Xiaoguang Fang
Xiaoguang Fang
Trailhead Biosystems
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Glioblastoma stem cells generate vascular pericytes to support vessel function and tumor growth
L Cheng, Z Huang, W Zhou, Q Wu, S Donnola, JK Liu, X Fang, AE Sloan, ...
Cell 153 (1), 139-152, 2013
Periostin secreted by glioblastoma stem cells recruits M2 tumour-associated macrophages and promotes malignant growth
W Zhou, SQ Ke, Z Huang, W Flavahan, X Fang, J Paul, L Wu, AE Sloan, ...
Nature cell biology 17 (2), 170-182, 2015
MicroRNAs: novel regulators in the hallmarks of human cancer
K Ruan, X Fang, G Ouyang
Cancer letters 285 (2), 116-126, 2009
Mitochondrial control by DRP1 in brain tumor initiating cells
Q Xie, Q Wu, CM Horbinski, WA Flavahan, K Yang, W Zhou, ...
Nature neuroscience 18 (4), 501-510, 2015
Twist2 contributes to breast cancer progression by promoting an epithelial–mesenchymal transition and cancer stem-like cell self-renewal
X Fang, Y Cai, J Liu, Z Wang, Q Wu, Z Zhang, CJ Yang, L Yuan, ...
Oncogene 30 (47), 4707-4720, 2011
N6-methyladenine DNA modification in glioblastoma
Q Xie, TP Wu, RC Gimple, Z Li, BC Prager, Q Wu, Y Yu, P Wang, Y Wang, ...
Cell 175 (5), 1228-1243. e20, 2018
Tumour-associated macrophages secrete pleiotrophin to promote PTPRZ1 signalling in glioblastoma stem cells for tumour growth
Y Shi, YF Ping, W Zhou, ZC He, C Chen, BSJ Bian, L Zhang, L Chen, ...
Nature communications 8 (1), 1-17, 2017
Molecular signaling of the epithelial to mesenchymal transition in generating and maintaining cancer stem cells
G Ouyang, Z Wang, X Fang, J Liu, CJ Yang
Cellular and Molecular Life Sciences 67 (15), 2605-2618, 2010
Reciprocal signaling between glioblastoma stem cells and differentiated tumor cells promotes malignant progression
X Wang, BC Prager, Q Wu, LJY Kim, RC Gimple, Y Shi, K Yang, ...
Cell stem cell 22 (4), 514-528. e5, 2018
Targeting glioma stem cell-derived pericytes disrupts the blood-tumor barrier and improves chemotherapeutic efficacy
W Zhou, C Chen, Y Shi, Q Wu, RC Gimple, X Fang, Z Huang, K Zhai, ...
Cell stem cell 21 (5), 591-603. e4, 2017
Purine synthesis promotes maintenance of brain tumor initiating cells in glioma
X Wang, K Yang, Q Xie, Q Wu, SC Mack, Y Shi, LJY Kim, BC Prager, ...
Nature neuroscience 20 (5), 661-673, 2017
Sema3C promotes the survival and tumorigenicity of glioma stem cells through Rac1 activation
J Man, J Shoemake, W Zhou, X Fang, Q Wu, A Rizzo, R Prayson, S Bao, ...
Cell reports 9 (5), 1812-1826, 2014
Deubiquitinase USP13 maintains glioblastoma stem cells by antagonizing FBXL14-mediated Myc ubiquitination
X Fang, W Zhou, Q Wu, Z Huang, Y Shi, K Yang, C Chen, Q Xie, SC Mack, ...
Journal of Experimental Medicine 214 (1), 245-267, 2017
MYC-regulated mevalonate metabolism maintains brain tumor–initiating cells
X Wang, Z Huang, Q Wu, BC Prager, SC Mack, K Yang, LJY Kim, ...
Cancer research 77 (18), 4947-4960, 2017
Ibrutinib inactivates BMX-STAT3 in glioma stem cells to impair malignant growth and radioresistance
Y Shi, OA Guryanova, W Zhou, C Liu, Z Huang, X Fang, X Wang, C Chen, ...
Science translational medicine 10 (443), eaah6816, 2018
Periostin contributes to the acquisition of multipotent stem cell-like properties in human mammary epithelial cells and breast cancer cells
X Wang, J Liu, Z Wang, Y Huang, W Liu, X Zhu, Y Cai, X Fang, S Lin, ...
PloS one 8 (8), e72962, 2013
Twist2 promotes self-renewal of liver cancer stem-like cells by regulating CD24
AY Liu, Y Cai, Y Mao, Y Lin, H Zheng, T Wu, Y Huang, X Fang, S Lin, ...
Carcinogenesis 35 (3), 537-545, 2014
Tetraspanin CD9 stabilizes gp130 by preventing its ubiquitin-dependent lysosomal degradation to promote STAT3 activation in glioma stem cells
Y Shi, W Zhou, L Cheng, C Chen, Z Huang, X Fang, Q Wu, Z He, S Xu, ...
Cell Death & Differentiation 24 (1), 167-180, 2017
Cancer stem cells: a potential target for cancer therapy
H Qiu, X Fang, Q Luo, G Ouyang
Cellular and molecular life sciences 72 (18), 3411-3424, 2015
The zinc finger transcription factor ZFX is required for maintaining the tumorigenic potential of glioblastoma stem cells
X Fang, Z Huang, W Zhou, Q Wu, AE Sloan, G Ouyang, RE McLendon, ...
Stem cells 32 (8), 2033-2047, 2014
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