| Small molecule inhibition of the KRAS–PDEδ interaction impairs oncogenic KRAS signalling G Zimmermann, B Papke, S Ismail, N Vartak, A Chandra, M Hoffmann, ... Nature 497 (7451), 638-642, 2013 | 707 | 2013 |
| The palmitoylation machinery is a spatially organizing system for peripheral membrane proteins O Rocks, M Gerauer, N Vartak, S Koch, ZP Huang, M Pechlivanis, ... Cell 141 (3), 458-471, 2010 | 496 | 2010 |
| Small-molecule inhibition of APT1 affects Ras localization and signaling FJ Dekker, O Rocks, N Vartak, S Menninger, C Hedberg, R Balamurugan, ... Nature chemical biology 6 (6), 449-456, 2010 | 423 | 2010 |
| The ascending pathophysiology of cholestatic liver disease PLM Jansen, A Ghallab, N Vartak, R Reif, FG Schaap, J Hampe, ... Hepatology 65 (2), 722-738, 2017 | 322 | 2017 |
| KRas localizes to the plasma membrane by spatial cycles of solubilization, trapping and vesicular transport M Schmick, N Vartak, B Papke, M Kovacevic, DC Truxius, L Rossmannek, ... Cell 157 (2), 459-471, 2014 | 266 | 2014 |
| Cholestasis-induced adaptive remodeling of interlobular bile ducts N Vartak, A Damle-Vartak, B Richter, O Dirsch, U Dahmen, S Hammad, ... Hepatology 63 (3), 951–964, 2016 | 146 | 2016 |
| Prediction of human drug-induced liver injury (DILI) in relation to oral doses and blood concentrations W Albrecht, F Kappenberg, T Brecklinghaus, R Stoeber, R Marchan, ... Archives of toxicology 93, 1609-1637, 2019 | 108 | 2019 |
| Bile microinfarcts in cholestasis are initiated by rupture of the apical hepatocyte membrane and cause shunting of bile to sinusoidal blood A Ghallab, U Hofmann, S Sezgin, N Vartak, R Hassan, A Zaza, P Godoy, ... Hepatology 69 (2), 666-683, 2019 | 104 | 2019 |
| The autodepalmitoylating activity of APT maintains the spatial organization of palmitoylated membrane proteins N Vartak, B Papke, HE Grecco, L Rossmannek, H Waldmann, C Hedberg, ... Biophysical journal 106 (1), 93-105, 2014 | 98 | 2014 |
| Development of highly potent inhibitors of the Ras‐targeting human acyl protein thioesterases based on substrate similarity design C Hedberg, FJ Dekker, M Rusch, S Renner, S Wetzel, N Vartak, ... Angewandte Chemie 123 (42), 10006-10011, 2011 | 85 | 2011 |
| miRs-138 and-424 control palmitoylation-dependent CD95-mediated cell death by targeting acyl protein thioesterases 1 and 2 in CLL V Berg, M Rusch, N Vartak, C Jüngst, A Schauss, H Waldmann, ... Blood, The Journal of the American Society of Hematology 125 (19), 2948-2957, 2015 | 63 | 2015 |
| Single cell polarity in liquid phase facilitates tumour metastasis A Lorentzen, PF Becker, J Kosla, M Saini, K Weidele, P Ronchi, C Klein, ... Nature communications 9 (1), 887, 2018 | 56 | 2018 |
| Regulation of Ras localization by acylation enables a mode of intracellular signal propagation A Lorentzen, A Kinkhabwala, O Rocks, N Vartak, PIH Bastiaens Science signaling 3 (140), ra68-ra68, 2010 | 54 | 2010 |
| Activated ErbB3 translocates to the nucleus via clathrin-independent endocytosis, which is associated with proliferating cells R Reif, A Adawy, N Vartak, J Schröder, G Günther, A Ghallab, M Schmidt, ... Journal of Biological Chemistry 291 (8), 3837-3847, 2016 | 42 | 2016 |
| Spatial cycles in G‐protein crowd control N Vartak, P Bastiaens The EMBO journal 29 (16), 2689-2699, 2010 | 42 | 2010 |
| Intravital dynamic and correlative imaging of mouse livers reveals diffusion‐dominated canalicular and flow‐augmented ductular bile flux N Vartak, G Guenther, F Joly, A Damle‐Vartak, G Wibbelt, J Fickel, S Jörs, ... Hepatology 73 (4), 1531-1550, 2021 | 40 | 2021 |
| Inhibition of the renal apical sodium dependent bile acid transporter prevents cholemic nephropathy in mice with obstructive cholestasis A Ghallab, D González, E Strängberg, U Hofmann, M Myllys, R Hassan, ... Journal of hepatology 80 (2), 268-281, 2024 | 26 | 2024 |
| Chemical‐Biological Exploration of the Limits of the Ras De‐and Repalmitoylating Machinery K Görmer, M Bürger, JAW Kruijtzer, I Vetter, N Vartak, L Brunsveld, ... ChemBioChem 13 (7), 1017-1023, 2012 | 23 | 2012 |
| The hepatocyte export carrier inhibition assay improves the separation of hepatotoxic from non-hepatotoxic compounds T Brecklinghaus, W Albrecht, F Kappenberg, J Duda, N Vartak, K Edlund, ... Chemico-biological interactions 351, 109728, 2022 | 20 | 2022 |
| Basic concepts of mixture toxicity and relevance for risk evaluation and regulation D Bloch, P Diel, B Epe, M Hellwig, A Lampen, A Mally, D Marko, ... Archives of toxicology 97 (11), 3005-3017, 2023 | 15 | 2023 |
Eli ZamirDivision of Microbiome and Cancer, German Cancer Research Center (DKFZ)Bestätigte E-Mail-Adresse bei dkfz-heidelberg.de
