The ectodomain of Toll-like receptor 9 is cleaved to generate a functional receptor SE Ewald, BL Lee, L Lau, KE Wickliffe, GP Shi, HA Chapman, GM Barton Nature 456 (7222), 658-662, 2008 | 731 | 2008 |
Nucleic acid recognition by the innate immune system R Barbalat, SE Ewald, ML Mouchess, GM Barton Annual review of immunology 29, 185-214, 2011 | 688 | 2011 |
Nucleic acid recognition by Toll-like receptors is coupled to stepwise processing by cathepsins and asparagine endopeptidase SE Ewald, A Engel, J Lee, M Wang, M Bogyo, GM Barton Journal of Experimental Medicine 208 (4), 643-651, 2011 | 355 | 2011 |
NLRP1 is an inflammasome sensor for Toxoplasma gondii SE Ewald, J Chavarria-Smith, JC Boothroyd Infection and immunity 82 (1), 460-468, 2014 | 274 | 2014 |
Toxoplasma Effector MAF1 Mediates Recruitment of Host Mitochondria and Impacts the Host Response L Pernas, Y Adomako-Ankomah, AJ Shastri, SE Ewald, M Treeck, ... PLoS biology 12 (4), e1001845, 2014 | 194 | 2014 |
Transmembrane mutations in Toll-like receptor 9 bypass the requirement for ectodomain proteolysis and induce fatal inflammation ML Mouchess, N Arpaia, G Souza, R Barbalat, SE Ewald, L Lau, ... Immunity 35 (5), 721-732, 2011 | 125 | 2011 |
Immunoregulatory role of NK cells in tissue inflammation and regeneration A Tosello-Trampont, FA Surette, SE Ewald, YS Hahn Frontiers in immunology 8, 301, 2017 | 118 | 2017 |
Nucleic acid sensing Toll-like receptors in autoimmunity SE Ewald, GM Barton Current opinion in immunology 23 (1), 3-9, 2011 | 86 | 2011 |
The molecular biology and immune control of chronic Toxoplasma gondii infection XY Zhao, SE Ewald The Journal of clinical investigation 130 (7), 3370-3380, 2020 | 76 | 2020 |
Toxoplasma gondii infection triggers chronic cachexia and sustained commensal dysbiosis in mice JA Hatter, YM Kouche, SJ Melchor, K Ng, DM Bouley, JC Boothroyd, ... PloS one 13 (10), e0204895, 2018 | 54 | 2018 |
Disease Tolerance in Toxoplasma Infection SJ Melchor, SE Ewald Frontiers in Cellular and Infection Microbiology 9, 185, 2019 | 42 | 2019 |
IL-1R regulates disease tolerance and cachexia in Toxoplasma gondii infection SJ Melchor, CM Saunders, I Sanders, JA Hatter, KA Byrnes, ... The Journal of Immunology 204 (12), 3329-3338, 2020 | 26 | 2020 |
The myeloid receptor PILRβ mediates the balance of inflammatory responses through regulation of IL-27 production CM Tato, B Joyce-Shaikh, A Banerjee, Y Chen, M Sathe, SE Ewald, ... PloS one 7 (3), e31680, 2012 | 22 | 2012 |
Automated spatially targeted optical microproteomics (autoSTOMP) to determine protein complexity of subcellular structures B Yin, R Mendez, XY Zhao, R Rakhit, KL Hsu, SE Ewald Analytical chemistry 92 (2), 2005-2010, 2019 | 15 | 2019 |
Phosphorylation of Toxoplasma gondii Secreted Proteins during Acute and Chronic Stages of Infection JC Young, M Broncel, H Teague, MRG Russell, OL McGovern, ... MSphere 5 (5), 10.1128/msphere. 00792-20, 2020 | 12 | 2020 |
Reduced mitochondrial calcium uptake in macrophages is a major driver of inflammaging PV Seegren, LR Harper, TK Downs, XY Zhao, SB Viswanathan, ... Nature Aging 3 (7), 796-812, 2023 | 9 | 2023 |
T. gondii infection induces IL-1R dependent chronic cachexia and perivascular fibrosis in the liver and skeletal muscle SJ Melchor, JA Hatter, ÉALT Castillo, CM Saunders, KA Byrnes, I Sanders, ... Scientific reports 10 (1), 15724, 2020 | 9 | 2020 |
Cellular barcoding of protozoan pathogens reveals the within-host population dynamics of Toxoplasma gondii host colonization CJ Wincott, G Sritharan, HJ Benns, D May, C Gilabert-Carbajo, M Bunyan, ... Cell Reports Methods 2 (8), 2022 | 8 | 2022 |
Automated Spatially Targeted Optical Microproteomics Investigates Inflammatory Lesions In Situ B Yin, LR Caggiano, RC Li, E McGowan, JW Holmes, SE Ewald Journal of proteome research 20 (9), 4543-4552, 2021 | 5 | 2021 |
Microbial pathogenesis in the era of spatial omics S Lempke, D May, SE Ewald Infection and Immunity 91 (7), e00442-22, 2023 | 4 | 2023 |