| Driver mutations in histone H3. 3 and chromatin remodelling genes in paediatric glioblastoma J Schwartzentruber, A Korshunov, XY Liu, DTW Jones, E Pfaff, K Jacob, ... Nature 482 (7384), 226-231, 2012 | 1809 | 2012 |
| Hotspot Mutations in H3F3A and IDH1 Define Distinct Epigenetic and Biological Subgroups of Glioblastoma D Sturm, H Witt, V Hovestadt, DA Khuong-Quang, DTW Jones, ... Cancer Cell 22 (4), 425-437, 2012 | 1353 | 2012 |
| DNA methylation-based classification of central nervous system tumours D Capper, DTW Jones, M Sill, V Hovestadt, D Schrimpf, D Sturm, ... Nature 555 (7697), 469-474, 2018 | 746 | 2018 |
| Dissecting the genomic complexity underlying medulloblastoma DTW Jones, N Jäger, M Kool, T Zichner, B Hutter, M Sultan, YJ Cho, ... Nature 488 (7409), 100-105, 2012 | 741 | 2012 |
| Molecular Classification of Ependymal Tumors across All CNS Compartments, Histopathological Grades, and Age Groups KW Pajtler, H Witt, M Sill, DTW Jones, V Hovestadt, F Kratochwil, K Wani, ... Cancer Cell 27 (5), 728-743, 2015 | 594 | 2015 |
| Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma DTW Jones, B Hutter, N Jäger, A Korshunov, M Kool, HJ Warnatz, ... Nature genetics 45 (8), 927-932, 2013 | 587 | 2013 |
| Genome sequencing of SHH medulloblastoma predicts genotype-related response to smoothened inhibition M Kool, DTW Jones, N Jäger, PA Northcott, TJ Pugh, V Hovestadt, ... Cancer cell 25 (3), 393-405, 2014 | 527 | 2014 |
| Epigenomic alterations define lethal CIMP-positive ependymomas of infancy SC Mack, H Witt, RM Piro, L Gu, S Zuyderduyn, AM Stütz, X Wang, ... Nature 506 (7489), 445-450, 2014 | 469 | 2014 |
| Reduced H3K27me3 and DNA hypomethylation are major drivers of gene expression in K27M mutant pediatric high-grade gliomas S Bender, Y Tang, AM Lindroth, V Hovestadt, DTW Jones, M Kool, ... Cancer cell 24 (5), 660-672, 2013 | 454 | 2013 |
| New Brain Tumor Entities Emerge from Molecular Classification of CNS-PNETs D Sturm, BA Orr, UH Toprak, V Hovestadt, DTW Jones, D Capper, M Sill, ... Cell 164 (5), 1060-1072, 2016 | 448 | 2016 |
| The whole-genome landscape of medulloblastoma subtypes PA Northcott, I Buchhalter, AS Morrissy, V Hovestadt, J Weischenfeldt, ... Nature 547 (7663), 311-317, 2017 | 406 | 2017 |
| Enhancer hijacking activates GFI1 family oncogenes in medulloblastoma PA Northcott, C Lee, T Zichner, AM Stütz, S Erkek, D Kawauchi, DJH Shih, ... Nature 511 (7510), 428-434, 2014 | 396 | 2014 |
| Decoupling genetics, lineages, and microenvironment in IDH-mutant gliomas by single-cell RNA-seq AS Venteicher, I Tirosh, C Hebert, K Yizhak, C Neftel, MG Filbin, ... Science 355 (6332), 2017 | 380 | 2017 |
| MicroRNA sequence and expression analysis in breast tumors by deep sequencing TA Farazi, HM Horlings, J Jelle, A Mihailovic, H Halfwerk, P Morozov, ... Cancer research 71 (13), 4443-4453, 2011 | 371 | 2011 |
| ATRX and IDH1-R132H immunohistochemistry with subsequent copy number analysis and IDH sequencing as a basis for an “integrated” diagnostic approach for adult astrocytoma … DE Reuss, F Sahm, D Schrimpf, B Wiestler, D Capper, C Koelsche, ... Acta neuropathologica 129 (1), 133-146, 2015 | 367 | 2015 |
| Recurrent mutation of the ID3 gene in Burkitt lymphoma identified by integrated genome, exome and transcriptome sequencing. J Richter, M Schlesner, S Hoffmann, M Kreuz, E Leich, B Burkhardt, ... Nature genetics, 2012 | 348 | 2012 |
| Decoding the regulatory landscape of medulloblastoma using DNA methylation sequencing V Hovestadt, DTW Jones, S Picelli, W Wang, M Kool, PA Northcott, ... Nature 510 (7506), 537-541, 2014 | 301 | 2014 |
| DNA methylation-based classification and grading system for meningioma: a multicentre, retrospective analysis F Sahm, D Schrimpf, D Stichel, DTW Jones, T Hielscher, S Schefzyk, ... The Lancet Oncology 18 (5), 682-694, 2017 | 298 | 2017 |
| BCAT1 promotes cell proliferation through amino acid catabolism in gliomas carrying wild-type IDH1 M Tönjes, S Barbus, YJ Park, W Wang, M Schlotter, AM Lindroth, ... Nature medicine 19 (7), 901-908, 2013 | 283 | 2013 |
| Atypical Teratoid/Rhabdoid Tumors Are Comprised of Three Epigenetic Subgroups with Distinct Enhancer Landscapes PD Johann, S Erkek, M Zapatka, K Kerl, I Buchhalter, V Hovestadt, ... Cancer cell 29 (3), 379-393, 2016 | 277 | 2016 |
Stefan M. PfisterProfessor of Pediatrics, Hopp-Children´s Cancer Center Heidelberg (KiTZ)Verified email at kitz-heidelberg.de
