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Luke Gilbert
Luke Gilbert
Core Investigator at Arc Institute and Associate Professor at UCSF
Verified email at ucsf.edu
Title
Cited by
Cited by
Year
Repurposing CRISPR as an RNA-guided platform for sequence-specific control of gene expression
LS Qi, MH Larson, LA Gilbert, JA Doudna, JS Weissman, AP Arkin, ...
Cell 152 (5), 1173-1183, 2013
54482013
CRISPR-mediated modular RNA-guided regulation of transcription in eukaryotes
LA Gilbert, MH Larson, L Morsut, Z Liu, GA Brar, SE Torres, ...
Cell 154 (2), 442-451, 2013
40812013
Genome-scale CRISPR-mediated control of gene repression and activation
LA Gilbert, MA Horlbeck, B Adamson, JE Villalta, Y Chen, EH Whitehead, ...
Cell 159 (3), 647-661, 2014
26652014
Dynamic imaging of genomic loci in living human cells by an optimized CRISPR/Cas system
B Chen, LA Gilbert, BA Cimini, J Schnitzbauer, W Zhang, GW Li, J Park, ...
Cell 155 (7), 1479-1491, 2013
21312013
A protein-tagging system for signal amplification in gene expression and fluorescence imaging
ME Tanenbaum, LA Gilbert, LS Qi, JS Weissman, RD Vale
Cell 159 (3), 635-646, 2014
15522014
CRISPR interference (CRISPRi) for sequence-specific control of gene expression
MH Larson, LA Gilbert, X Wang, WA Lim, JS Weissman, LS Qi
Nature protocols 8 (11), 2180-2196, 2013
13252013
Engineering complex synthetic transcriptional programs with CRISPR RNA scaffolds
JG Zalatan, ME Lee, R Almeida, LA Gilbert, EH Whitehead, M La Russa, ...
Cell 160 (1), 339-350, 2015
10542015
A multiplexed single-cell CRISPR screening platform enables systematic dissection of the unfolded protein response
B Adamson, TM Norman, M Jost, MY Cho, JK Nuñez, Y Chen, JE Villalta, ...
Cell 167 (7), 1867-1882. e21, 2016
9442016
CRISPRi-based genome-scale identification of functional long noncoding RNA loci in human cells
SJ Liu, MA Horlbeck, SW Cho, HS Birk, M Malatesta, D He, FJ Attenello, ...
Science 355 (6320), eaah7111, 2017
6982017
Compact and highly active next-generation libraries for CRISPR-mediated gene repression and activation
MA Horlbeck, LA Gilbert, JE Villalta, B Adamson, RA Pak, Y Chen, ...
elife 5, e19760, 2016
6842016
Genomic hallmarks and structural variation in metastatic prostate cancer
DA Quigley, HX Dang, SG Zhao, P Lloyd, R Aggarwal, JJ Alumkal, A Foye, ...
Cell 174 (3), 758-769. e9, 2018
6142018
CRISPR interference efficiently induces specific and reversible gene silencing in human iPSCs
MA Mandegar, N Huebsch, EB Frolov, E Shin, A Truong, MP Olvera, ...
Cell stem cell 18 (4), 541-553, 2016
5152016
DNA damage-mediated induction of a chemoresistant niche
LA Gilbert, MT Hemann
Cell 143 (3), 355-366, 2010
4982010
Nucleosomes impede Cas9 access to DNA in vivo and in vitro
MA Horlbeck, LB Witkowsky, B Guglielmi, JM Replogle, LA Gilbert, ...
elife 5, e12677, 2016
4182016
Versatile protein tagging in cells with split fluorescent protein
D Kamiyama, S Sekine, B Barsi-Rhyne, J Hu, B Chen, LA Gilbert, ...
Nature communications 7 (1), 11046, 2016
4002016
Genome-wide programmable transcriptional memory by CRISPR-based epigenome editing
JK Nuñez, J Chen, GC Pommier, JZ Cogan, JM Replogle, C Adriaens, ...
Cell 184 (9), 2503-2519. e17, 2021
3392021
Mapping the genetic landscape of human cells
MA Horlbeck, A Xu, M Wang, NK Bennett, CY Park, D Bogdanoff, ...
Cell 174 (4), 953-967. e22, 2018
2452018
Combined CRISPRi/a-based chemical genetic screens reveal that rigosertib is a microtubule-destabilizing agent
M Jost, Y Chen, LA Gilbert, MA Horlbeck, L Krenning, G Menchon, A Rai, ...
Molecular cell 68 (1), 210-223. e6, 2017
2182017
Toxoplasma gondii Targets a Protein Phosphatase 2C to the Nuclei of Infected Host Cells
LA Gilbert, S Ravindran, JM Turetzky, JC Boothroyd, PJ Bradley
Eukaryotic cell 6 (1), 73-83, 2007
2182007
The DNA methylation landscape of advanced prostate cancer
SG Zhao, WS Chen, H Li, A Foye, M Zhang, M Sjöström, R Aggarwal, ...
Nature genetics 52 (8), 778-789, 2020
2142020
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