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Sarah E Ewald
Sarah E Ewald
Associate Professor of Microbiology, Immunology and Cancer Biology
Bestätigte E-Mail-Adresse bei virginia.edu
Titel
Zitiert von
Zitiert von
Jahr
The ectodomain of Toll-like receptor 9 is cleaved to generate a functional receptor
SE Ewald, BL Lee, L Lau, KE Wickliffe, GP Shi, HA Chapman, GM Barton
Nature 456 (7222), 658-662, 2008
7312008
Nucleic acid recognition by the innate immune system
R Barbalat, SE Ewald, ML Mouchess, GM Barton
Annual review of immunology 29, 185-214, 2011
6882011
Nucleic acid recognition by Toll-like receptors is coupled to stepwise processing by cathepsins and asparagine endopeptidase
SE Ewald, A Engel, J Lee, M Wang, M Bogyo, GM Barton
Journal of Experimental Medicine 208 (4), 643-651, 2011
3552011
NLRP1 is an inflammasome sensor for Toxoplasma gondii
SE Ewald, J Chavarria-Smith, JC Boothroyd
Infection and immunity 82 (1), 460-468, 2014
2742014
Toxoplasma Effector MAF1 Mediates Recruitment of Host Mitochondria and Impacts the Host Response
L Pernas, Y Adomako-Ankomah, AJ Shastri, SE Ewald, M Treeck, ...
PLoS biology 12 (4), e1001845, 2014
1942014
Transmembrane mutations in Toll-like receptor 9 bypass the requirement for ectodomain proteolysis and induce fatal inflammation
ML Mouchess, N Arpaia, G Souza, R Barbalat, SE Ewald, L Lau, ...
Immunity 35 (5), 721-732, 2011
1252011
Immunoregulatory role of NK cells in tissue inflammation and regeneration
A Tosello-Trampont, FA Surette, SE Ewald, YS Hahn
Frontiers in immunology 8, 301, 2017
1182017
Nucleic acid sensing Toll-like receptors in autoimmunity
SE Ewald, GM Barton
Current opinion in immunology 23 (1), 3-9, 2011
862011
The molecular biology and immune control of chronic Toxoplasma gondii infection
XY Zhao, SE Ewald
The Journal of clinical investigation 130 (7), 3370-3380, 2020
762020
Toxoplasma gondii infection triggers chronic cachexia and sustained commensal dysbiosis in mice
JA Hatter, YM Kouche, SJ Melchor, K Ng, DM Bouley, JC Boothroyd, ...
PloS one 13 (10), e0204895, 2018
542018
Disease Tolerance in Toxoplasma Infection
SJ Melchor, SE Ewald
Frontiers in Cellular and Infection Microbiology 9, 185, 2019
422019
IL-1R regulates disease tolerance and cachexia in Toxoplasma gondii infection
SJ Melchor, CM Saunders, I Sanders, JA Hatter, KA Byrnes, ...
The Journal of Immunology 204 (12), 3329-3338, 2020
262020
The myeloid receptor PILRβ mediates the balance of inflammatory responses through regulation of IL-27 production
CM Tato, B Joyce-Shaikh, A Banerjee, Y Chen, M Sathe, SE Ewald, ...
PloS one 7 (3), e31680, 2012
222012
Automated spatially targeted optical microproteomics (autoSTOMP) to determine protein complexity of subcellular structures
B Yin, R Mendez, XY Zhao, R Rakhit, KL Hsu, SE Ewald
Analytical chemistry 92 (2), 2005-2010, 2019
152019
Phosphorylation of Toxoplasma gondii Secreted Proteins during Acute and Chronic Stages of Infection
JC Young, M Broncel, H Teague, MRG Russell, OL McGovern, ...
MSphere 5 (5), 10.1128/msphere. 00792-20, 2020
122020
Reduced mitochondrial calcium uptake in macrophages is a major driver of inflammaging
PV Seegren, LR Harper, TK Downs, XY Zhao, SB Viswanathan, ...
Nature Aging 3 (7), 796-812, 2023
92023
T. gondii infection induces IL-1R dependent chronic cachexia and perivascular fibrosis in the liver and skeletal muscle
SJ Melchor, JA Hatter, ÉALT Castillo, CM Saunders, KA Byrnes, I Sanders, ...
Scientific reports 10 (1), 15724, 2020
92020
Cellular barcoding of protozoan pathogens reveals the within-host population dynamics of Toxoplasma gondii host colonization
CJ Wincott, G Sritharan, HJ Benns, D May, C Gilabert-Carbajo, M Bunyan, ...
Cell Reports Methods 2 (8), 2022
82022
Automated Spatially Targeted Optical Microproteomics Investigates Inflammatory Lesions In Situ
B Yin, LR Caggiano, RC Li, E McGowan, JW Holmes, SE Ewald
Journal of proteome research 20 (9), 4543-4552, 2021
52021
Microbial pathogenesis in the era of spatial omics
S Lempke, D May, SE Ewald
Infection and Immunity 91 (7), e00442-22, 2023
42023
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