A synthetic optogenetic transcription device enhances blood-glucose homeostasis in mice H Ye, MDE Baba, RW Peng, M Fussenegger Science 332 (6037), 1565-1568, 2011 | 517 | 2011 |
Sly1 protein bound to Golgi syntaxin Sed5p allows assembly and contributes to specificity of SNARE fusion complexes R Peng, D Gallwitz The Journal of cell biology 157 (4), 645-655, 2002 | 213 | 2002 |
Evidence for overlapping and distinct functions in protein transport of coat protein Sec24p family members R Peng, A De Antoni, D Gallwitz Journal of Biological Chemistry 275 (15), 11521-11528, 2000 | 140 | 2000 |
New horizons in KRAS-mutant lung cancer: dawn after darkness H Yang, SQ Liang, RA Schmid, RW Peng Frontiers in oncology 9, 482949, 2019 | 130 | 2019 |
A microfluidic platform for chemoresistive testing of multicellular pleural cancer spheroids. GOT Ruppen J, Cortes-Dericks L, Marconi E, Karoubi G, Schmid RA, Peng R ... Lab on a Chip 14 (6), 198-205, 2014 | 130* | 2014 |
Multiple SNARE interactions of an SM protein: Sed5p/Sly1p binding is dispensable for transport R Peng, D Gallwitz The EMBO journal 23 (20), 3939-3949, 2004 | 114 | 2004 |
Molecular engineering of exocytic vesicle traffic enhances the productivity of Chinese hamster ovary cells RW Peng, M Fussenegger Biotechnology and bioengineering 102 (4), 1170-1181, 2009 | 99 | 2009 |
Blocking the epithelial-to-mesenchymal transition pathway abrogates resistance to anti-folate chemotherapy in lung cancer PRW Liang SQ, Marti TM, Dorn P, Froment L, Hall SR, Berezowska S, Kocher G ... Cell Death & Disease 6, e1824, 2015 | 90 | 2015 |
Specific interaction of the yeast cis-Golgi syntaxin Sed5p and the coat protein complex II component Sec24p of endoplasmic reticulum-derived transport vesicles R Peng, R Grabowski, A De Antoni, D Gallwitz Proceedings of the National Academy of Sciences 96 (7), 3751-3756, 1999 | 78 | 1999 |
Differential effect of exocytic SNAREs on the production of recombinant proteins in mammalian cells RW Peng, E Abellan, M Fussenegger Biotechnology and bioengineering 108 (3), 611-620, 2011 | 72 | 2011 |
The vesicle-trafficking protein munc18b increases the secretory capacity of mammalian cells RW Peng, C Guetg, M Tigges, M Fussenegger Metabolic engineering 12 (1), 18-25, 2010 | 57 | 2010 |
Targeting histone deacetylase enhances the therapeutic effect of Erastin-induced ferroptosis in EGFR-activating mutant lung adenocarcinoma T Zhang, B Sun, C Zhong, K Xu, Z Wang, P Hofman, T Nagano, A Legras, ... Translational lung cancer research 10 (4), 1857, 2021 | 51 | 2021 |
HSP90/AXL/eIF4E-regulated unfolded protein response as an acquired vulnerability in drug-resistant KRAS-mutant lung cancer H Yang, SQ Liang, D Xu, Z Yang, TM Marti, Y Gao, GJ Kocher, H Zhao, ... Oncogenesis 8 (9), 45, 2019 | 49 | 2019 |
mTOR mediates a mechanism of resistance to chemotherapy and defines a rational combination strategy to treat KRAS-mutant lung cancer SQ Liang, ED Bührer, S Berezowska, TM Marti, D Xu, L Froment, H Yang, ... Oncogene 38 (5), 622-636, 2019 | 45 | 2019 |
Tumor initiation capacity and therapy resistance are differential features of EMT-related subpopulations in the NSCLC cell line A549 CC Tièche, Y Gao, ED Bührer, N Hobi, SA Berezowska, K Wyler, ... Neoplasia 21 (2), 185-196, 2019 | 44 | 2019 |
Structure-based functional analysis reveals a role for the SM protein Sly1p in retrograde transport to the endoplasmic reticulum Y Li, D Gallwitz, R Peng Molecular biology of the cell 16 (9), 3951-3962, 2005 | 42 | 2005 |
Increased PD-L1 expression and IL-6 secretion characterize human lung tumor-derived perivascular-like cells that promote vascular leakage in a perfusable microvasculature model CA Bichsel, L Wang, L Froment, S Berezowska, S Müller, P Dorn, ... Scientific reports 7 (1), 10636, 2017 | 38 | 2017 |
Prolonged pemetrexed pretreatment augments persistence of cisplatin-induced DNA damage and eliminates resistant lung cancer stem-like cells associated with EMT. MTM Tièche CC, Peng RW, Dorn P, Froment L, Schmid RA BMC Cancer 16 (1), 125, 2016 | 38* | 2016 |
Biomarker-guided targeted and immunotherapies in malignant pleural mesothelioma H Yang, D Xu, RA Schmid, RW Peng Therapeutic advances in medical oncology 12, 1758835920971421, 2020 | 33 | 2020 |
ACSL3–PAI-1 signaling axis mediates tumor-stroma cross-talk promoting pancreatic cancer progression M Rossi Sebastiano, C Pozzato, M Saliakoura, Z Yang, RW Peng, M Galiè, ... Science advances 6 (44), eabb9200, 2020 | 33 | 2020 |