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Caitlin C. Zebley
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Developmental plasticity allows outside-in immune responses by resident memory T cells
R Fonseca, LK Beura, CF Quarnstrom, HE Ghoneim, Y Fan, CC Zebley, ...
Nature immunology 21 (4), 412-421, 2020
2372020
Deleting DNMT3A in CAR T cells prevents exhaustion and enhances antitumor activity
B Prinzing, CC Zebley, CT Petersen, Y Fan, AA Anido, Z Yi, P Nguyen, ...
Science translational medicine 13 (620), eabh0272, 2021
1472021
Human memory CD8 T cell effector potential is epigenetically preserved during in vivo homeostasis
HA Abdelsamed, A Moustaki, Y Fan, P Dogra, HE Ghoneim, CC Zebley, ...
Journal of Experimental Medicine 214 (6), 1593-1606, 2017
1402017
Beta cell-specific CD8+ T cells maintain stem cell memory-associated epigenetic programs during type 1 diabetes
HA Abdelsamed, CC Zebley, H Nguyen, RL Rutishauser, Y Fan, ...
Nature immunology 21 (5), 578-587, 2020
752020
CD19-CAR T cells undergo exhaustion DNA methylation programming in patients with acute lymphoblastic leukemia
CC Zebley, C Brown, T Mi, Y Fan, S Alli, S Boi, G Galletti, E Lugli, ...
Cell reports 37 (9), 2021
532021
Rewriting history: epigenetic reprogramming of CD8+ T cell differentiation to enhance immunotherapy
CC Zebley, S Gottschalk, B Youngblood
Trends in immunology 41 (8), 665-675, 2020
472020
Regnase-1 suppresses TCF-1+ precursor exhausted T-cell formation to limit CAR–T-cell responses against ALL
W Zheng, J Wei, CC Zebley, LL Jones, Y Dhungana, YD Wang, J Mavuluri, ...
Blood, The Journal of the American Society of Hematology 138 (2), 122-135, 2021
372021
Epigenetic maintenance of acquired gene expression programs during memory CD8 T cell homeostasis
HA Abdelsamed, CC Zebley, B Youngblood
Frontiers in immunology 9, 329016, 2018
312018
Mechanisms of T cell exhaustion guiding next-generation immunotherapy
CC Zebley, B Youngblood
Trends in cancer 8 (9), 726-734, 2022
252022
Preferential expansion of CD8+ CD19-CAR T cells postinfusion and the role of disease burden on outcome in pediatric B-ALL
AC Talleur, A Qudeimat, JY Métais, D Langfitt, E Mamcarz, JC Crawford, ...
Blood Advances 6 (21), 5737-5749, 2022
222022
Proinflammatory cytokines promote TET2-mediated DNA demethylation during CD8 T cell effector differentiation
CC Zebley, HA Abdelsamed, HE Ghoneim, S Alli, C Brown, D Haydar, ...
Cell reports 37 (2), 2021
172021
Tonic-signaling chimeric antigen receptors drive human regulatory T cell exhaustion
C Lamarche, K Ward-Hartstonge, T Mi, DTS Lin, Q Huang, A Brown, ...
Proceedings of the National Academy of Sciences 120 (14), e2219086120, 2023
152023
Deleting DNMT3A in CAR T cells prevents exhaustion and enhances antitumor activity. Sci. Transl. Med. 13, eabh0272
B Prinzing, CC Zebley, CT Petersen, Y Fan, AA Anido, Z Yi, P Nguyen, ...
112021
CAR T cells need a pitstop to win the race
CC Zebley, B Youngblood
Cancer Cell 39 (6), 756-758, 2021
82021
Cellular and molecular waypoints along the path of T cell exhaustion
X Lan, CC Zebley, B Youngblood
Science immunology 8 (87), eadg3868, 2023
62023
De novo DNA methylation programs regulate CAR T-cell exhaustion
CC Zebley, CT Petersen, B Prinzing, M Bell, Y Fan, JC Crawford, H Houke, ...
The Journal of Immunology 204 (1_Supplement), 246.5-246.5, 2020
52020
Human Memory CD8 T Cell Effector Potential Is Epigenetically Preserved During
HA Abdelsamed, A Moustaki, Y Fan, P Dogra, HE Ghoneim, CC Zebley
Vivo, 0
5
Defining the molecular hallmarks of T-cell memory
CC Zebley, RS Akondy, BA Youngblood, HT Kissick
Cold Spring Harbor Perspectives in Biology 14 (3), a037804, 2022
42022
In vitro homeostatic proliferation of human CD8 T cells
HA Abdelsamed, CC Zebley, B Youngblood
Bio-protocol 7 (22), e2619-e2619, 2017
42017
HIV-Specific CD8 T cells from elite controllers have an epigenetic imprint that preserves effector functions
AB Frias, RL Rutishauser, AA Sharma, T Mi, H Abdelsamed, C Zebley, ...
bioRxiv, 2021.09. 28.459512, 2021
22021
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