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Darrell J. Irvine
Darrell J. Irvine
Massachusetts Institute of Technology
Bestätigte E-Mail-Adresse bei mit.edu - Startseite
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Zitiert von
Zitiert von
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Reductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxia
CM Metallo, PA Gameiro, EL Bell, KR Mattaini, J Yang, K Hiller, ...
Nature 481 (7381), 380-384, 2012
17702012
Surface-structure-regulated cell-membrane penetration by monolayer-protected nanoparticles
A Verma, O Uzun, Y Hu, Y Hu, HS Han, N Watson, S Chen, DJ Irvine, ...
Nature materials 7 (7), 588-595, 2008
13722008
Bio-inspired, bioengineered and biomimetic drug delivery carriers
JW Yoo, DJ Irvine, DE Discher, S Mitragotri
Nature reviews Drug discovery 10 (7), 521-535, 2011
11692011
Direct observation of ligand recognition by T cells
DJ Irvine, MA Purbhoo, M Krogsgaard, MM Davis
Nature 419 (6909), 845-849, 2002
9722002
Structure-based programming of lymph-node targeting in molecular vaccines
H Liu, KD Moynihan, Y Zheng, GL Szeto, AV Li, B Huang, DS Van Egeren, ...
Nature 507 (7493), 519-522, 2014
7762014
Therapeutic cell engineering with surface-conjugated synthetic nanoparticles
MT Stephan, JJ Moon, SH Um, A Bershteyn, DJ Irvine
Nature medicine 16 (9), 1035-1041, 2010
6852010
Synthetic nanoparticles for vaccines and immunotherapy
DJ Irvine, MC Hanson, K Rakhra, T Tokatlian
Chemical reviews 115 (19), 11109-11146, 2015
6832015
T cell killing does not require the formation of a stable mature immunological synapse
MA Purbhoo, DJ Irvine, JB Huppa, MM Davis
Nature immunology 5 (5), 524-530, 2004
6222004
Interbilayer-crosslinked multilamellar vesicles as synthetic vaccines for potent humoral and cellular immune responses
JJ Moon, H Suh, A Bershteyn, MT Stephan, H Liu, B Huang, M Sohail, ...
Nature materials 10 (3), 243-251, 2011
5682011
Engineering synthetic vaccines using cues from natural immunity
DJ Irvine, MA Swartz, GL Szeto
Nature materials 12 (11), 978-990, 2013
5322013
Co-regulation of cell adhesion by nanoscale RGD organization and mechanical stimulus
LY Koo, DJ Irvine, AM Mayes, DA Lauffenburger, LG Griffith
Journal of cell science 115 (7), 1423-1433, 2002
4972002
Eradication of large established tumors in mice by combination immunotherapy that engages innate and adaptive immune responses
KD Moynihan, CF Opel, GL Szeto, A Tzeng, EF Zhu, JM Engreitz, ...
Nature medicine 22 (12), 1402-1410, 2016
4682016
Enhancing cancer immunotherapy with nanomedicine
DJ Irvine, EL Dane
Nature Reviews Immunology 20 (5), 321-334, 2020
4272020
Enhancing T cell therapy through TCR-signaling-responsive nanoparticle drug delivery
L Tang, Y Zheng, MB Melo, L Mabardi, AP Castaño, YQ Xie, N Li, ...
Nature biotechnology 36 (8), 707-716, 2018
4232018
Engineering nano‐and microparticles to tune immunity
JJ Moon, B Huang, DJ Irvine
Advanced materials 24 (28), 3724-3746, 2012
4162012
A robust, high-throughput assay to determine the phagocytic activity of clinical antibody samples
ME Ackerman, B Moldt, RT Wyatt, AS Dugast, E McAndrew, S Tsoukas, ...
Journal of immunological methods 366 (1-2), 8-19, 2011
3822011
Enhancing humoral responses to a malaria antigen with nanoparticle vaccines that expand Tfh cells and promote germinal center induction
JJ Moon, H Suh, AV Li, CF Ockenhouse, A Yadava, DJ Irvine
Proceedings of the National Academy of Sciences 109 (4), 1080-1085, 2012
3642012
In Vitro and in Vivo mRNA Delivery Using Lipid-Enveloped pH-Responsive Polymer Nanoparticles
X Su, J Fricke, DG Kavanagh, DJ Irvine
Molecular pharmaceutics 8 (3), 774-787, 2011
3412011
T cell-targeting nanoparticles focus delivery of immunotherapy to improve antitumor immunity
D Schmid, CG Park, CA Hartl, N Subedi, AN Cartwright, RB Puerto, ...
Nature communications 8 (1), 1747, 2017
3372017
HIV vaccine design to target germline precursors of glycan-dependent broadly neutralizing antibodies
JM Steichen, DW Kulp, T Tokatlian, A Escolano, P Dosenovic, ...
Immunity 45 (3), 483-496, 2016
3362016
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