| The immune landscape of cancer V Thorsson, DL Gibbs, SD Brown, D Wolf, DS Bortone, THO Yang, ... Immunity 48 (4), 812-830. e14, 2018 | 1249 | 2018 |
| Comprehensive characterization of cancer driver genes and mutations MH Bailey, C Tokheim, E Porta-Pardo, S Sengupta, D Bertrand, ... Cell 173 (2), 371-385. e18, 2018 | 975 | 2018 |
| The systems biology graphical notation N Le Novere, M Hucka, H Mi, S Moodie, F Schreiber, A Sorokin, E Demir, ... Nature biotechnology 27 (8), 735-741, 2009 | 878 | 2009 |
| Oncogenic signaling pathways in the cancer genome atlas F Sanchez-Vega, M Mina, J Armenia, WK Chatila, A Luna, KC La, ... Cell 173 (2), 321-337. e10, 2018 | 856 | 2018 |
| Cell-of-origin patterns dominate the molecular classification of 10,000 tumors from 33 types of cancer KA Hoadley, C Yau, T Hinoue, DM Wolf, AJ Lazar, E Drill, R Shen, ... Cell 173 (2), 291-304. e6, 2018 | 763 | 2018 |
| An integrated TCGA pan-cancer clinical data resource to drive high-quality survival outcome analytics J Liu, T Lichtenberg, KA Hoadley, LM Poisson, AJ Lazar, AD Cherniack, ... Cell 173 (2), 400-416. e11, 2018 | 759 | 2018 |
| The BioPAX community standard for pathway data sharing E Demir, MP Cary, S Paley, K Fukuda, C Lemer, I Vastrik, G Wu, ... Nature biotechnology 28 (9), 935-942, 2010 | 637 | 2010 |
| Machine learning identifies stemness features associated with oncogenic dedifferentiation TM Malta, A Sokolov, AJ Gentles, T Burzykowski, L Poisson, JN Weinstein, ... Cell 173 (2), 338-354. e15, 2018 | 376 | 2018 |
| The cancer genome atlas comprehensive molecular characterization of renal cell carcinoma CJ Ricketts, AA De Cubas, H Fan, CC Smith, M Lang, E Reznik, R Bowlby, ... Cell reports 23 (1), 313-326. e5, 2018 | 327 | 2018 |
| An integrated metabolic atlas of clear cell renal cell carcinoma AA Hakimi, E Reznik, CH Lee, CJ Creighton, AR Brannon, A Luna, ... Cancer cell 29 (1), 104-116, 2016 | 327 | 2016 |
| Tumor immune microenvironment characterization in clear cell renal cell carcinoma identifies prognostic and immunotherapeutically relevant messenger RNA signatures Y Şenbabaoğlu, RS Gejman, AG Winer, M Liu, EM Van Allen, ... Genome biology 17 (1), 1-25, 2016 | 295 | 2016 |
| Pathogenic germline variants in 10,389 adult cancers K Huang, RJ Mashl, Y Wu, DI Ritter, J Wang, C Oh, M Paczkowska, ... Cell 173 (2), 355-370. e14, 2018 | 293 | 2018 |
| Genomic and molecular landscape of DNA damage repair deficiency across The Cancer Genome Atlas TA Knijnenburg, L Wang, MT Zimmermann, N Chambwe, GF Gao, ... Cell reports 23 (1), 239-254. e6, 2018 | 291 | 2018 |
| Genomic and functional approaches to understanding cancer aneuploidy AM Taylor, J Shih, G Ha, GF Gao, X Zhang, AC Berger, SE Schumacher, ... Cancer cell 33 (4), 676-689. e3, 2018 | 288 | 2018 |
| Spatial organization and molecular correlation of tumor-infiltrating lymphocytes using deep learning on pathology images J Saltz, R Gupta, L Hou, T Kurc, P Singh, V Nguyen, D Samaras, ... Cell reports 23 (1), 181-193. e7, 2018 | 284 | 2018 |
| Comprehensive analysis of alternative splicing across tumors from 8,705 patients A Kahles, KV Lehmann, NC Toussaint, M Hüser, SG Stark, ... Cancer cell 34 (2), 211-224. e6, 2018 | 260 | 2018 |
| Scalable open science approach for mutation calling of tumor exomes using multiple genomic pipelines K Ellrott, MH Bailey, G Saksena, KR Covington, C Kandoth, C Stewart, ... Cell systems 6 (3), 271-281. e7, 2018 | 247 | 2018 |
| lncRNA epigenetic landscape analysis identifies EPIC1 as an oncogenic lncRNA that interacts with MYC and promotes cell-cycle progression in cancer Z Wang, B Yang, M Zhang, W Guo, Z Wu, Y Wang, L Jia, S Li, ... Cancer cell 33 (4), 706-720. e9, 2018 | 228 | 2018 |
| A comprehensive pan-cancer molecular study of gynecologic and breast cancers AC Berger, A Korkut, RS Kanchi, AM Hegde, W Lenoir, W Liu, Y Liu, ... Cancer cell 33 (4), 690-705. e9, 2018 | 222 | 2018 |
| Driver fusions and their implications in the development and treatment of human cancers Q Gao, WW Liang, SM Foltz, G Mutharasu, RG Jayasinghe, S Cao, ... Cell reports 23 (1), 227-238. e3, 2018 | 205 | 2018 |
