| Sequence saturation mutagenesis (SeSaM): a novel method for directed evolution TS Wong, KL Tee, B Hauer, U Schwaneberg Nucleic acids research 32 (3), e26-e26, 2004 | 289 | 2004 |
| Single-step fermentative production of the cholesterol-lowering drug pravastatin via reprogramming of Penicillium chrysogenum KJ McLean, M Hans, B Meijrink, WB van Scheppingen, A Vollebregt, ... Proceedings of the National Academy of Sciences 112 (9), 2847-2852, 2015 | 157 | 2015 |
| Polishing the craft of genetic diversity creation in directed evolution KL Tee, TS Wong Biotechnology advances 31 (8), 1707-1721, 2013 | 135 | 2013 |
| Directed evolution of oxygenases: screening systems, success stories and challenges K Lan Tee, U Schwaneberg Combinatorial chemistry & high throughput screening 10 (3), 197-217, 2007 | 101 | 2007 |
| Design and application of genetically-encoded malonyl-CoA biosensors for metabolic engineering of microbial cell factories AO Johnson, M Gonzalez-Villanueva, L Wong, A Steinbüchel, KL Tee, ... Metabolic engineering 44, 253-264, 2017 | 100 | 2017 |
| A screening system for the directed evolution of epoxygenases: importance of position 184 in P450 BM3 for stereoselective styrene epoxidation KL Tee, U Schwaneberg Angewandte Chemie International Edition 45 (32), 5380-5383, 2006 | 90 | 2006 |
| Catalytic determinants of alkene production by the cytochrome P450 peroxygenase OleTJE S Matthews, JD Belcher, KL Tee, HM Girvan, KJ McLean, SEJ Rigby, ... Journal of Biological Chemistry 292 (12), 5128-5143, 2017 | 82 | 2017 |
| Biological diversity of cytochrome P450 redox partner systems KJ McLean, D Luciakova, J Belcher, KL Tee, AW Munro Monooxygenase, Peroxidase and Peroxygenase Properties and Mechanisms of …, 2015 | 72 | 2015 |
| Production of alkenes and novel secondary products by P450 OleTJE using novel H2O2‐generating fusion protein systems S Matthews, KL Tee, NJ Rattray, KJ McLean, D Leys, DA Parker, ... FEBS letters 591 (5), 737-750, 2017 | 64 | 2017 |
| Ionic liquid effects on the activity of monooxygenase P450 BM-3 KL Tee, D Roccatano, S Stolte, J Arning, B Jastorff, U Schwaneberg Green Chemistry 10 (1), 117-123, 2008 | 61 | 2008 |
| Transversion‐enriched sequence saturation mutagenesis (SeSaM‐Tv+): A random mutagenesis method with consecutive nucleotide exchanges that complements … T Seng Wong, D Roccatano, D Loakes, KL Tee, A Schenk, B Hauer, ... Biotechnology Journal: Healthcare Nutrition Technology 3 (1), 74-82, 2008 | 60 | 2008 |
| Directed evolution of an antitumor drug (arginine deiminase PpADI) for increased activity at physiological pH L Zhu, KL Tee, D Roccatano, B Sonmez, Y Ni, ZH Sun, U Schwaneberg ChemBioChem 11 (5), 691-697, 2010 | 53 | 2010 |
| An Engineered Constitutive Promoter Set with Broad Activity Range for Cupriavidus necator H16 AO Johnson, M Gonzalez-Villanueva, KL Tee, TS Wong ACS Synthetic Biology 7 (8), 1918-1928, 2018 | 46 | 2018 |
| Production of trimeric SARS‐CoV‐2 spike protein by CHO cells for serological COVID‐19 testing YB Johari, SRP Jaffé, JM Scarrott, AO Johnson, T Mozzanino, TH Pohle, ... Biotechnology and bioengineering 118 (2), 1013-1021, 2021 | 44 | 2021 |
| Monooxygenaze, Peroxidaze and Peroxygenase Properties and Mechanisims of Cytochrome P450 M Akbar, AI Archakov, K Auclair, SM Bandera, J Belcher, T Bulko, ... Springer International Publishing, 2015 | 44 | 2015 |
| Sequence saturation mutagenesis with tunable mutation frequencies TS Wong, KL Tee, B Hauer, U Schwaneberg Analytical biochemistry 1 (341), 187-189, 2005 | 42 | 2005 |
| The role of active-site Phe87 in modulating the organic co-solvent tolerance of cytochrome P450 BM3 monooxygenase J Kuper, KL Tee, M Wilmanns, D Roccatano, U Schwaneberg, TS Wong Acta Crystallographica Section F: Structural Biology and Crystallization …, 2012 | 37 | 2012 |
| An Efficient Transformation Method for the Bioplastic‐Producing “Knallgas” Bacterium Ralstonia eutropha H16 KL Tee, J Grinham, AM Othusitse, M González‐Villanueva, AO Johnson, ... Biotechnology Journal 12 (11), 1700081, 2017 | 30 | 2017 |
| Sequence analysis TS Wong, KL Tee, TS Wong, KL Tee A Practical Guide to Protein Engineering, 11-27, 2020 | 24 | 2020 |
| Accelerated directed evolution of dye-decolorizing peroxidase using a bacterial extracellular protein secretion system (BENNY) AHA Alessa, KL Tee, D Gonzalez-Perez, HEM Omar Ali, CA Evans, ... Bioresources and Bioprocessing 6, 1-12, 2019 | 24 | 2019 |
