|DNA methylation-based classification of central nervous system tumours|
D Capper, DTW Jones, M Sill, V Hovestadt, D Schrimpf, D Sturm, ...
Nature 555 (7697), 469-474, 2018
|The whole-genome landscape of medulloblastoma subtypes|
PA Northcott, I Buchhalter, AS Morrissy, V Hovestadt, J Weischenfeldt, ...
Nature 547 (7663), 311-317, 2017
|Modulation of TET2 expression and 5-methylcytosine oxidation by the CXXC domain protein IDAX|
M Ko, J An, HS Bandukwala, L Chavez, T Äijö, WA Pastor, MF Segal, H Li, ...
Nature 497 (7447), 122-126, 2013
|The landscape of genomic alterations across childhood cancers|
SN Gröbner, BC Worst, J Weischenfeldt, I Buchhalter, K Kleinheinz, ...
Nature 555 (7696), 321-327, 2018
|Atypical teratoid/rhabdoid tumors are comprised of three epigenetic subgroups with distinct enhancer landscapes|
PD Johann, S Erkek, M Zapatka, K Kerl, I Buchhalter, V Hovestadt, ...
Cancer cell 29 (3), 379-393, 2016
|Large conserved domains of low DNA methylation maintained by Dnmt3a|
M Jeong, D Sun, M Luo, Y Huang, GA Challen, B Rodriguez, X Zhang, ...
Nature genetics 46 (1), 17, 2014
|Distinct roles of the methylcytosine oxidases Tet1 and Tet2 in mouse embryonic stem cells|
Y Huang, L Chavez, X Chang, X Wang, WA Pastor, J Kang, ...
Proceedings of the National Academy of Sciences 111 (4), 1361-1366, 2014
|Active medulloblastoma enhancers reveal subgroup-specific cellular origins|
CY Lin, S Erkek, Y Tong, L Yin, AJ Federation, M Zapatka, P Haldipur, ...
Nature 530 (7588), 57-62, 2016
|MEDIPS: genome-wide differential coverage analysis of sequencing data derived from DNA enrichment experiments|
M Lienhard, C Grimm, M Morkel, R Herwig, L Chavez
Bioinformatics 30 (2), 284-286, 2014
|DNA methylation-based classification and grading system for meningioma: a multicentre, retrospective analysis|
F Sahm, D Schrimpf, D Stichel, DTW Jones, T Hielscher, S Schefzyk, ...
The lancet oncology 18 (5), 682-694, 2017
|Computational analysis of genome-wide DNA methylation during the differentiation of human embryonic stem cells along the endodermal lineage|
L Chavez, J Jozefczuk, C Grimm, J Dietrich, B Timmermann, H Lehrach, ...
Genome research 20 (10), 1441-1450, 2010
|Epigenomic analysis of primary human T cells reveals enhancers associated with TH2 memory cell differentiation and asthma susceptibility|
G Seumois, L Chavez, A Gerasimova, M Lienhard, N Omran, L Kalinke, ...
Nature immunology 15 (8), 777-788, 2014
|Innate-like functions of natural killer T cell subsets result from highly divergent gene programs|
I Engel, G Seumois, L Chavez, D Samaniego-Castruita, B White, ...
Nature immunology 17 (6), 728-739, 2016
|PET-guided treatment in patients with advanced-stage Hodgkin's lymphoma (HD18): final results of an open-label, international, randomised phase 3 trial by the German Hodgkin …|
P Borchmann, H Goergen, C Kobe, A Lohri, R Greil, DA Eichenauer, ...
The Lancet 390 (10114), 2790-2802, 2017
|The histone deacetylase SIRT6 controls embryonic stem cell fate via TET-mediated production of 5-hydroxymethylcytosine|
JP Etchegaray, L Chavez, Y Huang, KN Ross, J Choi, B Martinez-Pastor, ...
Nature cell biology 17 (5), 545-557, 2015
|A data integration approach to mapping OCT4 gene regulatory networks operative in embryonic stem cells and embryonal carcinoma cells|
M Jung, H Peterson, L Chavez, P Kahlem, H Lehrach, J Vilo, J Adjaye
PloS one 5 (5), 2010
|Dynamic Changes in Chromatin Accessibility Occur in CD8+ T Cells Responding to Viral Infection|
JP Scott-Browne, IF López-Moyado, S Trifari, V Wong, L Chavez, A Rao, ...
Immunity 45 (6), 1327-1340, 2016
|Comparative analysis of human embryonic stem cell and induced pluripotent stem cell-derived hepatocyte-like cells reveals current drawbacks and possible strategies for improved …|
J Jozefczuk, A Prigione, L Chavez, J Adjaye
Stem cells and development 20 (7), 1259-1275, 2011
|Acute loss of TET function results in aggressive myeloid cancer in mice|
J An, E González-Avalos, A Chawla, M Jeong, IF López-Moyado, W Li, ...
Nature communications 6 (1), 1-14, 2015
|Spectrum and prevalence of genetic predisposition in medulloblastoma: a retrospective genetic study and prospective validation in a clinical trial cohort|
SM Waszak, PA Northcott, I Buchhalter, GW Robinson, C Sutter, ...
The Lancet Oncology 19 (6), 785-798, 2018