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Nikolai Siemens
Nikolai Siemens
University of Greifswald
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Zitiert von
Jahr
Biofilm in group A streptococcal necrotizing soft tissue infections
N Siemens, B Chakrakodi, SM Shambat, M Morgan, H Bergsten, ...
JCI insight 1 (10), 2016
742016
Streptococcus pyogenes M49 plasminogen/plasmin binding facilitates keratinocyte invasion via integrin-integrin-linked kinase (ILK) pathways and protects from macrophage killing
N Siemens, N Patenge, J Otto, T Fiedler, B Kreikemeyer
Journal of Biological Chemistry 286 (24), 21612-21622, 2011
722011
Modelling staphylococcal pneumonia in a human 3D lung tissue model system delineates toxin-mediated pathology
S Mairpady Shambat, P Chen, AT Nguyen Hoang, H Bergsten, ...
Disease models & mechanisms 8 (11), 1413-1425, 2015
582015
Differential neutrophil responses to bacterial stimuli: Streptococcal strains are potent inducers of heparin-binding protein and resistin-release
J Snäll, A Linnér, J Uhlmann, N Siemens, H Ibold, M Janos, A Linder, ...
Scientific reports 6 (1), 21288, 2016
532016
Port d’Entrée for respiratory infections–Does the influenza a virus pave the way for bacteria?
N Siemens, S Oehmcke-Hecht, TC Mettenleiter, B Kreikemeyer, ...
Frontiers in microbiology 8, 2602, 2017
392017
The role of streptococcal and staphylococcal exotoxins and proteases in human necrotizing soft tissue infections
P Shumba, S Mairpady Shambat, N Siemens
Toxins 11 (6), 332, 2019
352019
A point mutation in AgrC determines cytotoxic or colonizing properties associated with phenotypic variants of ST22 MRSA strains
S Mairpady Shambat, N Siemens, IR Monk, DB Mohan, S Mukundan, ...
Scientific reports 6 (1), 31360, 2016
342016
Genetic architecture of group A streptococcal necrotizing soft tissue infections in the mouse
K Chella Krishnan, S Mukundan, J Alagarsamy, J Hur, S Nookala, ...
PLoS pathogens 12 (7), e1005732, 2016
342016
Increased cytotoxicity and streptolysin O activity in group G streptococcal strains causing invasive tissue infections
N Siemens, BR Kittang, B Chakrakodi, O Oppegaard, L Johansson, ...
Scientific Reports 5 (1), 16945, 2015
332015
LL-37 triggers formation of Streptococcus pyogenes extracellular vesicle-like structures with immune stimulatory properties
J Uhlmann, M Rohde, N Siemens, B Kreikemeyer, P Bergman, ...
Journal of innate immunity 8 (3), 243-257, 2016
322016
Characterization of Three Lactic Acid Bacteria and Their Isogenic ldh Deletion Mutants Shows Optimization for Y ATP (Cell Mass Produced per Mole of ATP) at …
T Fiedler, M Bekker, M Jonsson, I Mehmeti, A Pritzschke, N Siemens, ...
Applied and environmental microbiology 77 (2), 612-617, 2011
322011
The extracellular protein factor Epf from Streptococcus pyogenes is a cell surface adhesin that binds to cells through an N-terminal domain containing a carbohydrate-binding module
C Linke, N Siemens, S Oehmcke, M Radjainia, RHP Law, JC Whisstock, ...
Journal of Biological Chemistry 287 (45), 38178-38189, 2012
312012
Effects of the ERES pathogenicity region regulator Ralp3 on Streptococcus pyogenes serotype M49 virulence factor expression
N Siemens, T Fiedler, J Normann, J Klein, R Münch, N Patenge, ...
Journal of bacteriology 194 (14), 3618-3626, 2012
312012
Hydrogen peroxide is crucial for NLRP3 inflammasome-mediated IL-1β production and cell death in pneumococcal infections of bronchial epithelial cells
S Surabhi, LH Jachmann, P Shumba, G Burchhardt, S Hammerschmidt, ...
Journal of Innate Immunity 14 (3), 192-206, 2022
292022
The role of NLRP3 inflammasome in pneumococcal infections
S Surabhi, F Cuypers, S Hammerschmidt, N Siemens
Frontiers in Immunology 11, 614801, 2020
232020
Prothrombotic and proinflammatory activities of the β-hemolytic group B streptococcal pigment
N Siemens, S Oehmcke-Hecht, J Hoßmann, SB Skorka, RHT Nijhuis, ...
Journal of innate immunity 12 (4), 291-303, 2020
172020
Phosphoglycerate kinase—a novel streptococcal factor involved in neutrophil activation and degranulation
J Uhlmann, N Siemens, Y Kai-Larsen, T Fiedler, P Bergman, L Johansson, ...
The Journal of Infectious Diseases 214 (12), 1876-1883, 2016
162016
Innate immune responses at the asymptomatic stage of influenza A viral infections of Streptococcus pneumoniae colonized and non-colonized mice
F Cuypers, A Schäfer, SB Skorka, S Surabhi, LA Tölken, AD Paulikat, ...
Scientific reports 11 (1), 20609, 2021
142021
Glycoconjugated Phthalocyanines as Photosensitizers for PDT–Overcoming Aggregation in Solution
F Bächle, N Siemens, T Ziegler
European Journal of Organic Chemistry 2019 (42), 7089-7116, 2019
142019
Adenosine triphosphate neutralizes pneumolysin-induced neutrophil activation
F Cuypers, B Klabunde, M Gesell Salazar, S Surabhi, SB Skorka, ...
The Journal of Infectious Diseases 222 (10), 1702-1712, 2020
122020
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