Muscle weakness in myotonic dystrophy associated with misregulated splicing and altered gating of CaV1.1 calcium channel ZZ Tang, V Yarotskyy, L Wei, K Sobczak, M Nakamori, K Eichinger, ... Human molecular genetics 21 (6), 1312-1324, 2012 | 192 | 2012 |
AICAR prevents heat-induced sudden death in RyR1 mutant mice independent of AMPK activation JT Lanner, DK Georgiou, A Dagnino-Acosta, A Ainbinder, Q Cheng, ... Nature medicine 18 (2), 244-251, 2012 | 129 | 2012 |
The Timothy syndrome mutation of cardiac CaV1. 2 (L‐type) channels: multiple altered gating mechanisms and pharmacological restoration of inactivation V Yarotskyy, G Gao, BZ Peterson, KS Elmslie The Journal of physiology 587 (3), 551-565, 2009 | 97 | 2009 |
Spontaneously active and InsP3‐activated ion channels in cell nuclei from rat cerebellar Purkinje and granule neurones SM Marchenko, VV Yarotskyy, TN Kovalenko, PG Kostyuk, RC Thomas The Journal of physiology 565 (3), 897-910, 2005 | 94 | 2005 |
Site-specific effects of diselenide bridges on the oxidative folding of a cystine knot peptide, ω-selenoconotoxin GVIA KH Gowd, V Yarotskyy, KS Elmslie, JJ Skalicky, BM Olivera, G Bulaj Biochemistry 49 (12), 2741-2752, 2010 | 62 | 2010 |
Congenital myopathy results from misregulation of a muscle Ca2+ channel by mutant Stac3 JW Linsley, IU Hsu, L Groom, V Yarotskyy, M Lavorato, EJ Horstick, ... Proceedings of the National Academy of Sciences 114 (2), E228-E236, 2017 | 57 | 2017 |
Roscovitine, a cyclin‐dependent kinase inhibitor, affects several gating mechanisms to inhibit cardiac L‐type (Ca(V)1.2) calcium channels V Yarotskyy, KS Elmslie British journal of pharmacology 152 (3), 386-395, 2007 | 57 | 2007 |
Ca2+ permeation and/or binding to CaV1.1 fine-tunes skeletal muscle Ca2+ signaling to sustain muscle function CS Lee, A Dagnino-Acosta, V Yarotskyy, A Hanna, A Lyfenko, ... Skeletal muscle 5, 1-16, 2015 | 51 | 2015 |
Phospholemman modulates the gating of cardiac L-type calcium channels X Wang, G Gao, K Guo, V Yarotskyy, C Huang, KS Elmslie, BZ Peterson Biophysical journal 98 (7), 1149-1159, 2010 | 50 | 2010 |
Accelerated activation of SOCE current in myotubes from two mouse models of anesthetic-and heat-induced sudden death V Yarotskyy, F Protasi, RT Dirksen PLoS One 8 (10), e77633, 2013 | 43 | 2013 |
Temperature and RyR1 regulate the activation rate of store-operated Ca2+ entry current in myotubes V Yarotskyy, RT Dirksen Biophysical journal 103 (2), 202-211, 2012 | 41 | 2012 |
Roscovitine binds to novel L-channel (CaV1. 2) sites that separately affect activation and inactivation V Yarotskyy, G Gao, L Du, SB Ganapathi, BZ Peterson, KS Elmslie Journal of biological chemistry 285 (1), 43-53, 2010 | 38 | 2010 |
The intravenous anesthetic propofol inhibits human L‐type calcium channels by enhancing voltage‐dependent inactivation J Fassl, KM High, ER Stephenson, V Yarotskyy, KS Elmslie The Journal of Clinical Pharmacology 51 (5), 719-730, 2011 | 37 | 2011 |
The large-conductance ion channels in the nuclear envelope of central neurons O Fedorenko, V Yarotskyy, D Duzhyy, S Marchenko Pflügers Archiv-European Journal of Physiology 460, 1045-1050, 2010 | 30 | 2010 |
ω-Conotoxin GVIA alters gating charge movement of N-type (CaV2. 2) calcium channels V Yarotskyy, KS Elmslie Journal of neurophysiology 101 (1), 332-340, 2009 | 28 | 2009 |
HIV-1 Tat and morphine differentially disrupt pyramidal cell structure and function and spatial learning in hippocampal area CA1: continuous versus interrupted morphine exposure WD Marks, JJ Paris, AJ Barbour, J Moon, VJ Carpenter, VD McLane, ... Eneuro 8 (3), 2021 | 19 | 2021 |
Roscovitine inhibits CaV3. 1 (T-type) channels by preferentially affecting closed-state inactivation V Yarotskyy, KS Elmslie Journal of Pharmacology and Experimental Therapeutics 340 (2), 463-472, 2012 | 14 | 2012 |
Interference between two modulators of N-type (CaV2. 2) calcium channel gating demonstrates that ω-conotoxin GVIA disrupts open state gating V Yarotskyy, KS Elmslie Biochimica et Biophysica Acta (BBA)-Biomembranes 1798 (9), 1821-1828, 2010 | 12 | 2010 |
Methods and Materials for Treating Mental Illness AE Martynyuk, DM Dennis, N Gravenstein, AV Glushakov, V Yarotskyy, ... US Patent App. 11/572,275, 2008 | 11 | 2008 |
Differential modulation of glutamatergic transmission by 3, 5-dibromo-L-phenylalanine V Yarotskyy, AV Glushakov, C Sumners, N Gravenstein, DM Dennis, ... Molecular pharmacology 67 (5), 1648-1654, 2005 | 11 | 2005 |