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Marc Hild
Marc Hild
Senior Investigator I, Novartis Institutes for BioMedical Research
Bestätigte E-Mail-Adresse bei novartis.com
Titel
Zitiert von
Zitiert von
Jahr
Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling
SMA Huang, YM Mishina, S Liu, A Cheung, F Stegmeier, GA Michaud, ...
Nature 461 (7264), 614-620, 2009
21712009
Bidirectional transport of amino acids regulates mTOR and autophagy
P Nicklin, P Bergman, B Zhang, E Triantafellow, H Wang, B Nyfeler, ...
Cell 136 (3), 521-534, 2009
19432009
HDAC6 rescues neurodegeneration and provides an essential link between autophagy and the UPS
UB Pandey, Z Nie, Y Batlevi, BA McCray, GP Ritson, NB Nedelsky, ...
Nature 447 (7146), 860-864, 2007
14272007
Structure of the DDB1–CRBN E3 ubiquitin ligase in complex with thalidomide
ES Fischer, K Böhm, JR Lydeard, H Yang, MB Stadler, S Cavadini, ...
Nature 512 (7512), 49-53, 2014
9352014
Genome-Wide RNAi Analysis of Growth and Viability in Drosophila Cells
M Boutros, AA Kiger, S Armknecht, K Kerr, M Hild, B Koch, SA Haas, ...
Science 303 (5659), 832-835, 2004
8922004
RNF146 is a poly (ADP-ribose)-directed E3 ligase that regulates axin degradation and Wnt signalling
Y Zhang, S Liu, C Mickanin, Y Feng, O Charlat, GA Michaud, M Schirle, ...
Nature cell biology 13 (5), 623-629, 2011
4232011
SMN2 splice modulators enhance U1–pre-mRNA association and rescue SMA mice
J Palacino, SE Swalley, C Song, AK Cheung, L Shu, X Zhang, ...
Nature chemical biology 11 (7), 511-517, 2015
4132015
SMN2 splice modulators enhance U1–pre-mRNA association and rescue SMA mice
J Palacino, SE Swalley, C Song, AK Cheung, L Shu, X Zhang, ...
Nature chemical biology 11 (7), 511-517, 2015
4132015
SMN2 splice modulators enhance U1–pre-mRNA association and rescue SMA mice
J Palacino, SE Swalley, C Song, AK Cheung, L Shu, X Zhang, ...
Nature chemical biology 11 (7), 511-517, 2015
4132015
SMN2 splice modulators enhance U1–pre-mRNA association and rescue SMA mice
J Palacino, SE Swalley, C Song, AK Cheung, L Shu, X Zhang, ...
Nature chemical biology 11 (7), 511-517, 2015
4132015
Zebrafish ΔNp63 is a direct target of Bmp signaling and encodes a transcriptional repressor blocking neural specification in the ventral ectoderm
J Bakkers, M Hild, C Kramer, M Furutani-Seiki, M Hammerschmidt
Developmental cell 2 (5), 617-627, 2002
2742002
Essential role of Bmp7 (snailhouse) and its prodomain in dorsoventral patterning of the zebrafish embryo
A Dick, M Hild, H Bauer, Y Imai, H Maifeld, AF Schier, WS Talbot, ...
Development 127 (2), 343-354, 2000
2632000
Notch2 is required for inflammatory cytokine-driven goblet cell metaplasia in the lung
H Danahay, AD Pessotti, J Coote, BE Montgomery, D Xia, A Wilson, ...
Cell reports 10 (2), 239-252, 2015
2312015
The smad5 mutation somitabun blocks Bmp2b signaling during early dorsoventral patterning of the zebrafish embryo
M Hild, A Dick, GJ Rauch, A Meier, T Bouwmeester, P Haffter, ...
Development 126 (10), 2149-2159, 1999
2251999
R-Spondin potentiates Wnt/β-catenin signaling through orphan receptors LGR4 and LGR5
H Ruffner, J Sprunger, O Charlat, J Leighton-Davies, B Grosshans, ...
PloS one 7 (7), e40976, 2012
2072012
Localized H3K36 methylation states define histone H4K16 acetylation during transcriptional elongation in Drosophila
O Bell, C Wirbelauer, M Hild, AND Scharf, M Schwaiger, DM MacAlpine, ...
The EMBO journal 26 (24), 4974-4984, 2007
1742007
DRUG-seq for miniaturized high-throughput transcriptome profiling in drug discovery
C Ye, DJ Ho, M Neri, C Yang, T Kulkarni, R Randhawa, M Henault, ...
Nature communications 9 (1), 4307, 2018
1622018
An integrated gene annotation and transcriptional profiling approach towards the full gene content of the Drosophila genome
M Hild, B Beckmann, SA Haas, B Koch, V Solovyev, C Busold, ...
Genome biology 5, 1-17, 2003
1362003
Follistatin and noggin are excluded from the zebrafish organizer
H Bauer, A Meier, M Hild, S Stachel, A Economides, D Hazelett, ...
Developmental biology 204 (2), 488-507, 1998
1331998
Discovery of small molecule splicing modulators of survival motor neuron-2 (SMN2) for the treatment of spinal muscular atrophy (SMA)
AK Cheung, B Hurley, R Kerrigan, L Shu, DN Chin, Y Shen, G O’Brien, ...
Journal of medicinal chemistry 61 (24), 11021-11036, 2018
1222018
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