| Multi-target-directed ligands to combat neurodegenerative diseases A Cavalli, ML Bolognesi, A Minarini, M Rosini, V Tumiatti, M Recanatini, ... Journal of medicinal chemistry 51 (3), 347-372, 2008 | 1262 | 2008 |
| Rational approach to discover multipotent anti-Alzheimer drugs M Rosini, V Andrisano, M Bartolini, ML Bolognesi, P Hrelia, A Minarini, ... Journal of medicinal chemistry 48 (2), 360-363, 2005 | 291 | 2005 |
| Tacrine derivatives and Alzheimer's disease V Tumiatti, A Minarini, ML Bolognesi, A Milelli, M Rosini, C Melchiorre Current medicinal chemistry 17 (17), 1825-1838, 2010 | 269 | 2010 |
| Inhibition of acetylcholinesterase, β-amyloid aggregation, and NMDA receptors in Alzheimer’s disease: a promising direction for the multi-target-directed ligands gold rush M Rosini, E Simoni, M Bartolini, A Cavalli, L Ceccarini, N Pascu, ... Journal of medicinal chemistry 51 (15), 4381-4384, 2008 | 236 | 2008 |
| Oxidative stress in Alzheimer’s disease: are we connecting the dots? Miniperspective M Rosini, E Simoni, A Milelli, A Minarini, C Melchiorre Journal of medicinal chemistry 57 (7), 2821-2831, 2014 | 215 | 2014 |
| Alzheimer's disease: new approaches to drug discovery ML Bolognesi, R Matera, A Minarini, M Rosini, C Melchiorre Current opinion in chemical biology 13 (3), 303-308, 2009 | 173 | 2009 |
| Novel class of quinone-bearing polyamines as multi-target-directed ligands to combat Alzheimer's disease ML Bolognesi, R Banzi, M Bartolini, A Cavalli, A Tarozzi, V Andrisano, ... Journal of medicinal chemistry 50 (20), 4882-4897, 2007 | 171 | 2007 |
| Design, synthesis, and biological evaluation of conformationally restricted rivastigmine analogues ML Bolognesi, M Bartolini, A Cavalli, V Andrisano, M Rosini, A Minarini, ... Journal of medicinal chemistry 47 (24), 5945-5952, 2004 | 161 | 2004 |
| N-acetylcysteine in the treatment of psychiatric disorders: current status and future prospects A Minarini, S Ferrari, M Galletti, N Giambalvo, D Perrone, G Rioli, ... Expert opinion on drug metabolism & toxicology 13 (3), 279-292, 2017 | 132 | 2017 |
| Multi-target design strategies in the context of Alzheimer’s disease: acetylcholinesterase inhibition and NMDA receptor antagonism as the driving forces M Rosini, E Simoni, A Minarini, C Melchiorre Neurochemical research 39, 1914-1923, 2014 | 113 | 2014 |
| Multifunctional tacrine derivatives in Alzheimer's disease A Minarini, A Milelli, E Simoni, M Rosini, M Laura Bolognesi, C Marchetti, ... Current topics in medicinal chemistry 13 (15), 1771-1786, 2013 | 106 | 2013 |
| Cystamine-tacrine dimer: A new multi-target-directed ligand as potential therapeutic agent for Alzheimer’s disease treatment A Minarini, A Milelli, V Tumiatti, M Rosini, E Simoni, ML Bolognesi, ... Neuropharmacology, 2012 | 101 | 2012 |
| MTDL design strategy in the context of Alzheimer's disease: from lipocrine to memoquin and beyond ML Bolognesi, M Rosini, V Andrisano, M Bartolini, A Minarini, V Tumiatti, ... Current pharmaceutical design 15 (6), 601-613, 2009 | 92 | 2009 |
| Multitarget strategies in Alzheimer's disease: benefits and challenges on the road to therapeutics M Rosini, E Simoni, R Caporaso, A Minarini Future medicinal chemistry 8 (6), 697-711, 2016 | 91 | 2016 |
| Multitargeted drugs discovery: balancing anti-amyloid and anticholinesterase capacity in a single chemical entity ML Bolognesi, M Bartolini, A Tarozzi, F Morroni, F Lizzi, A Milelli, ... Bioorganic & medicinal chemistry letters 21 (9), 2655-2658, 2011 | 89 | 2011 |
| From dual binding site acetylcholinesterase inhibitors to multi-target-directed ligands (MTDLs): a step forward in the treatment of Alzheimer's disease ML Bolognesi, A Minarini, M Rosini, V Tumiatti, C Melchiorre Mini reviews in medicinal chemistry 8 (10), 960-967, 2008 | 83 | 2008 |
| Polyamines in drug discovery: from the universal template approach to the multitarget-directed ligand design strategy C Melchiorre, ML Bolognesi, A Minarini, M Rosini, V Tumiatti Journal of medicinal chemistry 53 (16), 5906-5914, 2010 | 78 | 2010 |
| Design, synthesis, and biological evaluation of substituted naphthalene imides and diimides as anticancer agent V Tumiatti, A Milelli, A Minarini, M Micco, A Gasperi Campani, L Roncuzzi, ... Journal of medicinal chemistry 52 (23), 7873-7877, 2009 | 71 | 2009 |
| Structure− activity relationships of acetylcholinesterase noncovalent inhibitors based on a polyamine backbone. 4. Further investigation on the inner spacer V Tumiatti, A Milelli, A Minarini, M Rosini, ML Bolognesi, M Micco, ... Journal of medicinal chemistry 51 (22), 7308-7312, 2008 | 71 | 2008 |
| Tumor vascular targeted liposomal-bortezomib minimizes side effects and increases therapeutic activity in human neuroblastoma G Zuccari, A Milelli, F Pastorino, M Loi, A Petretto, A Parise, C Marchetti, ... Journal of controlled release 211, 44-52, 2015 | 60 | 2015 |
