Clinical spectrum of obesity and mutations in the melanocortin 4 receptor gene IS Farooqi, JM Keogh, GSH Yeo, EJ Lank, T Cheetham, S O'Rahilly New England Journal of Medicine 348 (12), 1085-1095, 2003 | 2064 | 2003 |
The obesity-associated FTO gene encodes a 2-oxoglutarate-dependent nucleic acid demethylase T Gerken, CA Girard, YCL Tung, CJ Webby, V Saudek, KS Hewitson, ... Science 318 (5855), 1469-1472, 2007 | 1835 | 2007 |
A frameshift mutation in MC4R associated with dominantly inherited human obesity GSH Yeo, IS Farooqi, S Aminian, DJ Halsall, RG Stanhope, S O'Rahilly Nature genetics 20 (2), 111-112, 1998 | 1412 | 1998 |
Dominant and recessive inheritance of morbid obesity associated with melanocortin 4 receptor deficiency IS Farooqi, GSH Yeo, JM Keogh, S Aminian, SA Jebb, G Butler, ... The Journal of clinical investigation 106 (2), 271-279, 2000 | 1017 | 2000 |
The genetics of obesity: from discovery to biology RJF Loos, GSH Yeo Nature Reviews Genetics 23 (2), 120-133, 2022 | 804 | 2022 |
The bigger picture of FTO—the first GWAS-identified obesity gene RJF Loos, GSH Yeo Nature Reviews Endocrinology 10 (1), 51-61, 2014 | 760 | 2014 |
A de novo mutation affecting human TrkB associated with severe obesity and developmental delay GSH Yeo, CC Connie Hung, J Rochford, J Keogh, J Gray, ... Nature neuroscience 7 (11), 1187-1189, 2004 | 680 | 2004 |
Hyperphagia, severe obesity, impaired cognitive function, and hyperactivity associated with functional loss of one copy of the brain-derived neurotrophic factor (BDNF) gene J Gray, GSH Yeo, JJ Cox, J Morton, ALR Adlam, JM Keogh, JA Yanovski, ... Diabetes 55 (12), 3366-3371, 2006 | 601 | 2006 |
Somatic mutations in ATP1A1 and CACNA1D underlie a common subtype of adrenal hypertension EAB Azizan, H Poulsen, P Tuluc, J Zhou, MV Clausen, A Lieb, C Maniero, ... Nature genetics 45 (9), 1055-1060, 2013 | 543 | 2013 |
PPAR gamma 2 prevents lipotoxicity by controlling adipose tissue expandability and peripheral lipid metabolism G Medina-Gomez, SL Gray, L Yetukuri, K Shimomura, S Virtue, ... PLoS genetics 3 (4), e64, 2007 | 490 | 2007 |
GDF15 mediates the effects of metformin on body weight and energy balance AP Coll, M Chen, P Taskar, D Rimmington, S Patel, JA Tadross, I Cimino, ... Nature 578 (7795), 444-448, 2020 | 465 | 2020 |
Loss-of-function mutation in the dioxygenase-encoding FTO gene causes severe growth retardation and multiple malformations S Boissel, O Reish, K Proulx, H Kawagoe-Takaki, B Sedgwick, GSH Yeo, ... The American Journal of Human Genetics 85 (1), 106-111, 2009 | 455 | 2009 |
The relationship between glial cell mechanosensitivity and foreign body reactions in the central nervous system P Moshayedi, G Ng, JCF Kwok, GSH Yeo, CE Bryant, JW Fawcett, ... Biomaterials 35 (13), 3919-3925, 2014 | 416 | 2014 |
Overlap of endocrine hormone expression in the mouse intestine revealed by transcriptional profiling and flow cytometry AM Habib, P Richards, LS Cairns, GJ Rogers, CAM Bannon, HE Parker, ... Endocrinology 153 (7), 3054-3065, 2012 | 411 | 2012 |
Transcriptome analysis of embryonic and adult sensory axons reveals changes in mRNA repertoire localization LF Gumy, GSH Yeo, YCL Tung, KH Zivraj, D Willis, G Coppola, BYH Lam, ... Rna 17 (1), 85-98, 2011 | 400 | 2011 |
Unraveling the brain regulation of appetite: lessons from genetics GSH Yeo, LK Heisler Nature neuroscience 15 (10), 1343-1349, 2012 | 370 | 2012 |
Subcellular profiling reveals distinct and developmentally regulated repertoire of growth cone mRNAs KH Zivraj, YCL Tung, M Piper, L Gumy, JW Fawcett, GSH Yeo, CE Holt Journal of Neuroscience 30 (46), 15464-15478, 2010 | 364 | 2010 |
A missense mutation disrupting a dibasic prohormone processing site in pro-opiomelanocortin (POMC) increases susceptibility to early-onset obesity through a novel molecular … BG Challis, LE Pritchard, JWM Creemers, J Delplanque, JM Keogh, ... Human molecular genetics 11 (17), 1997-2004, 2002 | 360 | 2002 |
Serotonin activates the hypothalamic–pituitary–adrenal axis via serotonin 2C receptor stimulation LK Heisler, N Pronchuk, K Nonogaki, L Zhou, J Raber, L Tung, GSH Yeo, ... Journal of Neuroscience 27 (26), 6956-6964, 2007 | 350 | 2007 |
Serotonin 5-HT2C Receptor Agonist Promotes Hypophagia via Downstream Activation of Melanocortin 4 Receptors DD Lam, MJ Przydzial, SH Ridley, GSH Yeo, JJ Rochford, S O’Rahilly, ... Endocrinology 149 (3), 1323-1328, 2008 | 331 | 2008 |