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Michelangelo Certo
Michelangelo Certo
Senior Post-doc Researcher - University of Birmingham - Queen Elizabeth Hospital
Bestätigte E-Mail-Adresse bei bham.ac.uk - Startseite
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Lactate modulation of immune responses in inflammatory versus tumour microenvironments
M Certo, CH Tsai, V Pucino, PC Ho, C Mauro
Nature Reviews Immunology 21 (3), 151-161, 2021
3812021
Lactate buildup at the site of chronic inflammation promotes disease by inducing CD4+ T cell metabolic rewiring
V Pucino, M Certo, V Bulusu, D Cucchi, K Goldmann, E Pontarini, R Haas, ...
Cell metabolism 30 (6), 1055-1074. e8, 2019
3182019
Rational modulation of the innate immune system for neuroprotection in ischemic stroke
D Amantea, G Micieli, C Tassorelli, MI Cuartero, I Ballesteros, M Certo, ...
Frontiers in neuroscience 9, 135613, 2015
2292015
Azithromycin protects mice against ischemic stroke injury by promoting macrophage transition towards M2 phenotype
D Amantea, M Certo, F Petrelli, C Tassorelli, G Micieli, MT Corasaniti, ...
Experimental neurology 275, 116-125, 2016
1092016
Activation of RXR/PPARγ underlies neuroprotection by bexarotene in ischemic stroke
M Certo, Y Endo, K Ohta, S Sakurada, G Bagetta, D Amantea
Pharmacological research 102, 298-307, 2015
712015
Understanding the multifaceted role of inflammatory mediators in ischemic stroke
D Amantea, C Tassorelli, F Petrelli, M Certo, P Bezzi, G Micieli, ...
Current Medicinal Chemistry 21 (18), 2098-2117, 2014
542014
Metabolic checkpoints in rheumatoid arthritis
V Pucino, M Certo, G Varricchi, G Marone, F Ursini, FW Rossi, A De Paulis, ...
Frontiers in physiology 11, 497106, 2020
512020
Omega-3 polyunsaturated fatty acids impinge on CD4+ T cell motility and adipose tissue distribution via direct and lipid mediator-dependent effects
D Cucchi, D Camacho-Munoz, M Certo, J Niven, J Smith, A Nicolaou, ...
Cardiovascular research 116 (5), 1006-1020, 2020
512020
Fatty acids-from energy substrates to key regulators of cell survival, proliferation and effector function
D Cucchi, D Camacho-Muñoz, M Certo, V Pucino, A Nicolaou, C Mauro
Cell Stress 4 (1), 9, 2020
442020
Endothelial cell and T‐cell crosstalk: Targeting metabolism as a therapeutic approach in chronic inflammation
M Certo, H Elkafrawy, V Pucino, D Cucchi, KCP Cheung, C Mauro
British journal of pharmacology 178 (10), 2041-2059, 2021
412021
Selective neuronal silencing using synthetic botulinum molecules alleviates chronic pain in mice
M Maiarù, C Leese, M Certo, I Echeverria-Altuna, AS Mangione, ...
Science Translational Medicine 10 (450), eaar7384, 2018
402018
Early reperfusion injury is associated to MMP2 and IL-1β elevation in cortical neurons of rats subjected to middle cerebral artery occlusion
D Amantea, M Certo, R Russo, G Bagetta, MT Corasaniti, C Tassorelli
Neuroscience 277, 755-763, 2014
392014
Lactate: fueling the fire starter
M Certo, G Marone, A de Paulis, C Mauro, V Pucino
Wiley Interdisciplinary Reviews: Systems Biology and Medicine 12 (3), e1474, 2020
362020
Understanding lactate sensing and signalling
M Certo, A Llibre, W Lee, C Mauro
Trends in Endocrinology & Metabolism 33 (10), 722-735, 2022
342022
Neuroprotective properties of a macrolide antibiotic in a mouse model of middle cerebral artery occlusion: characterization of the immunomodulatory effects and validation of …
D Amantea, M Certo, F Petrelli, G Bagetta
Assay and Drug Development Technologies 14 (5), 298-307, 2016
262016
Neuroprotection by the PARP inhibitor PJ34 modulates cerebral and circulating RAGE levels in rats exposed to focal brain ischemia
R Greco, C Tassorelli, AS Mangione, G Levandis, M Certo, G Nappi, ...
European journal of pharmacology 744, 91-97, 2014
222014
Caspase-1-independent Maturation of IL-1ββ in Ischemic Brain Injury: is there a Role for Gelatinases?
D Amantea, R Russo, M Certo, L Rombolà, A Adornetto, L A Morrone, ...
Mini reviews in medicinal chemistry 16 (9), 729-737, 2016
212016
Differential metabotypes in synovial fibroblasts and synovial fluid in hip osteoarthritis patients support inflammatory responses
H Farah, SN Wijesinghe, T Nicholson, F Alnajjar, M Certo, A Alghamdi, ...
International journal of molecular sciences 23 (6), 3266, 2022
182022
Understanding the role of host metabolites in the induction of immune senescence: Future strategies for keeping the ageing population healthy
J Conway, M Certo, JM Lord, C Mauro, NA Duggal
British journal of pharmacology 179 (9), 1808-1824, 2022
142022
Tolerogenic effects of 1, 25-dihydroxyvitamin D on dendritic cells involve induction of fatty acid synthesis
AM Garcia, EL Bishop, D Li, LE Jeffery, A Garten, A Thakker, M Certo, ...
The Journal of Steroid Biochemistry and Molecular Biology 211, 105891, 2021
132021
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