Derivation of human midbrain-specific organoids from neuroepithelial stem cells AS Monzel, LM Smits, K Hemmer, S Hachi, EL Moreno, T van Wuellen, ... Stem cell reports 8 (5), 1144-1154, 2017 | 415 | 2017 |
Single-cell sequencing of human midbrain reveals glial activation and a Parkinson-specific neuronal state S Smajić, CA Prada-Medina, Z Landoulsi, J Ghelfi, S Delcambre, ... Brain 145 (3), 964-978, 2022 | 285 | 2022 |
3D cultures of Parkinson's disease‐specific dopaminergic neurons for high content phenotyping and drug testing S Bolognin, M Fossépré, X Qing, J Jarazo, J Ščančar, EL Moreno, ... Advanced Science 6 (1), 1800927, 2019 | 129 | 2019 |
FACS-assisted CRISPR-Cas9 genome editing facilitates Parkinson's disease modeling J Arias-Fuenzalida, J Jarazo, X Qing, J Walter, G Gomez-Giro, SL Nickels, ... Stem Cell Reports 9 (5), 1423-1431, 2017 | 111 | 2017 |
Neural stem cells of Parkinson's disease patients exhibit aberrant mitochondrial morphology and functionality J Walter, S Bolognin, PMA Antony, SL Nickels, SK Poovathingal, ... Stem cell reports 12 (5), 878-889, 2019 | 98 | 2019 |
Microglia integration into human midbrain organoids leads to increased neuronal maturation and functionality S Sabate‐Soler, SL Nickels, C Saraiva, E Berger, U Dubonyte, K Barmpa, ... Glia 70 (7), 1267-1288, 2022 | 97 | 2022 |
Automated microfluidic cell culture of stem cell derived dopaminergic neurons KIW Kane, EL Moreno, S Hachi, M Walter, J Jarazo, MAP Oliveira, ... Scientific reports 9 (1), 1796, 2019 | 95 | 2019 |
CRISPR/Cas9 and piggyBac-mediated footprint-free LRRK2-G2019S knock-in reveals neuronal complexity phenotypes and α-Synuclein modulation in dopaminergic neurons X Qing, J Walter, J Jarazo, J Arias-Fuenzalida, AL Hillje, JC Schwamborn Stem Cell Research 24, 44-50, 2017 | 79 | 2017 |
A unique method to produce transgenic embryos in ovine, porcine, feline, bovine and equine species F Pereyra-Bonnet, R Fernández-Martín, R Olivera, J Jarazo, G Vichera, ... Reproduction, Fertility and Development 20 (7), 741-749, 2008 | 75 | 2008 |
Equine cloning: in vitro and in vivo development of aggregated embryos A Gambini, J Jarazo, R Olivera, DF Salamone Biology of Reproduction 87 (1), 15, 1-9, 2012 | 63 | 2012 |
Synapse alterations precede neuronal damage and storage pathology in a human cerebral organoid model of CLN3-juvenile neuronal ceroid lipofuscinosis G Gomez-Giro, J Arias-Fuenzalida, J Jarazo, D Zeuschner, M Ali, ... Acta neuropathologica communications 7, 1-19, 2019 | 62 | 2019 |
Parkinson's disease phenotypes in patient neuronal cultures and brain organoids improved by 2‐Hydroxypropyl‐β‐Cyclodextrin treatment J Jarazo, K Barmpa, J Modamio, C Saraiva, S Sabaté‐Soler, I Rosety, ... Movement Disorders 37 (1), 80-94, 2022 | 57 | 2022 |
State of the art: stem cells in equine regenerative medicine MJ Lopez, J Jarazo Equine veterinary journal 47 (2), 145-154, 2015 | 56 | 2015 |
Mitochondrial and clearance impairment in p. D620N VPS35 patient‐derived neurons Z Hanss, SB Larsen, P Antony, P Mencke, F Massart, J Jarazo, ... Movement Disorders 36 (3), 704-715, 2021 | 53 | 2021 |
Impaired mitochondrial–endoplasmic reticulum interaction and mitophagy in Miro1-mutant neurons in Parkinson’s disease C Berenguer-Escuder, D Grossmann, P Antony, G Arena, K Wasner, ... Human molecular genetics 29 (8), 1353-1364, 2020 | 48 | 2020 |
Cheetah interspecific SCNT followed by embryo aggregation improves in vitro development but not pluripotent gene expression LN Moro, MI Hiriart, CP Buemo, J Jarazo, A Sestelo, D Veraguas, ... Bioscientifica, 2015 | 43 | 2015 |
The Parkinson’s-disease-associated mutation LRRK2-G2019S alters dopaminergic differentiation dynamics via NR2F1 J Walter, S Bolognin, SK Poovathingal, S Magni, D Gerard, PMA Antony, ... Cell Reports 37 (3), 2021 | 33 | 2021 |
PINK1 deficiency impairs adult neurogenesis of dopaminergic neurons SJ Brown, I Boussaad, J Jarazo, JC Fitzgerald, P Antony, M Keatinge, ... Scientific reports 11 (1), 6617, 2021 | 32 | 2021 |
Tiger, Bengal and domestic cat embryos produced by homospecific and interspecific zona‐free nuclear transfer LN Moro, J Jarazo, C Buemo, MI Hiriart, A Sestelo, DF Salamone Reproduction in Domestic Animals 50 (5), 849-857, 2015 | 30 | 2015 |
Impaired serine metabolism complements LRRK2-G2019S pathogenicity in PD patients SL Nickels, J Walter, S Bolognin, D Gérard, C Jaeger, X Qing, J Tisserand, ... Parkinsonism & Related Disorders 67, 48-55, 2019 | 21 | 2019 |