Coupling of Gab1 to c-Met, Grb2, and Shp2 mediates biological responses U Schaeper, NH Gehring, KP Fuchs, M Sachs, B Kempkes, W Birchmeier The Journal of cell biology 149 (7), 1419-1432, 2000 | 492 | 2000 |
Interactions between UPF1, eRFs, PABP and the exon junction complex suggest an integrated model for mammalian NMD pathways PV Ivanov, NH Gehring, JB Kunz, MW Hentze, AE Kulozik The EMBO journal 27 (5), 736-747, 2008 | 394 | 2008 |
Exon-junction complex components specify distinct routes of nonsense-mediated mRNA decay with differential cofactor requirements NH Gehring, JB Kunz, G Neu-Yilik, S Breit, MH Viegas, MW Hentze, ... Molecular cell 20 (1), 65-75, 2005 | 369 | 2005 |
Y14 and hUpf3b form an NMD-activating complex NH Gehring, G Neu-Yilik, T Schell, MW Hentze, AE Kulozik Molecular cell 11 (4), 939-949, 2003 | 364 | 2003 |
Increased efficiency of mRNA 3′ end formation: a new genetic mechanism contributing to hereditary thrombophilia NH Gehring, U Frede, G Neu-Yilik, P Hundsdoerfer, B Vetter, MW Hentze, ... Nature genetics 28 (4), 389-392, 2001 | 358 | 2001 |
Disassembly of exon junction complexes by PYM NH Gehring, S Lamprinaki, AE Kulozik, MW Hentze Cell 137 (3), 536-548, 2009 | 214 | 2009 |
Mechanism of escape from nonsense-mediated mRNA decay of human β-globin transcripts with nonsense mutations in the first exon G Neu-Yilik, B Amthor, NH Gehring, S Bahri, H Paidassi, MW Hentze, ... Rna 17 (5), 843-854, 2011 | 168 | 2011 |
Functions of hUpf3a and hUpf3b in nonsense-mediated mRNA decay and translation JB Kunz, G Neu-Yilik, MW Hentze, AE Kulozik, NH Gehring Rna 12 (6), 1015-1022, 2006 | 164 | 2006 |
Unusual bipartite mode of interaction between the nonsense‐mediated decay factors, UPF1 and UPF2 M Clerici, A Mourão, I Gutsche, NH Gehring, MW Hentze, A Kulozik, ... The EMBO journal 28 (15), 2293-2306, 2009 | 159 | 2009 |
The hierarchy of exon-junction complex assembly by the spliceosome explains key features of mammalian nonsense-mediated mRNA decay NH Gehring, S Lamprinaki, MW Hentze, AE Kulozik PLoS biology 7 (5), e1000120, 2009 | 157 | 2009 |
Exon junction complexes: supervising the gene expression assembly line V Boehm, NH Gehring Trends in Genetics 32 (11), 724-735, 2016 | 144 | 2016 |
The C-terminal SH3 domain of the adapter protein Grb2 binds with high affinity to sequences in Gab1 and SLP-76 which lack the SH3-typical PxxP core motif M Lewitzky, C Kardinal, NH Gehring, EK Schmidt, B Konkol, M Eulitz, ... Oncogene 20 (9), 1052-1062, 2001 | 144 | 2001 |
Using the λN peptide to tether proteins to RNAs J Baron-Benhamou, NH Gehring, AE Kulozik, MW Hentze MRNA Processing and Metabolism: Methods and Protocols, 135-153, 2004 | 142 | 2004 |
Deciphering the mRNP code: RNA-bound determinants of post-transcriptional gene regulation NH Gehring, E Wahle, U Fischer Trends in biochemical sciences 42 (5), 369-382, 2017 | 136 | 2017 |
Anything but ordinary–emerging splicing mechanisms in eukaryotic gene regulation NH Gehring, JY Roignant Trends in Genetics 37 (4), 355-372, 2021 | 134 | 2021 |
IGHMBP2 is a ribosome-associated helicase inactive in the neuromuscular disorder distal SMA type 1 (DSMA1) UP Guenther, L Handoko, B Laggerbauer, S Jablonka, A Chari, ... Human molecular genetics 18 (7), 1288-1300, 2009 | 132 | 2009 |
The abundance of RNPS1, a protein component of the exon junction complex, can determine the variability in efficiency of the Nonsense Mediated Decay pathway MH Viegas, NH Gehring, S Breit, MW Hentze, AE Kulozik Nucleic acids research 35 (13), 4542-4551, 2007 | 131 | 2007 |
CWC22 connects pre-mRNA splicing and exon junction complex assembly AL Steckelberg, V Boehm, AM Gromadzka, NH Gehring Cell reports 2 (3), 454-461, 2012 | 126 | 2012 |
Unexpected roles for UPF1 in HIV-1 RNA metabolism and translation L Ajamian, L Abrahamyan, M Milev, PV Ivanov, AE Kulozik, NH Gehring, ... Rna 14 (5), 914-927, 2008 | 122 | 2008 |
The human intronless melanocortin 4-receptor gene is NMD insensitive KS Brocke, G Neu-Yilik, NH Gehring, MW Hentze, AE Kulozik Human molecular genetics 11 (3), 331-335, 2002 | 113 | 2002 |