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Philipp le Coutre
Philipp le Coutre
Professor für Innere Medizin, Charité, Humboldt University, Berlin
Bestätigte E-Mail-Adresse bei charite.de
Titel
Zitiert von
Zitiert von
Jahr
Nilotinib versus imatinib for newly diagnosed chronic myeloid leukemia
G Saglio, DW Kim, S Issaragrisil, P Le Coutre, G Etienne, C Lobo, ...
New England Journal of Medicine 362 (24), 2251-2259, 2010
20942010
A phase 2 trial of ponatinib in Philadelphia chromosome–positive leukemias
JE Cortes, DW Kim, J Pinilla-Ibarz, P Le Coutre, R Paquette, C Chuah, ...
New England Journal of Medicine 369 (19), 1783-1796, 2013
12302013
Nilotinib (formerly AMN107), a highly selective BCR-ABL tyrosine kinase inhibitor, is effective in patients with Philadelphia chromosome–positive chronic myelogenous leukemia …
HM Kantarjian, F Giles, N Gattermann, K Bhalla, G Alimena, F Palandri, ...
Blood, The Journal of the American Society of Hematology 110 (10), 3540-3546, 2007
9612007
Long-term benefits and risks of frontline nilotinib vs imatinib for chronic myeloid leukemia in chronic phase: 5-year update of the randomized ENESTnd trial
A Hochhaus, G Saglio, TP Hughes, RA Larson, DW Kim, S Issaragrisil, ...
Leukemia 30 (5), 1044-1054, 2016
8742016
Induction of resistance to the Abelson inhibitor STI571 in human leukemic cells through gene amplification
P le Coutre, E Tassi, M Varella-Garcia, R Barni, L Mologni, G Cabrita, ...
Blood, The Journal of the American Society of Hematology 95 (5), 1758-1766, 2000
7032000
Multicenter independent assessment of outcomes in chronic myeloid leukemia patients treated with imatinib
C Gambacorti-Passerini, L Antolini, FX Mahon, F Guilhot, M Deininger, ...
Journal of the National Cancer Institute 103 (7), 553-561, 2011
5182011
Ponatinib efficacy and safety in Philadelphia chromosome–positive leukemia: final 5-year results of the phase 2 PACE trial
JE Cortes, DW Kim, J Pinilla-Ibarz, PD le Coutre, R Paquette, C Chuah, ...
Blood, The Journal of the American Society of Hematology 132 (4), 393-404, 2018
5122018
Nilotinib is effective in patients with chronic myeloid leukemia in chronic phase after imatinib resistance or intolerance: 24-month follow-up results
HM Kantarjian, FJ Giles, KN Bhalla, J Pinilla-Ibarz, RA Larson, ...
Blood, The Journal of the American Society of Hematology 117 (4), 1141-1145, 2011
5062011
European LeukemiaNet recommendations for the management and avoidance of adverse events of treatment in chronic myeloid leukaemia
JL Steegmann, M Baccarani, M Breccia, LF Casado, V García-Gutiérrez, ...
Leukemia 30 (8), 1648-1671, 2016
4932016
In Vivo Eradication of Human BCR/ABL-Positive Leukemia Cells With an ABL Kinase Inhibitor
P Le Coutre, L Mologni, L Cleris, E Marchesi, E Buchdunger, R Giardini, ...
Journal of the National Cancer Institute 91 (2), 163-168, 1999
4911999
Role of α1 Acid Glycoprotein in the In Vivo Resistance of Human BCR-ABL+ Leukemic Cells to the Abl Inhibitor STI571
C Gambacorti-Passerini, R Barni, P le Coutre, M Zucchetti, G Cabrita, ...
Journal of the National Cancer Institute 92 (20), 1641-1650, 2000
4902000
Bosutinib versus imatinib for newly diagnosed chronic myeloid leukemia: results from the randomized BFORE trial
JE Cortes, C Gambacorti-Passerini, MW Deininger, MJ Mauro, C Chuah, ...
Journal of Clinical Oncology 36 (3), 231, 2018
4812018
Inhibition of the ABL kinase activity blocks the proliferation of BCR/ABL+ leukemic cells and induces apoptosis
C Gambacorti-Passerini, P Le Coutre, L Mologni, M Fanelli, C Bertazzoli, ...
Blood Cells, Molecules, and Diseases 23 (3), 380-394, 1997
4581997
Nilotinib (formerly AMN107), a highly selective BCR-ABL tyrosine kinase inhibitor, is active in patients with imatinib-resistant or-intolerant accelerated-phase chronic …
P Le Coutre, OG Ottmann, F Giles, DW Kim, J Cortes, N Gattermann, ...
Blood, The Journal of the American Society of Hematology 111 (4), 1834-1839, 2008
3822008
Asciminib in chronic myeloid leukemia after ABL kinase inhibitor failure
TP Hughes, MJ Mauro, JE Cortes, H Minami, D Rea, DJ DeAngelo, ...
New England Journal of Medicine 381 (24), 2315-2326, 2019
3482019
Treatment-free remission following frontline nilotinib in patients with chronic myeloid leukemia in chronic phase: results from the ENESTfreedom study
A Hochhaus, T Masszi, FJ Giles, JP Radich, DM Ross, ...
Leukemia 31 (7), 1525-1531, 2017
3062017
Vascular safety issues in CML patients treated with BCR/ABL1 kinase inhibitors
P Valent, E Hadzijusufovic, GH Schernthaner, D Wolf, D Rea, P le Coutre
Blood, The Journal of the American Society of Hematology 125 (6), 901-906, 2015
3012015
Nilotinib in imatinib-resistant or imatinib-intolerant patients with chronic myeloid leukemia in chronic phase: 48-month follow-up results of a phase II study
FJ Giles, PD Le Coutre, J Pinilla-Ibarz, RA Larson, N Gattermann, ...
Leukemia 27 (1), 107-112, 2013
2912013
Peripheral artery occlusive disease in chronic phase chronic myeloid leukemia patients treated with nilotinib or imatinib
TD Kim, D Rea, M Schwarz, P Grille, FE Nicolini, G Rosti, L Levato, ...
Leukemia 27 (6), 1316-1321, 2013
2842013
Ponatinib versus imatinib for newly diagnosed chronic myeloid leukaemia: an international, randomised, open-label, phase 3 trial
JH Lipton, C Chuah, A Guerci-Bresler, G Rosti, D Simpson, S Assouline, ...
The Lancet Oncology 17 (5), 612-621, 2016
2642016
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