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Hiroshi Kimura
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Year
Organ/body-on-a-chip based on microfluidic technology for drug discovery
H Kimura, Y Sakai, T Fujii
Drug metabolism and pharmacokinetics 33 (1), 43-48, 2018
4282018
An integrated microfluidic system for long-term perfusion culture and on-line monitoring of intestinal tissue models
H Kimura, T Yamamoto, H Sakai, Y Sakai, T Fujii
Lab on a Chip 8 (5), 741-746, 2008
3342008
Bile canaliculi formation by aligning rat primary hepatocytes in a microfluidic device
Y Nakao, H Kimura, Y Sakai, T Fujii
Biomicrofluidics 5 (2), 2011
1992011
Long-term ex vivo maintenance of testis tissues producing fertile sperm in a microfluidic device
M Komeya, H Kimura, H Nakamura, T Yokonishi, T Sato, K Kojima, ...
Scientific reports 6 (1), 21472, 2016
1842016
An on-chip small intestine–liver model for pharmacokinetic studies
H Kimura, T Ikeda, H Nakayama, Y Sakai, T Fujii
Journal of laboratory automation 20 (3), 265-273, 2015
1272015
Pumpless microfluidic system driven by hydrostatic pressure induces and maintains mouse spermatogenesis in vitro
M Komeya, K Hayashi, H Nakamura, H Yamanaka, H Sanjo, K Kojima, ...
Scientific reports 7 (1), 15459, 2017
1052017
ZnO-based microfluidic pH sensor: a versatile approach for quick recognition of circulating tumor cells in blood
GK Mani, M Morohoshi, Y Yasoda, S Yokoyama, H Kimura, K Tsuchiya
ACS applied materials & interfaces 9 (6), 5193-5203, 2017
732017
Spatiotemporally controlled delivery of soluble factors for stem cell differentiation
J Kawada, H Kimura, H Akutsu, Y Sakai, T Fujii
Lab on a Chip 12 (21), 4508-4515, 2012
582012
Combination of microwell structures and direct oxygenation enables efficient and size‐regulated aggregate formation of an insulin‐secreting pancreatic β‐cell line
M Shinohara, H Kimura, K Montagne, K Komori, T Fujii, Y Sakai
Biotechnology progress 30 (1), 178-187, 2014
552014
A monolayer microfluidic device supporting mouse spermatogenesis with improved visibility
H Yamanaka, M Komeya, H Nakamura, H Sanjo, T Sato, M Yao, H Kimura, ...
Biochemical and Biophysical Research Communications 500 (4), 885-891, 2018
502018
Neonatal testis growth recreated in vitro by two‐dimensional organ spreading
K Kojima, H Nakamura, M Komeya, H Yamanaka, Y Makino, Y Okada, ...
Biotechnology and bioengineering 115 (12), 3030-3041, 2018
372018
Identification of a novel alpha‐fetoprotein‐expressing cell population induced by the Jagged1/Notch2 signal in murine fibrotic liver
Y Nakano, S Nakao, H Sumiyoshi, K Mikami, Y Tanno, M Sueoka, ...
Hepatology communications 1 (3), 215-229, 2017
372017
A pharmacokinetic–pharmacodynamic model based on multi-organ-on-a-chip for drug–drug interaction studies
K Shinha, W Nihei, T Ono, R Nakazato, H Kimura
Biomicrofluidics 14 (4), 2020
352020
On-chip single embryo coculture with microporous-membrane-supported endometrial cells
H Kimura, H Nakamura, T Akai, T Yamamoto, H Hattori, Y Sakai, T Fujii
IEEE Transactions on NanoBioscience 8 (4), 318-324, 2009
322009
In vitro spermatogenesis in two‐dimensionally spread mouse testis tissues
M Komeya, H Yamanaka, H Sanjo, M Yao, H Nakamura, H Kimura, T Fujii, ...
Reproductive medicine and biology 18 (4), 362-369, 2019
272019
Rat in vitro spermatogenesis promoted by chemical supplementations and oxygen-tension control
T Matsumura, T Sato, T Abe, H Sanjo, K Katagiri, H Kimura, T Fujii, ...
Scientific Reports 11 (1), 3458, 2021
252021
Applications of nanosheets in frontier cellular research
W Huang, Y Sunami, H Kimura, S Zhang
Nanomaterials 8 (7), 519, 2018
222018
Coculture with hiPS-derived intestinal cells enhanced human hepatocyte functions in a pneumatic-pressure-driven two-organ microphysiological system
M Shinohara, H Arakawa, Y Oda, N Shiraki, S Sugiura, T Nishiuchi, ...
Scientific reports 11 (1), 5437, 2021
202021
A kinetic pump integrated microfluidic plate (Kim-plate) with high usability for cell culture-based multiorgan microphysiological systems
K Shinha, W Nihei, H Nakamura, T Goto, T Kawanishi, N Ishida, ...
Micromachines 12 (9), 1007, 2021
192021
Image-based evaluations of distribution and cytotoxicity of Irinotecan (CPT-11) in a multi-compartment micro-cell coculture device
H Nakayama, H Kimura, T Fujii, Y Sakai
Journal of bioscience and bioengineering 117 (6), 756-762, 2014
152014
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Articles 1–20