F Ann Ran
F Ann Ran
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Cited by
Cited by
Multiplex genome engineering using CRISPR/Cas systems
L Cong, FA Ran, D Cox, S Lin, R Barretto, N Habib, PD Hsu, X Wu, ...
Science 339 (6121), 819-823, 2013
Genome engineering using the CRISPR-Cas9 system
F Ran, PD Hsu, J Wright, V Agarwala, DA Scott, F Zhang
Nature protocols 8 (11), 2281-2308, 2013
DNA targeting specificity of RNA-guided Cas9 nucleases
PD Hsu, DA Scott, JA Weinstein, FA Ran, S Konermann, V Agarwala, Y Li, ...
Nature biotechnology 31 (9), 827-832, 2013
Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity
FA Ran, PD Hsu, CY Lin, JS Gootenberg, S Konermann, AE Trevino, ...
Cell 154 (6), 1380-1389, 2013
In vivo genome editing using Staphylococcus aureus Cas9
FA Ran, L Cong, WX Yan, DA Scott, JS Gootenberg, AJ Kriz, B Zetsche, ...
Nature 520 (7546), 186-191, 2015
Crystal structure of Cas9 in complex with guide RNA and target DNA
H Nishimasu, FA Ran, PD Hsu, S Konermann, SI Shehata, N Dohmae, ...
Cell 156 (5), 935-949, 2014
In vivo genome editing improves muscle function in a mouse model of Duchenne muscular dystrophy
CE Nelson, CH Hakim, DG Ousterout, PI Thakore, EA Moreb, RMC Rivera, ...
Science 351 (6271), 403-407, 2016
In vivo gene editing in dystrophic mouse muscle and muscle stem cells
M Tabebordbar, K Zhu, JKW Cheng, WL Chew, JJ Widrick, WX Yan, ...
Science 351 (6271), 407-411, 2016
CRISPR-Cas nickase systems, methods and compositions for sequence manipulation in eukaryotes
L Cong, F Zhang
US Patent 8,932,814, 2015
Common genetic variants modulate pathogen-sensing responses in human dendritic cells
MN Lee, C Ye, AC Villani, T Raj, W Li, TM Eisenhaure, SH Imboywa, ...
Science 343 (6175), 1246980, 2014
Crystal structure of Staphylococcus aureus Cas9
H Nishimasu, L Cong, WX Yan, FA Ran, B Zetsche, Y Li, A Kurabayashi, ...
Cell 162 (5), 1113-1126, 2015
Crystal structure of the minimal Cas9 from Campylobacter jejuni reveals the molecular diversity in the CRISPR-Cas9 systems
M Yamada, Y Watanabe, JS Gootenberg, H Hirano, FA Ran, T Nakane, ...
Molecular cell 65 (6), 1109-1121. e3, 2017
RNA-guided genome editing of mammalian cells
NK Pyzocha, FA Ran, PD Hsu, F Zhang
Gene Correction: Methods and Protocols, 269-277, 2014
In Vivo Genome Engineering With AAV Vector Carrying CRISPR-Cas9 System
L Cong, WX Yan, F Ran, B Zetsche, F Zhang
Molecular Therapy 22, S214-S214, 2014
Adaptation of CRISPR nucleases for eukaryotic applications
FA Ran
Analytical biochemistry 532, 90-94, 2017
CRISPR-Cas: Development and applications for mammalian genome editing
FA Ran
Harvard University, 2014
482. Local and Systemic Gene Editing in a Mouse Model of Duchenne Muscular Dystrophy
C Nelson, M Gemberling, CH Hakim, DG Ousterout, PI Thakore, ...
Molecular Therapy 24, S191, 2016
CRISPR/Cas9: tools and applications for eukaryotic genome editing
FA Ran
NABC, 2014
Protocol Exchange
E Owusu-Ansah, A Yavari, U Banerjee
DOI, 2008
397. Correction of the Dystrophin Gene By the CRISPR/Cas9 System in a Mouse Model of Muscular Dystrophy
CE Nelson, DG Ousterout, JN Robinson-Hamm, EA Moreb, ...
Molecular Therapy 23, S157-S158, 2015
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