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Zander Bühler-Harteveld
Zander Bühler-Harteveld
Scientist, Generate Biomedicines
Verified email at generatebiomedicines.com
Title
Cited by
Cited by
Year
Engineered anti-CRISPR proteins for optogenetic control of CRISPR–Cas9
F Bubeck, MD Hoffmann, Z Harteveld, S Aschenbrenner, A Bietz, ...
Nature methods 15 (11), 924-927, 2018
1962018
De novo design of protein interactions with learned surface fingerprints
P Gainza, S Wehrle, A Van Hall-Beauvais, A Marchand, A Scheck, ...
Nature 617 (7959), 176-184, 2023
732023
Optogenetic control of Neisseria meningitidis Cas9 genome editing using an engineered, light-switchable anti-CRISPR protein
MD Hoffmann, J Mathony, J Upmeier zu Belzen, Z Harteveld, ...
Nucleic acids research 49 (5), e29-e29, 2021
322021
Computational design of anti-CRISPR proteins with improved inhibition potency
J Mathony, Z Harteveld, C Schmelas, J Upmeier zu Belzen, ...
Nature chemical biology 16 (7), 725-730, 2020
212020
Whole-genome doubling drives oncogenic loss of chromatin segregation
RA Lambuta, L Nanni, Y Liu, J Diaz-Miyar, A Iyer, D Tavernari, ...
Nature 615 (7954), 925-933, 2023
182023
rstoolbox-a Python library for large-scale analysis of computational protein design data and structural bioinformatics
J Bonet, Z Harteveld, F Sesterhenn, A Scheck, BE Correia
BMC bioinformatics 20, 1-13, 2019
132019
A generic framework for hierarchical de novo protein design
Z Harteveld, J Bonet, S Rosset, C Yang, F Sesterhenn, BE Correia
Proceedings of the National Academy of Sciences 119 (43), e2206111119, 2022
102022
De novo design of site-specific protein interactions with learned surface fingerprints
P Gainza, S Wehrle, A Van Hall-Beauvais, A Marchand, A Scheck, ...
bioRxiv, 2022.06. 16.496402, 2022
62022
Deep sharpening of topological features for de novo protein design
Z Harteveld, J Southern, M Defferrard, A Loukas, P Vandergheynst, ...
ICLR2022 Machine Learning for Drug Discovery, 2022
62022
A Rosetta-based protein design protocol converging to natural sequences
G Sormani, Z Harteveld, S Rosset, B Correia, A Laio
The Journal of Chemical Physics 154 (7), 2021
62021
Exploring" dark matter" protein folds using deep learning
Z Harteveld, A Van Hall-Beauvais, I Morozova, J Southern, CA Goverde, ...
bioRxiv, 2023.08. 30.555621, 2023
32023
rstoolbox: management and analysis of computationally designed structural ensembles
J Bonet, Z Harteveld, F Sesterhenn, A Scheck, BE Correia
bioRxiv, 428045, 2018
12018
Systems and methods for de novo design of protein interactions with learned surface fingerprints
PG Cirauqui, S Wehrle, A Van Hall-Beauvais, A Marchand, A Scheck, ...
US Patent App. 18/206,873, 2023
2023
Machine Learning in Protein Science De Novo Design of Site-Specific Protein Binders Using Surface Fingerprints
V Hall-Beauvais, P Gainza, S Wehrle, A Scheck, A Marchand, Z Harteveld, ...
Protein Science 32, 2023
2023
De novo design of site-specific protein interactions with learned surface fingerprints (preprint)
P Gainza, S Wehrle, A Van Hall-Beauvais, A Marchand, A Scheck, ...
2022
Towards automating de novo protein design for novel functionalities: controlling protein folds and protein-protein interactions
Z Harteveld
EPFL, 2022
2022
De Novo Design of Site-specific Protein Binders Using Surface Fingerprints
S Wehrle, V Hall-Beauvais, P Gainza, Z Harteveld, A Scheck, F Sverrisson, ...
Protein Science 30, 162-163, 2021
2021
Engineered Anti-CRISPR Proteins for Precision Control of CRISPR-Cas9
F Bubeck, MD Hoffmann, Z Harteveld, S Aschenbrenner, A Bietz, ...
Molecular Therapy 27 (4), 297-297, 2019
2019
LPDI
J Bonet Martinez, SM Buckley, KM Castro Gilabert, RM Chassot, ...
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