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Iliya Lefterov
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Binding of the positron emission tomography tracer Pittsburgh compound-B reflects the amount of amyloid-β in Alzheimer's disease brain but not in transgenic mouse brain
WE Klunk, BJ Lopresti, MD Ikonomovic, IM Lefterov, RP Koldamova, ...
Journal of Neuroscience 25 (46), 10598-10606, 2005
4572005
Lack of ABCA1 considerably decreases brain ApoE level and increases amyloid deposition in APP23 mice
R Koldamova, M Staufenbiel, I Lefterov
Journal of Biological Chemistry 280 (52), 43224-43235, 2005
4142005
The liver X receptor ligand T0901317 decreases amyloid β production in vitro and in a mouse model of Alzheimer's disease
RP Koldamova, IM Lefterov, M Staufenbiel, D Wolfe, S Huang, ...
Journal of Biological Chemistry 280 (6), 4079-4088, 2005
3222005
22R-hydroxycholesterol and 9-cis-retinoic acid induce ATP-binding cassette transporter A1 expression and cholesterol efflux in brain cells and decrease amyloid β secretion
RP Koldamova, IM Lefterov, MD Ikonomovic, J Skoko, PI Lefterov, ...
Journal of Biological Chemistry 278 (15), 13244-13256, 2003
2942003
Liver X receptor agonist treatment ameliorates amyloid pathology and memory deficits caused by high-fat diet in APP23 mice
NF Fitz, A Cronican, T Pham, A Fogg, AH Fauq, R Chapman, I Lefterov, ...
Journal of Neuroscience 30 (20), 6862-6872, 2010
1992010
The role of APOE and TREM2 in Alzheimer′ s disease—current understanding and perspectives
CM Wolfe, NF Fitz, KN Nam, I Lefterov, R Koldamova
International journal of molecular sciences 20 (1), 81, 2018
1622018
Apolipoprotein AI directly interacts with amyloid precursor protein and inhibits Aβ aggregation and toxicity
RP Koldamova, IM Lefterov, MI Lefterova, JS Lazo
Biochemistry 40 (12), 3553-3560, 2001
1562001
Abca1 deficiency affects Alzheimer's disease-like phenotype in human ApoE4 but not in ApoE3-targeted replacement mice
NF Fitz, AA Cronican, M Saleem, AH Fauq, R Chapman, I Lefterov, ...
Journal of Neuroscience 32 (38), 13125-13136, 2012
1492012
ATP-binding cassette transporter A1: from metabolism to neurodegeneration
R Koldamova, NF Fitz, I Lefterov
Neurobiology of disease 72, 13-21, 2014
1402014
Apolipoprotein AI deficiency increases cerebral amyloid angiopathy and cognitive deficits in APP/PS1ΔE9 mice
I Lefterov, NF Fitz, AA Cronican, A Fogg, P Lefterov, R Kodali, R Wetzel, ...
Journal of Biological Chemistry 285 (47), 36945-36957, 2010
1362010
The role of ATP-binding cassette transporter A1 in Alzheimer's disease and neurodegeneration
R Koldamova, NF Fitz, I Lefterov
Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2010
1122010
Heavy chronic intermittent ethanol exposure alters small noncoding RNAs in mouse sperm and epididymosomes
GR Rompala, A Mounier, CM Wolfe, Q Lin, GE Homanics
Frontiers in genetics 9, 323949, 2018
1072018
Expression profiling in APP23 mouse brain: inhibition of Aβ amyloidosis and inflammation in response to LXR agonist treatment
I Lefterov, A Bookout, Z Wang, M Staufenbiel, D Mangelsdorf, ...
Molecular neurodegeneration 2, 1-15, 2007
1042007
Genome-wide alteration of histone H3K9 acetylation pattern in mouse offspring prenatally exposed to arsenic
AA Cronican, NF Fitz, A Carter, M Saleem, S Shiva, A Barchowsky, ...
PloS one 8 (2), e53478, 2013
1002013
Effect of high fat diet on phenotype, brain transcriptome and lipidome in Alzheimer’s model mice
KN Nam, A Mounier, CM Wolfe, NF Fitz, AY Carter, EL Castranio, ...
Scientific reports 7 (1), 4307, 2017
842017
Genome-wide approaches reveal EGR1-controlled regulatory networks associated with neurodegeneration
R Koldamova, J Schug, M Lefterova, AA Cronican, NF Fitz, FA Davenport, ...
Neurobiology of disease 63, 107-114, 2014
802014
Role of LXR and ABCA1 in the pathogenesis of Alzheimer's disease-implications for a new therapeutic approach
R Koldamova, I Lefterov
Current Alzheimer research 4 (2), 171-178, 2007
722007
Memory Deficits in APP23/Abca1+/− Mice Correlate with the Level of Aβ Oligomers
I Lefterov, NF Fitz, A Cronican, P Lefterov, M Staufenbiel, R Koldamova
ASN neuro 1 (2), AN20090015, 2009
712009
Phospholipids of APOE lipoproteins activate microglia in an isoform-specific manner in preclinical models of Alzheimer’s disease
NF Fitz, KN Nam, CM Wolfe, F Letronne, BE Playso, BE Iordanova, ...
Nature communications 12 (1), 3416, 2021
702021
Bexarotene-activated retinoid X receptors regulate neuronal differentiation and dendritic complexity
A Mounier, D Georgiev, KN Nam, NF Fitz, EL Castranio, CM Wolfe, ...
Journal of Neuroscience 35 (34), 11862-11876, 2015
692015
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