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Robert J. Lefkowitz
Robert J. Lefkowitz
James B. Duke Professor of Medicine, Biochemistry, Chemistry; HHMI, Duke University
Verified email at receptor-biol.duke.edu - Homepage
Title
Cited by
Cited by
Year
Seven-transmembrane receptors
KL Pierce, RT Premont, RJ Lefkowitz
Nature reviews Molecular cell biology 3 (9), 639-650, 2002
35922002
Transduction of receptor signals by ß-arrestins
RJ Lefkowitz, SK Shenoy
science 308 (5721), 512-517, 2005
21282005
A ternary complex model explains the agonist-specific binding properties of the adenylate cyclase-coupled beta-adrenergic receptor.
A De Lean, JM Stadel, RJ Lefkowitz
Journal of Biological Chemistry 255 (15), 7108-7117, 1980
20871980
β-Arrestin-dependent formation of β2 adrenergic receptor-Src protein kinase complexes
LM Luttrell, S Ferguson, Y Daaka, WE Miller, S Maudsley, GJ Della Rocca, ...
Science 283 (5402), 655-661, 1999
18741999
Model systems for the study of seven-transmembrane-segment receptors
HG Dohlman, J Thorner, MG Caron, RJ Lefkowitz
Annual review of biochemistry 60 (1), 653-688, 1991
18731991
Cloning of the gene and cDNA for mammalian β-adrenergic receptor and homology with rhodopsin
RAF Dixon, BK Kobilka, DJ Strader, JL Benovic, HG Dohlman, T Frielle, ...
Nature 321 (6065), 75-79, 1986
17361986
β-arrestins and cell signaling
SM DeWire, S Ahn, RJ Lefkowitz, SK Shenoy
Annu. Rev. Physiol. 69, 483-510, 2007
17062007
Turning off the signal: desensitization of β‐adrenergic receptor function
WP Hausdorff, MG Caron, RJ Lefkowitz
The FASEB Journal 4 (11), 2881-2889, 1990
16981990
Switching of the coupling of the β2-adrenergic receptor to different G proteins by protein kinase A
Y Daaka, LM Luttrell, RJ Lefkowitz
Nature 390 (6655), 88-91, 1997
16571997
Intemational union of pharmacology nomenclature of adrenoceptors
B Db
Pharmacol Rev 46, 121-136, 1994
16501994
G protein–coupled receptor kinases
JA Pitcher, NJ Freedman, RJ Lefkowitz
Annual review of biochemistry 67 (1), 653-692, 1998
16341998
A mutation-induced activated state of the beta 2-adrenergic receptor. Extending the ternary complex model.
P Samama, S Cotecchia, T Costa, RJ Lefkowitz
Journal of Biological Chemistry 268 (7), 4625-4636, 1993
15781993
β-Arrestin: a protein that regulates β-adrenergic receptor function
MJ Lohse, JL Benovic, J Codina, MG Caron, RJ Lefkowitz
Science 248 (4962), 1547-1550, 1990
15521990
The role of β-arrestins in the termination and transduction of G-protein-coupled receptor signals
LM Luttrell, RJ Lefkowitz
Journal of cell science 115 (3), 455-465, 2002
15142002
G protein-coupled receptors: III. New roles for receptor kinases and β-arrestins in receptor signaling and desensitization
RJ Lefkowitz
Journal of Biological Chemistry 273 (30), 18677-18680, 1998
14261998
Seven-transmembrane-spanning receptors and heart function
HA Rockman, WJ Koch, RJ Lefkowitz
Nature 415 (6868), 206-212, 2002
12952002
Enhanced morphine analgesia in mice lacking β-arrestin 2
LM Bohn, RJ Lefkowitz, RR Gainetdinov, K Peppel, MG Caron, FT Lin
Science 286 (5449), 2495-2498, 1999
12221999
An Akt/β-arrestin 2/PP2A signaling complex mediates dopaminergic neurotransmission and behavior
JM Beaulieu, TD Sotnikova, S Marion, RJ Lefkowitz, RR Gainetdinov, ...
Cell 122 (2), 261-273, 2005
11642005
μ-Opioid receptor desensitization by β-arrestin-2 determines morphine tolerance but not dependence
LM Bohn, RR Gainetdinov, FT Lin, RJ Lefkowitz, MG Caron
Nature 408 (6813), 720-723, 2000
11062000
β-Arrestin 2: a receptor-regulated MAPK scaffold for the activation of JNK3
PH McDonald, CW Chow, WE Miller, SA Laporte, ME Field, FT Lin, ...
Science 290 (5496), 1574-1577, 2000
10462000
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