Mycobacterium tuberculosis protein ESAT‐6 is a potent activator of the NLRP3/ASC inflammasome BB Mishra, P Moura‐Alves, A Sonawane, N Hacohen, G Griffiths, LF Moita, ... Cellular microbiology 12 (8), 1046-1063, 2010 | 403 | 2010 |
AhR sensing of bacterial pigments regulates antibacterial defence P Moura-Alves, K Faé, E Houthuys, A Dorhoi, A Kreuchwig, J Furkert, ... Nature 512 (7515), 387-392, 2014 | 376 | 2014 |
MicroRNA-223 controls susceptibility to tuberculosis by regulating lung neutrophil recruitment A Dorhoi, M Iannaccone, M Farinacci, KC Faé, J Schreiber, ... The Journal of clinical investigation 123 (11), 4836-4848, 2013 | 315 | 2013 |
Host monitoring of quorum sensing during Pseudomonas aeruginosa infection P Moura-Alves, A Puyskens, A Stinn, M Klemm, U Guhlich-Bornhof, ... Science 366 (6472), eaaw1629, 2019 | 121 | 2019 |
The Recombinant BCG ΔureC::hly Vaccine Targets the AIM2 Inflammasome to Induce Autophagy and Inflammation H Saiga, N Nieuwenhuizen, M Gengenbacher, AB Koehler, S Schuerer, ... The Journal of infectious diseases 211 (11), 1831-1841, 2015 | 91 | 2015 |
cGAS facilitates sensing of extracellular cyclic dinucleotides to activate innate immunity H Liu, P Moura‐Alves, G Pei, HJ Mollenkopf, R Hurwitz, X Wu, F Wang, ... EMBO reports 20 (4), e46293, 2019 | 63 | 2019 |
The E3 ubiquitin ligase NEDD4 enhances killing of membrane-perturbing intracellular bacteria by promoting autophagy G Pei, H Buijze, H Liu, P Moura-Alves, C Goosmann, V Brinkmann, ... Autophagy 13 (12), 2041-2055, 2017 | 61 | 2017 |
Cellular stress promotes NOD1/2‐dependent inflammation via the endogenous metabolite sphingosine‐1‐phosphate G Pei, J Zyla, L He, P Moura‐Alves, H Steinle, P Saikali, L Lozza, ... The EMBO journal 40 (13), e106272, 2021 | 47 | 2021 |
IL-36/LXR axis modulates cholesterol metabolism and immune defense to Mycobacterium tuberculosis F Ahsan, J Maertzdorf, U Guhlich-Bornhof, SHE Kaufmann, ... Scientific reports 8 (1), 1520, 2018 | 40 | 2018 |
Role of interleukin 36γ in host defense against tuberculosis F Ahsan, P Moura-Alves, U Guhlich-Bornhof, M Klemm, SHE Kaufmann, ... The Journal of infectious diseases 214 (3), 464-474, 2016 | 38 | 2016 |
Aryl hydrocarbon receptor modulation by tuberculosis drugs impairs host defense and treatment outcomes A Puyskens, A Stinn, M van der Vaart, A Kreuchwig, J Protze, G Pei, ... Cell host & microbe 27 (2), 238-248. e7, 2020 | 33 | 2020 |
Humanized Mouse Model Mimicking Pathology of Human Tuberculosis for in vivo Evaluation of Drug Regimens F Arrey, D Löwe, S Kuhlmann, P Kaiser, P Moura-Alves, ... Frontiers in immunology 10, 89, 2019 | 33 | 2019 |
Syndecans promote mycobacterial internalization by lung epithelial cells N Zimmermann, H Saiga, E Houthuys, P Moura‐Alves, A Koehler, ... Cellular microbiology 18 (12), 1846-1856, 2016 | 30 | 2016 |
COVID-19 is a multi-organ aggressor: epigenetic and clinical marks MM Kgatle, IO Lawal, G Mashabela, TMG Boshomane, PC Koatale, ... Frontiers in Immunology 12, 752380, 2021 | 29 | 2021 |
The Henna pigment Lawsone activates the Aryl Hydrocarbon Receptor and impacts skin homeostasis L Lozza, P Moura-Alves, T Domaszewska, C Lage Crespo, I Streata, ... Scientific reports 9 (1), 10878, 2019 | 25 | 2019 |
Targeting the aryl hydrocarbon receptor by gut phenolic metabolites: A strategy towards gut inflammation CJG Pinto, MÁ Ávila-Gálvez, Y Lian, P Moura-Alves, CN Dos Santos Redox Biology 61, 102622, 2023 | 19 | 2023 |
FX11 limits Mycobacterium tuberculosis growth and potentiates bactericidal activity of isoniazid through host-directed activity G Krishnamoorthy, P Kaiser, U Abu Abed, J Weiner III, P Moura-Alves, ... Disease models & mechanisms 13 (3), dmm041954, 2020 | 19 | 2020 |
An shRNA-based screen of splicing regulators identifies SFRS3 as a negative regulator of IL-1β secretion P Moura-Alves, A Neves-Costa, H Raquel, TR Pacheco, B D'Almeida, ... PLoS One 6 (5), e19829, 2011 | 17 | 2011 |
Sensing of mycobacterial arabinogalactan by galectin‐9 exacerbates mycobacterial infection X Wu, Y Wu, R Zheng, F Tang, L Qin, D Lai, L Zhang, L Chen, B Yan, ... EMBO reports 22 (7), e51678, 2021 | 13 | 2021 |
The insecticide chlorpyrifos modifies the expression of genes involved in the PXR and AhR pathways in the rainbow trout, Oncorhynchus mykiss JS De Anna, LA Darraz, JC Painefilú, JG Cárcamo, P Moura-Alves, ... Pesticide Biochemistry and Physiology 178, 104920, 2021 | 10 | 2021 |