|Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors|
TC Chou, P Talalay
Advances in enzyme regulation 22, 27-55, 1984
|Theoretical basis, experimental design, and computerized simulation of synergism and antagonism in drug-combination studies (vol 58, pg 621-681, 2006)|
Pharmacological Reviews 58, 621-681, 2006
|Drug combination studies and their synergy quantification using the Chou-Talalay method|
Cancer research 70 (2), 440-446, 2010
|Human neutralizing monoclonal antibodies of the IgG1 subtype protect against mucosal simian–human immunodeficiency virus infection|
TW Baba, V Liska, R Hofmann-Lehmann, J Vlasak, W Xu, S Ayehunie, ...
Nature medicine 6 (2), 200, 2000
|Computerized quantitation of synergism and antagonism of taxol, topotecan, and cisplatin against human teratocarcinoma cell growth: a rational approach to clinical protocol design|
TC Chou, RJ Motzer, Y Tong, GJ Bosl
JNCI: Journal of the National Cancer Institute 86 (20), 1517-1524, 1994
|Analysis of combined drug effects: a new look at a very old problem|
TC Chou, P Talalay
Trends in Pharmacological Sciences 4, 450-454, 1983
|Synergism and antagonism in chemotherapy: The median-effect principle and the combination index for quantitation of synergism and antagonism|
Academic Press, San Diego, 1991
|Generalized equations for the analysis of inhibitions of Michaelis‐Menten and higher‐order kinetic systems with two or more mutually exclusive and nonexclusive inhibitors|
TC CHOU, P Talalay
European Journal of Biochemistry 115 (1), 207-216, 1981
|The median-effect principle and the combination index for quantitation of synergism and antagonism|
Synergism and antagonism in chemotherapy, 61-102, 1991
|Irinotecan is an active agent in untreated patients with metastatic colorectal cancer.|
JA Conti, NE Kemeny, LB Saltz, Y Huang, WP Tong, TC Chou, M Sun, ...
Journal of clinical oncology 14 (3), 709-715, 1996
|Derivation and properties of Michaelis-Menten type and Hill type equations for reference ligands|
Journal of theoretical biology 59 (2), 253-276, 1976
|Ribavirin antagonizes the effect of azidothymidine on HIV replication|
MW Vogt, KL Hartshorn, PA Furman, TC Chou, JA Fyfe, LA Coleman, ...
Science 235 (4794), 1376-1379, 1987
|Synergistic inhibition of human immunodeficiency virus in vitro by azidothymidine and recombinant alpha A interferon.|
KL Hartshorn, MW Vogt, TC Chou, RS Blumberg, R Byington, ...
Antimicrobial agents and chemotherapy 31 (2), 168-172, 1987
|Remote effects in macrolide formation through ring-forming olefin metathesis: an application to the synthesis of fully active epothilone congeners|
D Meng, DS Su, A Balog, P Bertinato, EJ Sorensen, SJ Danishefsky, ...
Journal of the American Chemical Society 119 (11), 2733-2734, 1997
|A simple generalized equation for the analysis of multiple inhibitions of Michaelis-Menten kinetic systems.|
TC Chou, P Talaly
Journal of Biological Chemistry 252 (18), 6438-6442, 1977
|Dose-effect analysis with microcomputers|
JH Chou, TC Chou
Biosoft, Cambridge. UK, pp. 1-93, 1987
|Dose-effect Analysis with Microcomputers: Quantitation of ED50, LD50, Synergism, Antagonism, Low-dose Risk, Receptor-ligand Binding and Enzyme Kinetics|
J Chou, TC Chou
Computer Software. Elsevier-Biosoft, Cambridge UK, 1985
|Quantitation of chemopreventive synergism between (-)-epigallocatechin-3-gallate and curcumin in normal, premalignant and malignant human oral epithelial cells.|
A Khafif, SP Schantz, TC Chou, D Edelstein, PG Sacks
Carcinogenesis 19 (3), 419-424, 1998
|Desoxyepothilone B: an efficacious microtubule-targeted antitumor agent with a promising in vivo profile relative to epothilone B|
TC Chou, XG Zhang, A Balog, DS Su, D Meng, K Savin, JR Bertino, ...
Proceedings of the National Academy of Sciences 95 (16), 9642-9647, 1998
|Pharmacokinetic interactions augment toxicities of sirolimus/cyclosporine combinations|
H Podder, SM Stepkowski, KL Napoli, J Clark, RR Verani, T Chou, ...
Journal of the American Society of Nephrology 12 (5), 1059-1071, 2001