Ting-Chao Chou
TitleCited byYear
Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors
TC Chou, P Talalay
Advances in enzyme regulation 22, 27-55, 1984
Theoretical basis, experimental design, and computerized simulation of synergism and antagonism in drug-combination studies (vol 58, pg 621-681, 2006)
TC Chou
Pharmacological Reviews 58, 621-681, 2006
Drug combination studies and their synergy quantification using the Chou-Talalay method
TC Chou
Cancer research 70 (2), 440-446, 2010
Human neutralizing monoclonal antibodies of the IgG1 subtype protect against mucosal simian–human immunodeficiency virus infection
TW Baba, V Liska, R Hofmann-Lehmann, J Vlasak, W Xu, S Ayehunie, ...
Nature medicine 6 (2), 200, 2000
Computerized quantitation of synergism and antagonism of taxol, topotecan, and cisplatin against human teratocarcinoma cell growth: a rational approach to clinical protocol design
TC Chou, RJ Motzer, Y Tong, GJ Bosl
JNCI: Journal of the National Cancer Institute 86 (20), 1517-1524, 1994
Analysis of combined drug effects: a new look at a very old problem
TC Chou, P Talalay
Trends in Pharmacological Sciences 4, 450-454, 1983
Synergism and antagonism in chemotherapy: The median-effect principle and the combination index for quantitation of synergism and antagonism
TC Chou
Academic Press, San Diego, 1991
Generalized equations for the analysis of inhibitions of Michaelis‐Menten and higher‐order kinetic systems with two or more mutually exclusive and nonexclusive inhibitors
TC CHOU, P Talalay
European Journal of Biochemistry 115 (1), 207-216, 1981
The median-effect principle and the combination index for quantitation of synergism and antagonism
TC Chou
Synergism and antagonism in chemotherapy, 61-102, 1991
Irinotecan is an active agent in untreated patients with metastatic colorectal cancer.
JA Conti, NE Kemeny, LB Saltz, Y Huang, WP Tong, TC Chou, M Sun, ...
Journal of clinical oncology 14 (3), 709-715, 1996
Derivation and properties of Michaelis-Menten type and Hill type equations for reference ligands
TC Chou
Journal of theoretical biology 59 (2), 253-276, 1976
Ribavirin antagonizes the effect of azidothymidine on HIV replication
MW Vogt, KL Hartshorn, PA Furman, TC Chou, JA Fyfe, LA Coleman, ...
Science 235 (4794), 1376-1379, 1987
Synergistic inhibition of human immunodeficiency virus in vitro by azidothymidine and recombinant alpha A interferon.
KL Hartshorn, MW Vogt, TC Chou, RS Blumberg, R Byington, ...
Antimicrobial agents and chemotherapy 31 (2), 168-172, 1987
Remote effects in macrolide formation through ring-forming olefin metathesis: an application to the synthesis of fully active epothilone congeners
D Meng, DS Su, A Balog, P Bertinato, EJ Sorensen, SJ Danishefsky, ...
Journal of the American Chemical Society 119 (11), 2733-2734, 1997
A simple generalized equation for the analysis of multiple inhibitions of Michaelis-Menten kinetic systems.
TC Chou, P Talaly
Journal of Biological Chemistry 252 (18), 6438-6442, 1977
Dose-effect analysis with microcomputers
JH Chou, TC Chou
Biosoft, Cambridge. UK, pp. 1-93, 1987
Dose-effect Analysis with Microcomputers: Quantitation of ED50, LD50, Synergism, Antagonism, Low-dose Risk, Receptor-ligand Binding and Enzyme Kinetics
J Chou, TC Chou
Computer Software. Elsevier-Biosoft, Cambridge UK, 1985
Quantitation of chemopreventive synergism between (-)-epigallocatechin-3-gallate and curcumin in normal, premalignant and malignant human oral epithelial cells.
A Khafif, SP Schantz, TC Chou, D Edelstein, PG Sacks
Carcinogenesis 19 (3), 419-424, 1998
Desoxyepothilone B: an efficacious microtubule-targeted antitumor agent with a promising in vivo profile relative to epothilone B
TC Chou, XG Zhang, A Balog, DS Su, D Meng, K Savin, JR Bertino, ...
Proceedings of the National Academy of Sciences 95 (16), 9642-9647, 1998
Pharmacokinetic interactions augment toxicities of sirolimus/cyclosporine combinations
H Podder, SM Stepkowski, KL Napoli, J Clark, RR Verani, T Chou, ...
Journal of the American Society of Nephrology 12 (5), 1059-1071, 2001
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Articles 1–20