| Structural basis for the action of the drug trametinib at KSR-bound MEK ZM Khan, AM Real, WM Marsiglia, A Chow, ME Duffy, JR Yerabolu, ... Nature 588 (7838), 509-514, 2020 | 100 | 2020 |
| Crystallographic and Glycan Microarray Analysis of Human Polyomavirus 9 VP1 Identifies N-Glycolyl Neuraminic Acid as a Receptor Candidate ZM Khan, Y Liu, U Neu, M Gilbert, B Ehlers, T Feizi, T Stehle Journal of virology 88 (11), 6100-6111, 2014 | 51 | 2014 |
| Structures of B-lymphotropic polyomavirus VP1 in complex with oligosaccharide ligands U Neu, ZM Khan, B Schuch, AS Palma, Y Liu, M Pawlita, T Feizi, T Stehle PLoS pathogens 9 (10), e1003714, 2013 | 33 | 2013 |
| Rules and exceptions: sialic acid variants and their role in determining viral tropism T Stehle, ZM Khan Journal of virology 88 (14), 7696-7699, 2014 | 28 | 2014 |
| Type II binders targeting the “GLR-out” conformation of the pseudokinase STRADα RHB Smith, ZM Khan, PMU Ung, AP Scopton, L Silber, SM Mack, ... Biochemistry 60 (4), 289-302, 2021 | 6 | 2021 |
| Conformational control and regulation of the pseudokinase KSR via small molecule binding interactions A Chow, ZM Khan, WM Marsiglia, AC Dar Methods in enzymology 667, 365-402, 2022 | 3 | 2022 |
| WNTinib is a multi-kinase inhibitor with specificity against β-catenin mutant hepatocellular carcinoma A Rialdi, M Duffy, AP Scopton, F Fonseca, JN Zhao, M Schwarz, ... Nature Cancer 4 (8), 1157-1175, 2023 | 2 | 2023 |
| 5th International Conference on Polyomaviruses and Human Diseases: Basic and Clinical Perspectives K Khalili, D Wang, B Ehlers, ZM Khan, JA Vanchiere, J Berger, I Koralnik, ... J. Neurovirol 19, 280-309, 2013 | 1 | 2013 |
| Live-cell target engagement of allosteric MEKi on MEK–RAF/KSR–14-3-3 complexes WM Marsiglia, A Chow, ZM Khan, L He, AC Dar Nature chemical biology 20 (3), 373-381, 2024 | | 2024 |
| Small molecule modulators of ksr-bound mek A Dar, AP Scopton, JR Yerabolu, ZM Khan, AM Real, WM Marsiglia US Patent App. 17/791,364, 2023 | | 2023 |
| Live cell engagement assay A Dar, ZM Khan, WM Marsiglia US Patent App. 18/002,812, 2023 | | 2023 |
| Structural Insights into How Protein-Protein Interaction Modulates the Action of MEK Inhibitors Z Khan, W Marsiglia, A Chow, A Scopton, A Dar Microscopy and Microanalysis 27 (S1), 1716-1718, 2021 | | 2021 |
| TRAMETINIB PROMOTES MEK BINDING TO THE RAF-FAMILY PSEUDOKINASE KSR ZM Khan, AM Real, WM Marsiglia, A Chow, ME Duffy, JR Yerabolu CANCER DISCOVERY 10 (11), 1624-1624, 2020 | | 2020 |
| Structures and ligand-binding properties of major capsid proteins (VP1) of B-Lymphotropic Polyomavirus (LPyV) and Human Polyomavirus 9 (HPyV9) and Staphylococcus aureus strain … ZM Khan | | 2015 |
| Crystal structures of the major capsid protein VP1 from human polyomavirus 9 and African green monkey polyomavirus provide a foundation for understanding the serological cross … ZM Khan, U Neu, B Schuch, Y Liu, B Ehlers, M Pawlita, T Feizi, T Stehle | | 2013 |
| Structures of the major capsid protein (VP1) from closely related Human Polyomavirus-9 (HPyV-9) and African Green Monkey Polyomavirus (AGMPyV) provide insights into host range … Z Khan, U Neu, T Feizi, B Ehlers, T Stehle Cambridge University Press, 2012 | | 2012 |
| Structural insights into how the pseudokinase KSR modulates the activity of clinical MEK inhibitors ZM Khan, JR Yerabolu, AM Real, A Chow, R Smith, AP Scopton, AC Dar | | |
Thilo StehleProfessor of Biochemistry, Interfaculty Institute of Biochemistry, University of TübingenBestätigte E-Mail-Adresse bei uni-tuebingen.de
