|Cbl-b regulates the CD28 dependence of T-cell activation|
YJ Chiang, HK Kole, K Brown, M Naramura, S Fukuhara, RJ Hu, IK Jang, ...
Nature 403 (6766), 216-220, 2000
|A novel PDZ domain containing guanine nucleotide exchange factor links heterotrimeric G proteins to Rho|
S Fukuhara, C Murga, M Zohar, T Igishi, JS Gutkind
Journal of Biological Chemistry 274 (9), 5868-5879, 1999
|Cyclic AMP potentiates vascular endothelial cadherin-mediated cell-cell contact to enhance endothelial barrier function through an Epac-Rap1 signaling pathway|
S Fukuhara, A Sakurai, H Sano, A Yamagishi, S Somekawa, N Takakura, ...
Molecular and cellular biology 25 (1), 136-146, 2005
|Differential function of Tie2 at cell–cell contacts and cell–substratum contacts regulated by angiopoietin-1|
S Fukuhara, K Sako, T Minami, K Noda, HZ Kim, T Kodama, M Shibuya, ...
Nature cell biology 10 (5), 513-526, 2008
|Angiopoietin-like protein 2 promotes chronic adipose tissue inflammation and obesity-related systemic insulin resistance|
M Tabata, T Kadomatsu, S Fukuhara, K Miyata, Y Ito, M Endo, T Urano, ...
Cell metabolism 10 (3), 178-188, 2009
|Identification of multiple novel epididymis-specific β-defensin isoforms in humans and mice|
Y Yamaguchi, T Nagase, R Makita, S Fukuhara, T Tomita, T Tominaga, ...
The Journal of Immunology 169 (5), 2516-2523, 2002
|Leukemia‐associated Rho guanine nucleotide exchange factor (LARG) links heterotrimeric G proteins of the G12 family to Rho|
S Fukuhara, H Chikumi, JS Gutkind
FEBS letters 485 (2-3), 183-188, 2000
|The sphingosine-1-phosphate transporter Spns2 expressed on endothelial cells regulates lymphocyte trafficking in mice|
S Fukuhara, S Simmons, S Kawamura, A Inoue, Y Orba, T Tokudome, ...
The Journal of clinical investigation 122 (4), 1416-1426, 2012
|RGS-containing RhoGEFs: the missing link between transforming G proteins and Rho?|
S Fukuhara, H Chikumi, JS Gutkind
Oncogene 20 (13), 1661-1668, 2001
|The E1784K mutation in SCN5A is associated with mixed clinical phenotype of type 3 long QT syndrome|
N Makita, E Behr, W Shimizu, M Horie, A Sunami, L Crotti, E Schulze-Bahr, ...
The Journal of clinical investigation 118 (6), 2219-2229, 2008
|A novel role for phosphatidylinositol 3-kinase β in signaling from G protein-coupled receptors to Akt|
C Murga, S Fukuhara, JS Gutkind
Journal of Biological Chemistry 275 (16), 12069-12073, 2000
|Angiopoietin-1Tie2 receptor signaling in vascular quiescence and angiogenesis|
S Fukuhara, K Sako, K Noda, J Zhang, M Minami, N Mochizuki
Histology and histopathology, 2010
|Regulation of G protein-linked guanine nucleotide exchange factors for Rho, PDZ-RhoGEF, and LARG by tyrosine phosphorylation: evidence of a role for focal adhesion kinase|
H Chikumi, S Fukuhara, JS Gutkind
Journal of Biological Chemistry 277 (14), 12463-12473, 2002
|Conformational switch of angiotensin II type 1 receptor underlying mechanical stress‐induced activation|
N Yasuda, S Miura, H Akazawa, T Tanaka, Y Qin, Y Kiya, S Imaizumi, ...
EMBO reports 9 (2), 179-186, 2008
|Flow-dependent endothelial YAP regulation contributes to vessel maintenance|
H Nakajima, K Yamamoto, S Agarwala, K Terai, H Fukui, S Fukuhara, ...
Developmental cell 40 (6), 523-536. e6, 2017
|Tip cell-specific requirement for an atypical Gpr124-and Reck-dependent Wnt/β-catenin pathway during brain angiogenesis|
B Vanhollebeke, OA Stone, N Bostaille, C Cho, Y Zhou, E Maquet, ...
elife 4, e06489, 2015
|MAGI-1 is required for Rap1 activation upon cell-cell contact and for enhancement of vascular endothelial cadherin-mediated cell adhesion|
A Sakurai, S Fukuhara, A Yamagishi, K Sako, Y Kamioka, M Masuda, ...
Molecular biology of the cell 17 (2), 966-976, 2006
|Angiopoietin-1/Tie2 signal augments basal Notch signal controlling vascular quiescence by inducing delta-like 4 expression through AKT-mediated activation of β-catenin|
J Zhang, S Fukuhara, K Sako, T Takenouchi, H Kitani, T Kume, GY Koh, ...
Journal of Biological Chemistry 286 (10), 8055-8066, 2011
|A novel dynamin-associating molecule, formin-binding protein 17, induces tubular membrane invaginations and participates in endocytosis|
Y Kamioka, S Fukuhara, H Sawa, K Nagashima, M Masuda, M Matsuda, ...
Journal of Biological Chemistry 279 (38), 40091-40099, 2004
|Enhanced functional gap junction neoformation by protein kinase A–dependent and Epac-dependent signals downstream of cAMP in cardiac myocytes|
S Somekawa, S Fukuhara, Y Nakaoka, H Fujita, Y Saito, N Mochizuki
Circulation research 97 (7), 655-662, 2005