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Ingrid Span
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Probing the reaction mechanism of IspH protein by x-ray structure analysis
T Gräwert, I Span, W Eisenreich, F Rohdich, J Eppinger, A Bacher, M Groll
Proceedings of the National Academy of Sciences 107 (3), 1077-1081, 2010
1232010
A small molecule that switches a ubiquitin ligase from a processive to a distributive enzymatic mechanism
SG Kathman, I Span, AT Smith, Z Xu, J Zhan, AC Rosenzweig, ...
Journal of the American Chemical Society 137 (39), 12442-12445, 2015
1042015
Structure of active IspH enzyme from Escherichia coli provides mechanistic insights into substrate reduction
T Gräwert, F Rohdich, I Span, A Bacher, W Eisenreich, J Eppinger, M Groll
Angewandte Chemie International Edition 48 (31), 5756-5759, 2009
932009
Time-resolved structural analysis of an RNA-cleaving DNA catalyst
J Borggräfe, J Victor, H Rosenbach, A Viegas, CGW Gertzen, C Wuebben, ...
Nature 601 (7891), 144-149, 2022
722022
Are free radicals involved in IspH catalysis? An EPR and crystallographic investigation
W Wang, K Wang, I Span, J Jauch, A Bacher, M Groll, E Oldfield
Journal of the American Chemical Society 134 (27), 11225-11234, 2012
522012
Crystal structures of mutant IspH proteins reveal a rotation of the substrate's hydroxymethyl group during catalysis
I Span, T Gräwert, A Bacher, W Eisenreich, M Groll
Journal of molecular biology 416 (1), 1-9, 2012
522012
Caught in the Hinact: Crystal Structure and Spectroscopy Reveal a Sulfur Bound to the Active Site of an O2‐stable State of [FeFe] Hydrogenase
P Rodríguez‐Maciá, LM Galle, R Bjornsson, C Lorent, I Zebger, Y Yoda, ...
Angewandte Chemie International Edition 59 (38), 16786-16794, 2020
502020
Discovery of acetylene hydratase activity of the iron–sulphur protein IspH
I Span, K Wang, W Wang, Y Zhang, A Bacher, W Eisenreich, K Li, ...
Nature communications 3 (1), 1042, 2012
482012
Asp1 Bifunctional Activity Modulates Spindle Function via Controlling Cellular Inositol Pyrophosphate Levels in Schizosaccharomyces pombe
M Pascual-Ortiz, A Saiardi, E Walla, V Jakopec, NA Künzel, I Span, ...
Molecular and Cellular Biology 38 (9), e00047-18, 2018
402018
Reductive dehydroxylation of allyl alcohols by IspH protein
T Gräwert, I Span, A Bacher, M Groll
Angewandte Chemie International Edition 49 (47), 8802-8809, 2010
362010
Structures of fluoro, amino, and thiol inhibitors bound to the [Fe4S4] protein IspH
I Span, K Wang, W Wang, J Jauch, W Eisenreich, A Bacher, E Oldfield, ...
Angewandte Chemie International Edition 52 (7), 2118-2121, 2013
312013
Insights into the binding of pyridines to the iron–sulfur enzyme IspH
I Span, K Wang, W Eisenreich, A Bacher, Y Zhang, E Oldfield, M Groll
Journal of the American Chemical Society 136 (22), 7926-7932, 2014
292014
Molecular features and metal ions that influence 10-23 DNAzyme activity
H Rosenbach, J Victor, M Etzkorn, G Steger, D Riesner, I Span
Molecules 25 (13), 3100, 2020
252020
Influence of monovalent metal ions on metal binding and catalytic activity of the 10–23 DNAzyme
H Rosenbach, J Borggräfe, J Victor, C Wuebben, O Schiemann, W Hoyer, ...
Biological chemistry 402 (1), 99-111, 2020
172020
IspH-protein von Escherichia coli–Struktur und Mechanismus
T Gräwert, F Rohdich, I Span, A Bacher, W Eisenreich, J Eppinger, M Groll
Angew Chemie 121, 5867-5870, 2009
152009
Iron-sulfur clusters are involved in post-translational arginylation
V Van, JB Brown, CR O’Shea, H Rosenbach, I Mohamed, NE Ejimogu, ...
Nature Communications 14 (1), 458, 2023
112023
Fluor‐, Amino‐und Thiolinhibitoren im Komplex mit dem [Fe4S4]‐Protein IspH
I Span, K Wang, W Wang, J Jauch, W Eisenreich, A Bacher, E Oldfield, ...
Angewandte Chemie 125 (7), 2172-2175, 2013
92013
Expanding crystallization tools for nucleic acid complexes using U1A protein variants
H Rosenbach, J Victor, J Borggräfe, R Biehl, G Steger, M Etzkorn, I Span
Journal of structural biology 210 (2), 107480, 2020
82020
Binding of exogenous cyanide reveals new active-site states in [FeFe] hydrogenases
MA Martini, K Bikbaev, Y Pang, C Lorent, C Wiemann, N Breuer, I Zebger, ...
Chemical Science 14 (11), 2826-2838, 2023
72023
Reduktive Dehydroxylierung von Allylalkoholen durch IspH‐Protein
T Gräwert, I Span, A Bacher, M Groll
Angewandte Chemie 122 (47), 8984-8991, 2010
72010
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