Dynamics of receptor/G protein coupling in living cells P Hein, M Frank, C Hoffmann, MJ Lohse, M Bünemann The EMBO journal 24 (23), 4106-4114, 2005 | 271 | 2005 |
Gs activation is time-limiting in initiating receptor-mediated signaling P Hein, F Rochais, C Hoffmann, S Dorsch, VO Nikolaev, S Engelhardt, ... Journal of Biological Chemistry 281 (44), 33345-33351, 2006 | 170 | 2006 |
Optical techniques to analyze real-time activation and signaling of G-protein-coupled receptors MJ Lohse, VO Nikolaev, P Hein, C Hoffmann, JP Vilardaga, M Bünemann Trends in pharmacological sciences 29 (3), 159-165, 2008 | 157 | 2008 |
Kinetics of G‐protein‐coupled receptor signals in intact cells MJ Lohse, P Hein, C Hoffmann, VO Nikolaev, JP Vilardaga, M Bünemann British journal of pharmacology 153 (S1), S125-S132, 2008 | 133 | 2008 |
Signal transduction underlying carbachol-induced contraction of rat urinary bladder. I. Phospholipases and Ca2+ sources T Schneider, P Hein, MC Michel Journal of Pharmacology and Experimental Therapeutics 308 (1), 47-53, 2004 | 101 | 2004 |
Coupling mode of receptors and G proteins P Hein, M Bünemann Naunyn-Schmiedeberg's archives of pharmacology 379, 435-443, 2009 | 72 | 2009 |
Signal transduction and regulation: Are all α1-adrenergic receptor subtypes created equal? P Hein, MC Michel Biochemical pharmacology 73 (8), 1097-1106, 2007 | 72 | 2007 |
Effects of ageing on muscarinic receptor subtypes and function in rat urinary bladder T Schneider, P Hein, MB Michel-Reher, MC Michel Naunyn-Schmiedeberg's archives of pharmacology 372, 71-78, 2005 | 59 | 2005 |
Comparison of the activation kinetics of the M3 acetylcholine receptor and a constitutively active mutant receptor in living cells C Hoffmann, S Nuber, U Zabel, N Ziegler, C Winkler, P Hein, CH Berlot, ... Molecular pharmacology 82 (2), 236-245, 2012 | 45 | 2012 |
Receptor and binding studies P Hein, MC Michel, K Leineweber, T Wieland, N Wettschureck, ... Practical methods in cardiovascular research, 723-783, 2005 | 39 | 2005 |
In vitro and in vivo uroselectivity of B8805-033, an antagonist with high affinity at prostatic α1A- vs. α1B- and α1D-adrenoceptors M Eltze, R Boer, MC Michel, P Hein, R Testa, WR Ulrich, N Kolassa, ... Naunyn-Schmiedeberg's Archives of Pharmacology 363, 649-662, 2001 | 37 | 2001 |
A role for muscarinic receptors or rho-kinase in hypertension associated rat bladder dysfunction? T Schneider, P Hein, J Bai, MC Michel The Journal of urology 173 (6), 2178-2181, 2005 | 36 | 2005 |
Comparison of signalling mechanisms involved in rat mesenteric microvessel contraction by noradrenaline and sphingosylphosphorylcholine C Altmann, V Steenpaß, P Czyborra, P Hein, MC Michel British journal of pharmacology 138 (1), 261, 2003 | 25 | 2003 |
Gαi2- and Gαi3-Specific Regulation of Voltage-Dependent L-Type Calcium Channels in Cardiomyocytes S Dizayee, S Kaestner, F Kuck, P Hein, C Klein, RP Piekorz, J Meszaros, ... PloS one 6 (9), e24979, 2011 | 23 | 2011 |
A quantitative analysis of antagonism and inverse agonism at wild-type and constitutively active hamster α1B-adrenoceptors P Hein, M Goepel, S Cotecchia, MC Michel Naunyn-Schmiedeberg's archives of pharmacology 363, 34-39, 2001 | 23 | 2001 |
Validity of the cold pressor test and pain sensitivity questionnaire via online self-administration MH McIntyre, 23andMe Research Team, A Kless, P Hein, M Field, ... PloS one 15 (4), e0231697, 2020 | 19 | 2020 |
Biochemical and histological characterisation of an experimental rodent model of non-alcoholic steatohepatitis–effects of a peroxisome proliferator-activated receptor gamma … SJ Daniels, DJ Leeming, S Detlefsen, MF Bruun, ST Hjuler, K Henriksen, ... Biomedicine & Pharmacotherapy 111, 926-933, 2019 | 17 | 2019 |
A systematic review of inverse agonism at adrenoceptor subtypes MC Michel, MB Michel-Reher, P Hein Cells 9 (9), 1923, 2020 | 15 | 2020 |
The future R&D landscape in non-alcoholic steatohepatitis (NASH) D Black, S Brockbank, S Cruwys, K Goldenstein, P Hein, B Humphries Drug discovery today 24 (2), 560-566, 2019 | 13 | 2019 |
Drug discovery and development in idiopathic pulmonary fibrosis: challenges and opportunities S Cruwys, P Hein, B Humphries, D Black Drug Discovery Today 25 (12), 2277-2283, 2020 | 11 | 2020 |