Driver mutations in histone H3. 3 and chromatin remodelling genes in paediatric glioblastoma J Schwartzentruber, A Korshunov, XY Liu, DTW Jones, E Pfaff, K Jacob, ... Nature 482 (7384), 226-231, 2012 | 1815 | 2012 |
Hotspot mutations in H3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma D Sturm, H Witt, V Hovestadt, DA Khuong-Quang, DTW Jones, ... Cancer cell 22 (4), 425-437, 2012 | 1357 | 2012 |
A perfect message: RNA surveillance and nonsense-mediated decay MW Hentze, AE Kulozik Cell 96 (3), 307-310, 1999 | 944 | 1999 |
DNA methylation-based classification of central nervous system tumours D Capper, DTW Jones, M Sill, V Hovestadt, D Schrimpf, D Sturm, ... Nature 555 (7697), 469-474, 2018 | 750 | 2018 |
Dissecting the genomic complexity underlying medulloblastoma DTW Jones, N Jäger, M Kool, T Zichner, B Hutter, M Sultan, YJ Cho, ... Nature 488 (7409), 100-105, 2012 | 743 | 2012 |
Genome sequencing of pediatric medulloblastoma links catastrophic DNA rearrangements with TP53 mutations T Rausch, DTW Jones, M Zapatka, AM Stütz, T Zichner, J Weischenfeldt, ... Cell 148 (1-2), 59-71, 2012 | 687 | 2012 |
Nonsense-mediated decay approaches the clinic JA Holbrook, G Neu-Yilik, MW Hentze, AE Kulozik Nature genetics 36 (8), 801-808, 2004 | 635 | 2004 |
Molecular classification of ependymal tumors across all CNS compartments, histopathological grades, and age groups KW Pajtler, H Witt, M Sill, DTW Jones, V Hovestadt, F Kratochwil, K Wani, ... Cancer cell 27 (5), 728-743, 2015 | 595 | 2015 |
Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma DTW Jones, B Hutter, N Jäger, A Korshunov, M Kool, HJ Warnatz, ... Nature genetics 45 (8), 927-932, 2013 | 590 | 2013 |
A sensitive array for microRNA expression profiling (miChip) based on locked nucleic acids (LNA) M Castoldi, S Schmidt, V Benes, M Noerholm, AE Kulozik, MW Hentze, ... Rna 12 (5), 913-920, 2006 | 546 | 2006 |
Genome sequencing of SHH medulloblastoma predicts genotype-related response to smoothened inhibition M Kool, DTW Jones, N Jäger, PA Northcott, TJ Pugh, V Hovestadt, ... Cancer cell 25 (3), 393-405, 2014 | 527 | 2014 |
The landscape of genomic alterations across childhood cancers SN Gröbner, BC Worst, J Weischenfeldt, I Buchhalter, K Kleinheinz, ... Nature 555 (7696), 321-327, 2018 | 476 | 2018 |
Epigenomic alterations define lethal CIMP-positive ependymomas of infancy SC Mack, H Witt, RM Piro, L Gu, S Zuyderduyn, AM Stütz, X Wang, ... Nature 506 (7489), 445-450, 2014 | 469 | 2014 |
BRAF gene duplication constitutes a mechanism of MAPK pathway activation in low-grade astrocytomas S Pfister, WG Janzarik, M Remke, A Ernst, W Werft, N Becker, G Toedt, ... The Journal of clinical investigation 118 (5), 1739-1749, 2008 | 465 | 2008 |
Binary specification of nonsense codons by splicing and cytoplasmic translation R Thermann, G Neu‐Yilik, A Deters, U Frede, K Wehr, C Hagemeier, ... The EMBO journal 17 (12), 3484-3494, 1998 | 415 | 1998 |
Delineation of two clinically and molecularly distinct subgroups of posterior fossa ependymoma H Witt, SC Mack, M Ryzhova, S Bender, M Sill, R Isserlin, A Benner, ... Cancer cell 20 (2), 143-157, 2011 | 402 | 2011 |
Enhancer hijacking activates GFI1 family oncogenes in medulloblastoma PA Northcott, C Lee, T Zichner, AM Stütz, S Erkek, D Kawauchi, DJH Shih, ... Nature 511 (7510), 428-434, 2014 | 398 | 2014 |
Outcome Prediction in Pediatric Medulloblastoma Based on DNA Copy-Number Aberrations of Chromosomes 6q and 17q and the MYC and MYCN Loci S Pfister, M Remke, A Benner, F Mendrzyk, G Toedt, J Felsberg, ... Journal of clinical oncology 27 (10), 1627-1636, 2009 | 323 | 2009 |
Gain-of-function mutations in interleukin-7 receptor-α (IL7R) in childhood acute lymphoblastic leukemias C Shochat, N Tal, OR Bandapalli, C Palmi, I Ganmore, G te Kronnie, ... The Journal of experimental medicine 208 (5), 901-908, 2011 | 316 | 2011 |
Interactions between UPF1, eRFs, PABP and the exon junction complex suggest an integrated model for mammalian NMD pathways PV Ivanov, NH Gehring, JB Kunz, MW Hentze, AE Kulozik The EMBO journal 27 (5), 736-747, 2008 | 307 | 2008 |