Circulating miR-375 as a biomarker of β-cell death and diabetes in mice S Erener, M Mojibian, JK Fox, HC Denroche, TJ Kieffer Endocrinology 154 (2), 603-608, 2013 | 214 | 2013 |
The role of leptin in glucose homeostasis HC Denroche, FK Huynh, TJ Kieffer Journal of diabetes investigation 3 (2), 115-129, 2012 | 182 | 2012 |
IL-33 reverses an obesity-induced deficit in visceral adipose tissue ST2+ T regulatory cells and ameliorates adipose tissue inflammation and insulin resistance JM Han, D Wu, HC Denroche, Y Yao, CB Verchere, MK Levings The Journal of Immunology 194 (10), 4777-4783, 2015 | 177 | 2015 |
Leptin therapy reverses hyperglycemia in mice with streptozotocin-induced diabetes, independent of hepatic leptin signaling HC Denroche, J Levi, RD Wideman, RM Sequeira, FK Huynh, SD Covey, ... Diabetes 60 (5), 1414-1423, 2011 | 133 | 2011 |
Disruption of hepatic leptin signaling protects mice from age-and diet-related glucose intolerance FK Huynh, J Levi, HC Denroche, SL Gray, PJ Voshol, UH Neumann, ... Diabetes 59 (12), 3032-3040, 2010 | 89 | 2010 |
IL-1 mediates amyloid-associated islet dysfunction and inflammation in human islet amyloid polypeptide transgenic mice CY Westwell-Roper, CA Chehroudi, HC Denroche, JA Courtade, ... Diabetologia 58, 575-585, 2015 | 74 | 2015 |
IAPP and type 1 diabetes: implications for immunity, metabolism and islet transplants HC Denroche, CB Verchere Journal of molecular endocrinology 60 (2), R57-R75, 2018 | 48 | 2018 |
Differential activation of innate immune pathways by distinct islet amyloid polypeptide (IAPP) aggregates C Westwell-Roper, HC Denroche, JA Ehses, CB Verchere Journal of Biological Chemistry 291 (17), 8908-8917, 2016 | 47 | 2016 |
Amyloid formation in human islets is enhanced by heparin and inhibited by heparinase KJ Potter, I Werner, HC Denroche, J Montane, A Plesner, Y Chen, D Lei, ... American journal of transplantation 15 (6), 1519-1530, 2015 | 36 | 2015 |
Hepatic leptin signalling and subdiaphragmatic vagal efferents are not required for leptin-induced increases of plasma IGF binding protein-2 (IGFBP-2) in ob/ob mice J Levi, FK Huynh, HC Denroche, UH Neumann, MM Glavas, SD Covey, ... Diabetologia 55, 752-762, 2012 | 32 | 2012 |
Leptin induces fasting hypoglycaemia in a mouse model of diabetes through the depletion of glycerol HC Denroche, MM Kwon, WL Quong, UH Neumann, JE Kulpa, ... Diabetologia 58, 1100-1108, 2015 | 30 | 2015 |
Insulin knockout mice have extended survival but volatile blood glucose levels on leptin therapy UH Neumann, HC Denroche, M Mojibian, SD Covey, TJ Kieffer Endocrinology 157 (3), 1007-1012, 2016 | 29 | 2016 |
Partial ablation of leptin signaling in mouse pancreatic α-cells does not alter either glucose or lipid homeostasis E Tudurí, HC Denroche, JA Kara, A Asadi, JK Fox, TJ Kieffer American Journal of Physiology-Endocrinology and Metabolism 306 (7), E748-E755, 2014 | 21 | 2014 |
Disrupted leptin signaling in the lateral hypothalamus and ventral premammillary nucleus alters insulin and glucagon secretion and protects against diet-induced obesity HC Denroche, MM Glavas, E Tudurí, S Karunakaran, WL Quong, ... Endocrinology 157 (7), 2671-2685, 2016 | 19 | 2016 |
Leptin administration enhances islet transplant performance in diabetic mice HC Denroche, WL Quong, JE Bruin, E Tudurí, A Asadi, MM Glavas, ... Diabetes 62 (8), 2738-2746, 2013 | 19 | 2013 |
The role of autonomic efferents and uncoupling protein 1 in the glucose-lowering effect of leptin therapy HC Denroche, MM Kwon, MM Glavas, E Tudurí, M Philippe, WL Quong, ... Molecular metabolism 5 (8), 716-724, 2016 | 17 | 2016 |
AAV8 Ins1-Cre can produce efficient β-cell recombination but requires consideration of off-target effects A Ramzy, E Tudurí, MM Glavas, RK Baker, M Mojibian, JK Fox, ... Scientific Reports 10 (1), 10518, 2020 | 16 | 2020 |
T cells accumulate in non-diabetic islets during ageing HC Denroche, S Miard, S Sallé-Lefort, F Picard, CB Verchere Immunity & Ageing 18, 1-13, 2021 | 10 | 2021 |
Impaired Ca2+ Signaling in β-Cells Lacking Leptin Receptors by Cre-loxP Recombination E Tudurí, JE Bruin, HC Denroche, JK Fox, JD Johnson, TJ Kieffer PLoS One 8 (8), e71075, 2013 | 10 | 2013 |
When beta cells talk back HC Denroche, D Nackiewicz, CB Verchere Diabetologia 61 (1), 39-42, 2018 | 8 | 2018 |