculescu, S Zhou, LA Diaz, ... science 339 (6127), 1546-1558, 2013 | 6137 | 2013 |
| Lessons from hereditary colorectal cancer KW Kinzler, B Vogelstein Cell 87 (2), 159-170, 1996 | 5993 | 1996 |
| Serial analysis of gene expression VE Velculescu, L Zhang, B Vogelstein, KW Kinzler Science 270 (5235), 484-487, 1995 | 5789 | 1995 |
| PD-1 blockade in tumors with mismatch-repair deficiency DT Le, JN Uram, H Wang, BR Bartlett, H Kemberling, AD Eyring, ... New England Journal of Medicine 372 (26), 2509-2520, 2015 | 5665 | 2015 |
| An integrated genomic analysis of human glioblastoma multiforme DW Parsons, S Jones, X Zhang, JCH Lin, RJ Leary, P Angenendt, ... science 321 (5897), 1807-1812, 2008 | 5510 | 2008 |
| Identification of c-MYC as a target of the APC pathway TC He, AB Sparks, C Rago, H Hermeking, L Zawel, LT Da Costa, ... Science 281 (5382), 1509-1512, 1998 | 5344 | 1998 |
| The Metabolic and Molecular Z Chen, Y Pang, X Liu, X Wang, Z Deng, X Sun Bases of Inherited Disease; McGraw-Hill, Inc., Health Professions Division, 2001 | 5144* | 2001 |
| Cancer genes and the pathways they control B Vogelstein, KW Kinzler Nature medicine 10 (8), 789-799, 2004 | 4948 | 2004 |
| Genetic instabilities in human cancers C Lengauer, KW Kinzler, B Vogelstein Nature 396 (6712), 643-649, 1998 | 4813 | 1998 |
| A simplified system for generating recombinant adenoviruses TC He, S Zhou, LT Da Costa, J Yu, KW Kinzler, B Vogelstein Proceedings of the National Academy of Sciences 95 (5), 2509-2514, 1998 | 4675 | 1998 |
| IDH1 and IDH2 Mutations in Gliomas H Yan, DW Parsons, G Jin, R McLendon, BA Rasheed, W Yuan, I Kos, ... New England journal of medicine 360 (8), 765-773, 2009 | 4647 | 2009 |
| Activation of β-catenin-Tcf signaling in colon cancer by mutations in β-catenin or APC PJ Morin, AB Sparks, V Korinek, N Barker, H Clevers, B Vogelstein, ... Science 275 (5307), 1787-1790, 1997 | 4599 | 1997 |
| Core signaling pathways in human pancreatic cancers revealed by global genomic analyses S Jones, X Zhang, DW Parsons, JCH Lin, RJ Leary, P Angenendt, ... science 321 (5897), 1801-1806, 2008 | 3818 | 2008 |
| Constitutive transcriptional activation by a β-catenin-Tcf complex in APC−/− colon carcinoma V Korinek, N Barker, PJ Morin, D Van Wichen, R De Weger, KW Kinzler, ... Science 275 (5307), 1784-1787, 1997 | 3774 | 1997 |
| The consensus coding sequences of human breast and colorectal cancers T Sjöblom, S Jones, LD Wood, DW Parsons, J Lin, TD Barber, ... science 314 (5797), 268-274, 2006 | 3702 | 2006 |
| High frequency of mutations of the PIK3CA gene in human cancers Y Samuels, Z Wang, A Bardelli, N Silliman, J Ptak, S Szabo, H Yan, ... Science, 2004 | 3662 | 2004 |
| The genomic landscapes of human breast and colorectal cancers LD Wood, DW Parsons, S Jones, J Lin, T Sjöblom, RJ Leary, D Shen, ... Science 318 (5853), 1108-1113, 2007 | 3337 | 2007 |
| Clues to the pathogenesis of familial colorectal cancer LA Aaltonen, P Peltomaki, FS Leach, P Sistonen, L Pylkkanen, JP Mecklin, ... Science 260 (5109), 812-816, 1993 | 3293 | 1993 |
| Requirement for p53 and p21 to sustain G2 arrest after DNA damage F Bunz, A Dutriaux, C Lengauer, T Waldman, S Zhou, JP Brown, ... Science 282 (5393), 1497-1501, 1998 | 3199 | 1998 |
