The role of tight junctions in skin barrier function and dermal absorption K Bäsler, S Bergmann, M Heisig, A Naegel, M Zorn-Kruppa, JM Brandner Journal of Controlled Release 242, 105-118, 2016 | 256 | 2016 |
In-silico model of skin penetration based on experimentally determined input parameters. Part I: Experimental determination of partition and diffusion coefficients S Hansen, A Henning, A Naegel, M Heisig, G Wittum, D Neumann, ... European Journal of Pharmaceutics and Biopharmaceutics 68 (2), 352-367, 2008 | 123 | 2008 |
UG 4: A novel flexible software system for simulating PDE based models on high performance computers A Vogel, S Reiter, M Rupp, A Nägel, G Wittum Computing and Visualization in Science 16 (4), 165-179, 2013 | 117 | 2013 |
Detailed modeling of skin penetration—an overview A Naegel, M Heisig, G Wittum Advanced drug delivery reviews 65 (2), 191-207, 2013 | 100 | 2013 |
In-silico model of skin penetration based on experimentally determined input parameters. Part II: Mathematical modelling of in-vitro diffusion experiments. Identification of … A Naegel, S Hansen, D Neumann, CM Lehr, UF Schaefer, G Wittum, ... European journal of pharmaceutics and biopharmaceutics 68 (2), 368-379, 2008 | 87 | 2008 |
The role of corneocytes in skin transport revised—a combined computational and experimental approach S Hansen, A Naegel, M Heisig, G Wittum, D Neumann, KH Kostka, ... Pharmaceutical research 26 (6), 1379-1397, 2009 | 50 | 2009 |
A comparison of two-and three-dimensional models for the simulation of the permeability of human stratum corneum A Naegel, M Heisig, G Wittum European Journal of Pharmaceutics and Biopharmaceutics 72 (2), 332-338, 2009 | 44 | 2009 |
Effective diffusivity in membranes with tetrakaidekahedral cells and implications for the permeability of human stratum corneum I Muha, A Naegel, S Stichel, A Grillo, M Heisig, G Wittum Journal of membrane science 368 (1-2), 18-25, 2011 | 38 | 2011 |
Finite dose skin mass balance including the lateral part: comparison between experiment, pharmacokinetic modeling and diffusion models D Selzer, T Hahn, A Naegel, M Heisig, KH Kostka, CM Lehr, D Neumann, ... Journal of Controlled Release 165 (2), 119-128, 2013 | 30 | 2013 |
Numerical simulation of skin transport using Parareal A Kreienbuehl, A Naegel, D Ruprecht, R Speck, G Wittum, R Krause Computing and visualization in science 17 (2), 99-108, 2015 | 29 | 2015 |
Software Framework ug4: Parallel Multigrid on the Hermit Supercomputer I Heppner, M Lampe, A Nägel, S Reiter, M Rupp, A Vogel, G Wittum High Performance Computing in Science and Engineering ‘12, 435-449, 2013 | 26 | 2013 |
Scalable shape optimization methods for structured inverse modeling in 3D diffusive processes A Nägel, V Schulz, M Siebenborn, G Wittum Computing and Visualization in Science 17 (2), 79-88, 2015 | 25 | 2015 |
Parallel tensor sampling in the hierarchical Tucker format L Grasedyck, R Kriemann, C Löbbert, A Nägel, G Wittum, K Xylouris Computing and Visualization in Science 17 (2), 67-78, 2015 | 20 | 2015 |
Filtering algebraic multigrid and adaptive strategies A Nägel, RD Falgout, G Wittum Computing and Visualization in Science 11 (3), 159-167, 2008 | 17 | 2008 |
10,000 Performance Models per Minute–Scalability of the UG4 Simulation Framework A Vogel, A Calotoiu, A Strube, S Reiter, A Nägel, F Wolf, G Wittum European Conference on Parallel Processing, 519-531, 2015 | 16 | 2015 |
Computational Modeling of the skin barrier A Naegel, M Heisig, G Wittum Permeability Barrier, 1-32, 2011 | 16 | 2011 |
Finite dose skin penetration: a comparison of concentration-depth profiles from experiment and simulation A Naegel, T Hahn, UF Schaefer, CM Lehr, M Heisig, G Wittum Computing and Visualization in Science 14 (7), 327-339, 2011 | 14 | 2011 |
Quantitative Analysis of Hepatitis C NS5A Viral Protein Dynamics on the ER Surface MM Knodel, A Nägel, S Reiter, A Vogel, P Targett-Adams, J McLauchlan, ... Viruses 10 (1), 28, 2018 | 12 | 2018 |
Multigrid analysis of spatially resolved hepatitis C virus protein simulations MM Knodel, A Nägel, S Reiter, M Rupp, A Vogel, P Targett-Adams, ... Computing and Visualization in Science 17 (5), 235-253, 2015 | 9 | 2015 |
Towards the Implementation of a New Multigrid Solver in the DNS Code FS3D for Simulations of Shear-Thinning Jet Break-Up at Higher Reynolds Numbers M Ertl, J Reutzsch, A Nägel, G Wittum, B Weigand High Performance Computing in Science and Engineering'17, 269-287, 2018 | 8 | 2018 |