Johanna Nyffeler (ORCiD 0000-0002-6155-9743)
Johanna Nyffeler (ORCiD 0000-0002-6155-9743)
ORISE grantee at U.S. EPA
Verified email at
Cited by
Cited by
Multiparameter toxicity assessment of novel DOPO-derived organophosphorus flame retardants
C Hirsch, B Striegl, S Mathes, C Adlhart, M Edelmann, E Bono, S Gaan, ...
Archives of toxicology 91 (1), 407-425, 2017
Design of a high-throughput human neural crest cell migration assay to indicate potential developmental toxicants
J Nyffeler, C Karreman, H Leisner, YJ Kim, G Lee, T Waldmann, M Leist
Alternatives to Animal Experimentation: ALTEX 34 (1), 75-94, 2017
Association study in siblings and case-controls of serotonin-and oxytocin-related genes with high functioning autism
J Nyffeler, S Walitza, E Bobrowski, R Gundelfinger, E Grünblatt
Journal of molecular psychiatry 2 (1), 1-9, 2014
Combination of multiple neural crest migration assays to identify environmental toxicants from a proof-of-concept chemical library
J Nyffeler, X Dolde, A Krebs, K Pinto-Gil, M Pastor, M Behl, T Waldmann, ...
Archives of toxicology 91 (11), 3613-3632, 2017
Bioactivity screening of environmental chemicals using imaging-based high-throughput phenotypic profiling
J Nyffeler, C Willis, R Lougee, A Richard, K Paul-Friedman, JA Harrill
Toxicology and Applied Pharmacology 389, 114876, 2020
Grouping of histone deacetylase inhibitors and other toxicants disturbing neural crest migration by transcriptional profiling
N Dreser, B Zimmer, C Dietz, E Sügis, G Pallocca, J Nyffeler, J Meisig, ...
Neurotoxicology 50, 56-70, 2015
Phenotypic Profiling of Reference Chemicals across Biologically Diverse Cell Types Using the Cell Painting Assay
C Willis, J Nyffeler, J Harrill
SLAS DISCOVERY: Advancing the Science of Drug Discovery 25 (7), 755-769, 2020
A structure–activity relationship linking non-planar PCBs to functional deficits of neural crest cells: new roles for connexins
J Nyffeler, P Chovancova, X Dolde, AK Holzer, V Purvanov, I Kindinger, ...
Archives of toxicology 92 (3), 1225-1247, 2018
Normalization of data for viability and relative cell function curves
A Krebs, J Nyffeler, J Rahnenführer, M Leist
Alternatives to Animal Experimentation: ALTEX 35 (2), 268-271, 2018
Determination of benchmark concentrations and their statistical uncertainty for cytotoxicity test data and functional in vitro assays
A Krebs, J Nyffeler, C Karreman, BZ Schmidt, F Kappenberg, J Mellert, ...
ALTEX-Alternatives to animal experimentation 37 (1), 155-163, 2020
Impairment of human neural crest cell migration by prolonged exposure to interferon-beta
G Pallocca, J Nyffeler, X Dolde, M Grinberg, G Gstraunthaler, T Waldmann, ...
Archives of toxicology 91 (10), 3385-3402, 2017
The synthetic peptide LyeTxI-b derived from Lycosa erythrognatha spider venom is cytotoxic to U-87 MG glioblastoma cells
MAL Abdel-Salam, J Carvalho-Tavares, KS Gomes, A Teixeira-Carvalho, ...
Amino acids 51 (3), 433-449, 2019
Stem cell microscopic image segmentation using supervised normalized cuts
X Huang, C Li, M Shen, K Shirahama, J Nyffeler, M Leist, M Grzegorzek, ...
2016 IEEE International Conference on Image Processing (ICIP), 4140-4144, 2016
Comparison of Approaches for Determining Bioactivity Hits from High-Dimensional Profiling Data
J Nyffeler, DE Haggard, C Willis, RW Setzer, R Judson, K Paul-Friedman, ...
SLAS DISCOVERY: Advancing the Science of Drug Discovery 26 (2), 292-308, 2021
Time and space-resolved quantification of plasma membrane sialylation for measurements of cell function and neurotoxicity
P Kranaster, C Karreman, JEGA Dold, A Krebs, M Funke, AK Holzer, ...
Archives of Toxicology 94 (2), 449-467, 2020
An expert-driven literature review of “negative” chemicals for developmental neurotoxicity (DNT) in vitro assay evaluation
MM Martin, NC Baker, WK Boyes, KE Carstens, ME Culbreth, ME Gilbert, ...
Neurotoxicology and Teratology, 107117, 2022
Corrigendum to normalization of data for viability and relative cell function curves
A Krebs, J Nyffeler, J Rahnenführer, M Leist
ALTEX-Alternatives to animal experimentation 36 (3), 505-505, 2019
Combining phenotypic profiling and targeted RNA-Seq reveals linkages between transcriptional perturbations and chemical effects on cell morphology: Retinoic acid as an example
J Nyffeler, C Willis, FR Harris, LW Taylor, R Judson, LJ Everett, JA Harrill
Toxicology and Applied Pharmacology 444, 116032, 2022
High-throughput phenotypic profiling within the NAMs-based, tiered hazard evaluation strategy at the United States Environmental Protection Agency
J Nyffeler, C Willis, M Culbreth, RE Brockway, LJ Everett, G Patlewicz, ...
Toxicology Letters 350, S61-S62, 2021
Strategic Use of High-Throughput Transcriptomics and Phenotypic Profiling Data in Support of Regulatory Decisions
J Harrill, L Everett, J Nyffeler, C Willis, R Brockway, KP Freidman, I Shah, ...
Toxicology Letters 350, S46-S47, 2021
The system can't perform the operation now. Try again later.
Articles 1–20