Sander M. Houten
Sander M. Houten
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Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation
M Watanabe, SM Houten, C Mataki, MA Christoffolete, BW Kim, H Sato, ...
Nature 439 (7075), 484-489, 2006
Bile acids lower triglyceride levels via a pathway involving FXR, SHP, and SREBP-1c
M Watanabe, SM Houten, L Wang, A Moschetta, DJ Mangelsdorf, ...
The Journal of clinical investigation 113 (10), 1408-1418, 2004
Specific SIRT1 activation mimics low energy levels and protects against diet-induced metabolic disorders by enhancing fat oxidation
JN Feige, M Lagouge, C Canto, A Strehle, SM Houten, JC Milne, ...
Cell metabolism 8 (5), 347-358, 2008
A general introduction to the biochemistry of mitochondrial fatty acid β-oxidation
SM Houten, RJA Wanders
Journal of inherited metabolic disease 33 (5), 469-477, 2010
Endocrine functions of bile acids
SM Houten, M Watanabe, J Auwerx
The EMBO journal 25 (7), 1419-1425, 2006
Serum bile acids are higher in humans with prior gastric bypass: potential contribution to improved glucose and lipid metabolism
ME Patti, SM Houten, AC Bianco, R Bernier, PR Larsen, JJ Holst, ...
Obesity 17 (9), 1671-1677, 2009
Mutations in MVK, encoding mevalonate kinase, cause hyperimmunoglobulinaemia D and periodic fever syndrome
SM Houten, W Kuis, M Duran, TJ De Koning, A van Royen-Kerkhof, ...
Nature genetics 22 (2), 175-177, 1999
Acylcarnitines: reflecting or inflicting insulin resistance?
MG Schooneman, FM Vaz, SM Houten, MR Soeters
Diabetes 62 (1), 1-8, 2013
The metabolic footprint of aging in mice
RH Houtkooper, C Argmann, SM Houten, C Cantó, EH Jeninga, ...
Scientific reports 1 (1), 1-11, 2011
PARP-2 regulates SIRT1 expression and whole-body energy expenditure
P Bai, C Canto, A Brunyánszki, A Huber, M Szántó, Y Cen, H Yamamoto, ...
Cell metabolism 13 (4), 450-460, 2011
Compensation by the muscle limits the metabolic consequences of lipodystrophy in PPARγ hypomorphic mice
H Koutnikova, TA Cock, M Watanabe, SM Houten, MF Champy, A Dierich, ...
Proceedings of the National Academy of Sciences 100 (24), 14457-14462, 2003
Lowering bile acid pool size with a synthetic farnesoid X receptor (FXR) agonist induces obesity and diabetes through reduced energy expenditure
M Watanabe, Y Horai, SM Houten, K Morimoto, T Sugizaki, E Arita, ...
Journal of Biological Chemistry 286 (30), 26913-26920, 2011
The biochemistry and physiology of mitochondrial fatty acid β-oxidation and its genetic disorders
SM Houten, S Violante, FV Ventura, RJA Wanders
Annual review of physiology 78, 23-44, 2016
Systems proteomics of liver mitochondria function
EG Williams, Y Wu, P Jha, S Dubuis, P Blattmann, CA Argmann, ...
Science 352 (6291), 2016
Multilayered genetic and omics dissection of mitochondrial activity in a mouse reference population
Y Wu, EG Williams, S Dubuis, A Mottis, V Jovaisaite, SM Houten, ...
Cell 158 (6), 1415-1430, 2014
Lack of isoprenoid products raises ex vivo interleukin‐1β secretion in hyperimmunoglobulinemia D and periodic fever syndrome
J Frenkel, GT Rijkers, SHL Mandey, SWM Buurman, SM Houten, ...
Arthritis & Rheumatism 46 (10), 2794-2803, 2002
The enzymology of mitochondrial fatty acid beta-oxidation and its application to follow-up analysis of positive neonatal screening results
RJA Wanders, JPN Ruiter, L IJlst, HR Waterham, SM Houten
Journal of inherited metabolic disease 33 (5), 479-494, 2010
Compromised intestinal lipid absorption in mice with a liver-specific deficiency of liver receptor homolog 1
C Mataki, BC Magnier, SM Houten, JS Annicotte, C Argmann, C Thomas, ...
Molecular and cellular biology 27 (23), 8330-8339, 2007
Acyl-CoA dehydrogenase 9 is required for the biogenesis of oxidative phosphorylation complex I
J Nouws, L Nijtmans, SM Houten, M van den Brand, M Huynen, ...
Cell metabolism 12 (3), 283-294, 2010
Peroxisome proliferator‐activated receptor‐γ: too much of a good thing causes harm
TA Cock, SM Houten, J Auwerx
EMBO reports 5 (2), 142-147, 2004
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