In Vitro and in Vivo Evaluation of 11C-Labeled Azetidinecarboxylates for Imaging Monoacylglycerol Lipase by PET Imaging Studies R Cheng, W Mori, L Ma, M Alhouayek, A Hatori, Y Zhang, D Ogasawara, ... Journal of medicinal chemistry 61 (6), 2278-2291, 2018 | 38 | 2018 |
Metal-free 18F-labeling of aryl-CF2H via nucleophilic radiofluorination and oxidative C–H activation G Yuan, F Wang, NA Stephenson, L Wang, BH Rotstein, N Vasdev, ... Chemical Communications 53 (1), 126-129, 2016 | 29 | 2016 |
Novel radioligands for imaging sigma-1 receptor in brain using positron emission tomography (PET) CW Y Lan, P Bai, Z Chen, R Neelamegam, MS Placzek, H Wang, SA Fiedler, J ... Acta Pharmaceutica Sinica B, 2019 | 21 | 2019 |
Towards next generation adenosine A2A receptor antagonists G Yuan, GB Jones Current Medicinal Chemistry 21 (34), 3918-3935, 2014 | 21 | 2014 |
Radiosynthesis and preliminary PET evaluation of 18F-labeled 2-(1-(3-fluorophenyl)-2-oxo-5-(pyrimidin-2-yl)-1, 2-dihydropyridin-3-yl) benzonitrile for imaging AMPA receptors G Yuan, GB Jones, N Vasdev, SH Liang Bioorganic & medicinal chemistry letters 26 (19), 4857-4860, 2016 | 20 | 2016 |
Novel approaches for targeting the adenosine A2A receptor G Yuan, NG Gedeon, TC Jankins, GB Jones Expert Opinion on Drug Discovery 10 (1), 63-80, 2015 | 15 | 2015 |
Discovery of carbon-11 labeled sulfonamide derivative: A PET tracer for imaging brain NLRP3 inflammasome Y Xu, Y Xu, H Blevins, Y Lan, Y Liu, G Yuan, R Striar, JS Zagaroli, ... Bioorganic & medicinal chemistry letters 34, 127777, 2021 | 14 | 2021 |
A concise method for fully automated radiosyntheses of [18 F] JNJ-46356479 and [18 F] FITM via Cu-mediated 18 F-fluorination of organoboranes G Yuan, TM Shoup, SH Moon, AL Brownell RSC advances 10 (42), 25223-25227, 2020 | 14 | 2020 |
Design, synthesis, and evaluation of thienodiazepine derivatives as positron emission tomography imaging probes for bromodomain and extra-terminal domain family proteins P Bai, Y Lan, D Patnaik, H Wang, Y Liu, Z Chen, G Yuan, S Afshar, ... Journal of Medicinal Chemistry 64 (19), 14745-14756, 2021 | 12 | 2021 |
Imaging assisted evaluation of antitumor efficacy of a new histone deacetylase inhibitor in the castration-resistant prostate cancer Z Chen, X Wang, X Yang, Y Xu, Y Yang, H Wang, T Li, P Bai, G Yuan, ... European Journal of Nuclear Medicine and Molecular Imaging 48, 53-66, 2021 | 12 | 2021 |
Fluorinated adenosine A2A receptor antagonists inspired by preladenant as potential cancer immunotherapeutics G Yuan, TC Jankins, CG Patrick Jr, P Philbrook, O Sears, S Hatfield, ... International Journal of Medicinal Chemistry 2017, 2017 | 11 | 2017 |
Synthesis and Characterization of [18F]JNJ-46356479 as the First 18F-Labeled PET Imaging Ligand for Metabotropic Glutamate Receptor 2 G Yuan, NJ Guehl, B Zheng, X Qu, SH Moon, M Dhaynaut, TM Shoup, ... Molecular imaging and biology 23, 527-536, 2021 | 9 | 2021 |
Synthesis and characterization of a positron emission tomography imaging probe selectively targeting the second bromodomain of bromodomain protein BRD4 P Bai, Y Lan, H Wang, Y Liu, R Striar, G Yuan, S Afshar, JS Zagaroli, ... Bioconjugate Chemistry 32 (8), 1711-1718, 2021 | 7 | 2021 |
Synthesis and characterization of a new Positron emission tomography probe for orexin 2 receptors neuroimaging P Bai, Y Liu, Y Xu, R Striar, G Yuan, S Afshar, AG Langan, AK Rattray, ... Bioorganic chemistry 123, 105779, 2022 | 6 | 2022 |
Design, synthesis, and characterization of benzimidazole derivatives as positron emission tomography imaging ligands for metabotropic glutamate receptor 2 G Yuan, X Qu, B Zheng, R Neelamegam, S Afshar, S Iyengar, C Pan, ... Journal of Medicinal Chemistry 63 (20), 12060-12072, 2020 | 6 | 2020 |
Synthesis and Characterization of Fluorine-18-Labeled N-(4-Chloro-3-((fluoromethyl-d2)thio)phenyl)picolinamide for Imaging of mGluR4 in Brain J Wang, X Qu, TM Shoup, G Yuan, S Afshar, C Pan, A Zhu, JK Choi, ... Journal of medicinal chemistry 63 (6), 3381-3389, 2020 | 6 | 2020 |
Design, Synthesis, and Characterization of [18F]mG2P026 as a High-Contrast PET Imaging Ligand for Metabotropic Glutamate Receptor 2 G Yuan, M Dhaynaut, NJ Guehl, S Afshar, D Huynh, SH Moon, ... Journal of medicinal chemistry 65 (14), 9939-9954, 2022 | 5 | 2022 |
PET imaging studies to investigate functional expression of mGluR2 using [11C]mG2P001 G Yuan, M Dhaynaut, NJ Guehl, R Neelamegam, SH Moon, X Qu, ... Journal of Cerebral Blood Flow & Metabolism 43 (2), 296-308, 2023 | 4 | 2023 |
Longitudinal PET studies of mGluR5 in FXS using an FMR1 knockout mouse model S Afshar, S Lule, G Yuan, X Qu, C Pan, M Whalen, AL Brownell, M Mody Translational Neuroscience 13 (1), 80-92, 2022 | 4 | 2022 |
Synthesis and Characterization of 5-(2-Fluoro-4-[11C]methoxyphenyl)-2,2-dimethyl-3,4-dihydro-2H-pyrano[2,3-b]pyridine-7-carboxamide as a PET Imaging … G Yuan, M Dhaynaut, Y Lan, NJ Guehl, D Huynh, SM Iyengar, S Afshar, ... Journal of medicinal chemistry 65 (3), 2593-2609, 2022 | 4 | 2022 |