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Milos Lazic
Milos Lazic
Senior Scientist, 858 Therapeutics
Bestätigte E-Mail-Adresse bei 8five8tx.com
Titel
Zitiert von
Zitiert von
Jahr
Lipid-induced toxicity stimulates hepatocytes to release angiogenic microparticles that require Vanin-1 for uptake by endothelial cells
D Povero, A Eguchi, IR Niesman, N Andronikou, X de Mollerat du Jeu, ...
Science signaling 6 (296), ra88-ra88, 2013
2232013
Transient prenatal androgen exposure produces metabolic syndrome in adult female rats
M Demissie, M Lazic, EM Foecking, F Aird, A Dunaif, JE Levine
American Journal of Physiology-Endocrinology and Metabolism 295 (2), E262-E268, 2008
1752008
Genetic rescue of nonclassical ERα signaling normalizes energy balance in obese Erα-null mutant mice
CJ Park, Z Zhao, C Glidewell-Kenney, M Lazic, P Chambon, A Krust, ...
The Journal of clinical investigation 121 (2), 604-612, 2011
1702011
Circulating adipocyte-derived extracellular vesicles are novel markers of metabolic stress
A Eguchi, M Lazic, AM Armando, SA Phillips, R Katebian, S Maraka, ...
Journal of molecular medicine 94, 1241-1253, 2016
1442016
Microparticles release by adipocytes act as “find-me” signals to promote macrophage migration
A Eguchi, A Mulya, M Lazic, D Radhakrishnan, MP Berk, D Povero, ...
PloS one 10 (4), e0123110, 2015
1012015
Reduced dietary omega-6 to omega-3 fatty acid ratio and 12/15-lipoxygenase deficiency are protective against chronic high fat diet-induced steatohepatitis
M Lazic, ME Inzaugarat, D Povero, IC Zhao, M Chen, M Nalbandian, ...
PloS one 9 (9), e107658, 2014
692014
Redox nanoparticles as a novel treatment approach for inflammation and fibrosis associated with nonalcoholic steatohepatitis
A Eguchi, T Yoshitomi, M Lazic, CD Johnson, LB Vong, A Wree, D Povero, ...
Nanomedicine 10 (17), 2697-2708, 2015
492015
Prenatal androgen treatment alters body composition and glucose homeostasis in male rats
M Lazic, F Aird, JE Levine, A Dunaif
Journal of endocrinology 208 (3), 293, 2011
382011
Overcoming Preclinical Safety Obstacles to Discover (S)-N-((1, 2, 3, 5, 6, 7-Hexahydro-s-indacen-4-yl) carbamoyl)-6-(methylamino)-6, 7-dihydro-5 H-pyrazolo [5, 1-b][1, 3 …
C McBride, L Trzoss, D Povero, M Lazic, G Ambrus-Aikelin, A Santini, ...
Journal of Medicinal Chemistry 65 (21), 14721-14739, 2022
252022
Differential regulation of inflammation and apoptosis in Fas-resistant hepatocyte-specific Bid-deficient mice
M Lazic, A Eguchi, MP Berk, D Povero, B Papouchado, A Mulya, ...
Journal of hepatology 61 (1), 107-115, 2014
172014
JT002, a small molecule inhibitor of the NLRP3 inflammasome for the treatment of autoinflammatory disorders
G Ambrus-Aikelin, K Takeda, A Joetham, M Lazic, D Povero, AM Santini, ...
Scientific Reports 13 (1), 13524, 2023
52023
Pharmacology of a potent and novel inhibitor of the NOD-like receptor pyrin domain-containing protein 3 (NLRP3) inflammasome that attenuates development of nonalcoholic …
D Povero, M Lazic, C McBride, G Ambrus-Aikelin, R Stansfield, ...
Journal of Pharmacology and Experimental Therapeutics 386 (2), 242-258, 2023
32023
Hepatocytes release microparticles during lipotoxicity that have potent pro-angiogenic effects in vitro and in vivo through Vanin-1-dependent internalization: 116
D Povero, A Eguchi, M Lazic, C Johnson, M Parola, A Feldstein
Hepatology 56, 251A, 2012
22012
Discovery of Inhibitors of NLRP3 inflammasome assembly for the treatment of NASH and liver fibrosis
J Veal, C Mcbride, M Lazic, D Povero, G Ambrus, A Santini, R Stansfield, ...
Journal of Hepatology 68, S347-S348, 2018
12018
1271 REDUCED DIETARY OMEGA-6: OMEGA-3 RATIO AND 12/15-LIPOXYGENASE DEFICIENCY PROTECT FROM HIGH FAT DIET-INDUCED STEATOHEPATITIS
M Lazic, E Inzaugarat, D Povero, I Chen, M Chen, M Nalbandyan, ...
Journal of Hepatology, S514, 2013
12013
Hepatocyte-derived microparticles with a specific antigenic composition are released in blood during Nash development: implications for biomarkers development
D Povero, A Eguchi, C Johnson, A Wree, M Lazic, M Parola, AE Feldstein
Journal of Hepatology, S34-S34, 2013
12013
Author Correction: JT002, a small molecule inhibitor of the NLRP3 inflammasome for the treatment of autoinflammatory disorders
G Ambrus-Aikelin, K Takeda, A Joetham, M Lazic, D Povero, AM Santini, ...
Scientific Reports 13, 2023
2023
Perilipin a is a Novel Biomarker of Circulating Adipocyte-Derived Extracellular Vesicles in Both Murine Models of Obesity and Obese Humans
A Eguchi, M Lazic, AM Armando, SA Phillips, O Quehenberger, DD Sears, ...
Journal of Hepatology 2 (64), S672-S673, 2016
2016
Circulating extracellular vesicles with a specific Proteome and liver microRNAs are novel biomarkers for liver injury in fatty liver disease: 1095
D Povero, A Eguchi, H Li, C Johnson, A Wree, M Lazic, K Messer, ...
Hepatology 60, 733A, 2014
2014
P274 MICROPARTICLES FROM HYPERTROPHIED ADIPOCYTES OR OBESE MICE ACTIVATE MONOCYTES AND MACROPHAGES CONTRIBUTING TO LIVER INFLAMMATION
A Eguchi, M Lazic, A Mulya, MP Berk, A Gornicka, SA Phillips, DD Sears, ...
Journal of Hepatology 1 (60), S157, 2014
2014
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