Volker Hovestadt
Volker Hovestadt
MGH & Broad Institute
Bestätigte E-Mail-Adresse bei broadinstitute.org - Startseite
TitelZitiert vonJahr
Driver mutations in histone H3. 3 and chromatin remodelling genes in paediatric glioblastoma
J Schwartzentruber, A Korshunov, XY Liu, DTW Jones, E Pfaff, K Jacob, ...
Nature 482 (7384), 226-231, 2012
12642012
Hotspot Mutations in H3F3A and IDH1 Define Distinct Epigenetic and Biological Subgroups of Glioblastoma
D Sturm, H Witt, V Hovestadt, DA Khuong-Quang, DTW Jones, ...
Cancer Cell 22 (4), 425-437, 2012
9312012
Dissecting the genomic complexity underlying medulloblastoma
DTW Jones, N Jäger, M Kool, T Zichner, B Hutter, M Sultan, YJ Cho, ...
Nature 488 (7409), 100-105, 2012
5932012
Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma
DTW Jones, B Hutter, N Jäger, A Korshunov, M Kool, HJ Warnatz, ...
Nature genetics 45 (8), 927-932, 2013
3782013
Epigenomic alterations define lethal CIMP-positive ependymomas of infancy
SC Mack, H Witt, RM Piro, L Gu, S Zuyderduyn, AM Stütz, X Wang, ...
Nature 506 (7489), 445-450, 2014
3292014
Genome sequencing of SHH medulloblastoma predicts genotype-related response to smoothened inhibition
M Kool, DTW Jones, N Jäger, PA Northcott, TJ Pugh, V Hovestadt, ...
Cancer cell 25 (3), 393-405, 2014
3282014
Molecular Classification of Ependymal Tumors across All CNS Compartments, Histopathological Grades, and Age Groups
KW Pajtler, H Witt, M Sill, DTW Jones, V Hovestadt, F Kratochwil, K Wani, ...
Cancer Cell 27 (5), 728-743, 2015
3172015
MicroRNA sequence and expression analysis in breast tumors by deep sequencing
TA Farazi, HM Horlings, J Jelle, A Mihailovic, H Halfwerk, P Morozov, ...
Cancer research 71 (13), 4443-4453, 2011
3132011
Reduced H3K27me3 and DNA hypomethylation are major drivers of gene expression in K27M mutant pediatric high-grade gliomas
S Bender, Y Tang, AM Lindroth, V Hovestadt, DTW Jones, M Kool, ...
Cancer cell 24 (5), 660-672, 2013
2822013
ATRX and IDH1-R132H immunohistochemistry with subsequent copy number analysis and IDH sequencing as a basis for an “integrated” diagnostic approach for adult astrocytoma …
DE Reuss, F Sahm, D Schrimpf, B Wiestler, D Capper, C Koelsche, ...
Acta neuropathologica 129 (1), 133-146, 2015
2512015
Recurrent mutation of the ID3 gene in Burkitt lymphoma identified by integrated genome, exome and transcriptome sequencing.
J Richter, M Schlesner, S Hoffmann, M Kreuz, E Leich, B Burkhardt, ...
Nature genetics, 2012
2512012
Enhancer hijacking activates GFI1 family oncogenes in medulloblastoma
PA Northcott, C Lee, T Zichner, AM Stütz, S Erkek, D Kawauchi, DJH Shih, ...
Nature 511 (7510), 428-434, 2014
2262014
Decoding the regulatory landscape of medulloblastoma using DNA methylation sequencing
V Hovestadt, DTW Jones, S Picelli, W Wang, M Kool, PA Northcott, ...
Nature 510 (7506), 537-541, 2014
2122014
New Brain Tumor Entities Emerge from Molecular Classification of CNS-PNETs
D Sturm, BA Orr, UH Toprak, V Hovestadt, DTW Jones, D Capper, M Sill, ...
Cell 164 (5), 1060-1072, 2016
2082016
BCAT1 promotes cell proliferation through amino acid catabolism in gliomas carrying wild-type IDH1
M Tönjes, S Barbus, YJ Park, W Wang, M Schlotter, AM Lindroth, ...
Nature medicine 19 (7), 901-908, 2013
1692013
Integrated analysis of pediatric glioblastoma reveals a subset of biologically favorable tumors with associated molecular prognostic markers
A Korshunov, M Ryzhova, V Hovestadt, S Bender, D Sturm, D Capper, ...
Acta neuropathologica 129 (5), 669-678, 2015
1442015
Robust molecular subgrouping and copy-number profiling of medulloblastoma from small amounts of archival tumour material using high-density DNA methylation arrays
V Hovestadt, M Remke, M Kool, T Pietsch, PA Northcott, R Fischer, ...
Acta neuropathologica 125 (6), 913-916, 2013
1432013
Atypical Teratoid/Rhabdoid Tumors Are Comprised of Three Epigenetic Subgroups with Distinct Enhancer Landscapes
PD Johann, S Erkek, M Zapatka, K Kerl, I Buchhalter, V Hovestadt, ...
Cancer cell 29 (3), 379-393, 2016
1342016
Methylation of the TERT promoter and risk stratification of childhood brain tumours: an integrative genomic and molecular study
P Castelo-Branco, S Choufani, S Mack, D Gallagher, C Zhang, T Lipman, ...
The lancet oncology 14 (6), 534-542, 2013
1332013
IDH mutant diffuse and anaplastic astrocytomas have similar age at presentation and little difference in survival: a grading problem for WHO
DE Reuss, Y Mamatjan, D Schrimpf, D Capper, V Hovestadt, A Kratz, ...
Acta neuropathologica 129 (6), 867-873, 2015
1272015
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