| Probing the reaction mechanism of IspH protein by x-ray structure analysis T Gräwert, I Span, W Eisenreich, F Rohdich, J Eppinger, A Bacher, M Groll Proceedings of the National Academy of Sciences 107 (3), 1077-1081, 2010 | 124 | 2010 |
| A small molecule that switches a ubiquitin ligase from a processive to a distributive enzymatic mechanism SG Kathman, I Span, AT Smith, Z Xu, J Zhan, AC Rosenzweig, ... Journal of the American Chemical Society 137 (39), 12442-12445, 2015 | 107 | 2015 |
| Structure of active IspH enzyme from Escherichia coli provides mechanistic insights into substrate reduction T Gräwert, F Rohdich, I Span, A Bacher, W Eisenreich, J Eppinger, M Groll Angewandte Chemie International Edition 48 (31), 5756-5759, 2009 | 93 | 2009 |
| Time-resolved structural analysis of an RNA-cleaving DNA catalyst J Borggräfe, J Victor, H Rosenbach, A Viegas, CGW Gertzen, C Wuebben, ... Nature 601 (7891), 144-149, 2022 | 85 | 2022 |
| Are free radicals involved in IspH catalysis? An EPR and crystallographic investigation W Wang, K Wang, I Span, J Jauch, A Bacher, M Groll, E Oldfield Journal of the American Chemical Society 134 (27), 11225-11234, 2012 | 53 | 2012 |
| Caught in the Hinact: Crystal Structure and Spectroscopy Reveal a Sulfur Bound to the Active Site of an O2‐stable State of [FeFe] Hydrogenase P Rodríguez‐Maciá, LM Galle, R Bjornsson, C Lorent, I Zebger, Y Yoda, ... Angewandte Chemie International Edition 59 (38), 16786-16794, 2020 | 52 | 2020 |
| Crystal structures of mutant IspH proteins reveal a rotation of the substrate's hydroxymethyl group during catalysis I Span, T Gräwert, A Bacher, W Eisenreich, M Groll Journal of molecular biology 416 (1), 1-9, 2012 | 52 | 2012 |
| Discovery of acetylene hydratase activity of the iron–sulphur protein IspH I Span, K Wang, W Wang, Y Zhang, A Bacher, W Eisenreich, K Li, ... Nature communications 3 (1), 1042, 2012 | 48 | 2012 |
| Asp1 Bifunctional Activity Modulates Spindle Function via Controlling Cellular Inositol Pyrophosphate Levels in Schizosaccharomyces pombe M Pascual-Ortiz, A Saiardi, E Walla, V Jakopec, NA Künzel, I Span, ... Molecular and Cellular Biology 38 (9), e00047-18, 2018 | 45 | 2018 |
| Reductive dehydroxylation of allyl alcohols by IspH protein T Gräwert, I Span, A Bacher, M Groll Angewandte Chemie International Edition 49 (47), 8802-8809, 2010 | 36 | 2010 |
| Structures of fluoro, amino, and thiol inhibitors bound to the [Fe4S4] protein IspH I Span, K Wang, W Wang, J Jauch, W Eisenreich, A Bacher, E Oldfield, ... Angewandte Chemie International Edition 52 (7), 2118-2121, 2013 | 31 | 2013 |
| Insights into the binding of pyridines to the iron–sulfur enzyme IspH I Span, K Wang, W Eisenreich, A Bacher, Y Zhang, E Oldfield, M Groll Journal of the American Chemical Society 136 (22), 7926-7932, 2014 | 29 | 2014 |
| Molecular features and metal ions that influence 10-23 DNAzyme activity H Rosenbach, J Victor, M Etzkorn, G Steger, D Riesner, I Span Molecules 25 (13), 3100, 2020 | 25 | 2020 |
| Influence of monovalent metal ions on metal binding and catalytic activity of the 10–23 DNAzyme H Rosenbach, J Borggräfe, J Victor, C Wuebben, O Schiemann, W Hoyer, ... Biological chemistry 402 (1), 99-111, 2020 | 17 | 2020 |
| IspH-protein von Escherichia coli–Struktur und Mechanismus T Gräwert, F Rohdich, I Span, A Bacher, W Eisenreich, J Eppinger, M Groll Angew Chemie 121, 5867-5870, 2009 | 15 | 2009 |
| Iron-sulfur clusters are involved in post-translational arginylation V Van, JB Brown, CR O’Shea, H Rosenbach, I Mohamed, NE Ejimogu, ... Nature Communications 14 (1), 458, 2023 | 14 | 2023 |
| Binding of exogenous cyanide reveals new active-site states in [FeFe] hydrogenases MA Martini, K Bikbaev, Y Pang, C Lorent, C Wiemann, N Breuer, I Zebger, ... Chemical Science 14 (11), 2826-2838, 2023 | 10 | 2023 |
| Expanding crystallization tools for nucleic acid complexes using U1A protein variants H Rosenbach, J Victor, J Borggräfe, R Biehl, G Steger, M Etzkorn, I Span Journal of structural biology 210 (2), 107480, 2020 | 9 | 2020 |
| Fluor‐, Amino‐und Thiolinhibitoren im Komplex mit dem [Fe4S4]‐Protein IspH I Span, K Wang, W Wang, J Jauch, W Eisenreich, A Bacher, E Oldfield, ... Angewandte Chemie 125 (7), 2172-2175, 2013 | 9 | 2013 |
| Reduktive Dehydroxylierung von Allylalkoholen durch IspH‐Protein T Gräwert, I Span, A Bacher, M Groll Angewandte Chemie 122 (47), 8984-8991, 2010 | 7 | 2010 |
