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Ken-ichi Ogawara
Ken-ichi Ogawara
Kobe Pharmaceutical University
Bestätigte E-Mail-Adresse bei kobepharma-u.ac.jp
Titel
Zitiert von
Zitiert von
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Time-dependent changes in opsonin amount associated on nanoparticles alter their hepatic uptake characteristics
S Nagayama, K Ogawara, Y Fukuoka, K Higaki, T Kimura
International journal of pharmaceutics 342 (1-2), 215-221, 2007
2662007
Skin permeation of propranolol from polymeric film containing terpene enhancers for transdermal use
C Amnuaikit, I Ikeuchi, K Ogawara, K Higaki, T Kimura
International journal of pharmaceutics 289 (1-2), 167-178, 2005
2382005
Pre-coating with serum albumin reduces receptor-mediated hepatic disposition of polystyrene nanosphere: implications for rational design of nanoparticles
K Ogawara, K Furumoto, S Nagayama, K Minato, K Higaki, T Kai, ...
Journal of controlled release 100 (3), 451-455, 2004
2262004
A Novel Strategy to Modify Adenovirus Tropism and Enhance Transgene Delivery to Activated Vascular Endothelial Cells In Vitro and In Vivo
K Ogawara, MG Rots, RJ Kok, HE Moorlag, AM Van Loenen, DKF Meijer, ...
Human gene therapy 15 (5), 433-443, 2004
1762004
Prolongation of residence time of liposome by surface-modification with mixture of hydrophilic polymers
T Shehata, K Ogawara, K Higaki, T Kimura
International journal of pharmaceutics 359 (1-2), 272-279, 2008
1662008
PEG liposomalization of paclitaxel improved its in vivo disposition and anti-tumor efficacy
Y Yoshizawa, Y Kono, K Ogawara, T Kimura, K Higaki
International journal of pharmaceutics 412 (1-2), 132-141, 2011
1612011
Hepatic uptake of polystyrene microspheres in rats: effect of particle size on intrahepatic distribution
K Ogawara, M Yoshida, K Higaki, T Kimura, K Shiraishi, M Nishikawa, ...
Journal of Controlled Release 59 (1), 15-22, 1999
1611999
Molecular pathways of endothelial cell activation for (targeted) pharmacological intervention of chronic inflammatory diseases
JM Kuldo, KI Ogawara, N Werner, SA Ásgeirsdóttir, JAAM Kamps, RJ Kok, ...
Current vascular pharmacology 3 (1), 11-39, 2005
1202005
In vivo anti-tumor effect of PEG liposomal doxorubicin (DOX) in DOX-resistant tumor-bearing mice: Involvement of cytotoxic effect on vascular endothelial cells
K Ogawara, K Un, K Tanaka, K Higaki, T Kimura
Journal of controlled release 133 (1), 4-10, 2009
1162009
Determinants for in vivo anti-tumor effects of PEG liposomal doxorubicin: importance of vascular permeability within tumors
K Ogawara, K Un, K Minato, K Tanaka, K Higaki, T Kimura
International journal of pharmaceutics 359 (1-2), 234-240, 2008
1002008
Albumin-conjugated PEG liposome enhances tumor distribution of liposomal doxorubicin in rats
J Yokoe, S Sakuragi, K Yamamoto, T Teragaki, K Ogawara, K Higaki, ...
International journal of pharmaceutics 353 (1-2), 28-34, 2008
942008
Effect of coupling of albumin onto surface of PEG liposome on its in vivo disposition
K Furumoto, JI Yokoe, K Ogawara, S Amano, M Takaguchi, K Higaki, ...
International journal of pharmaceutics 329 (1-2), 110-116, 2007
932007
Appearance of double peaks in plasma concentration–time profile after oral administration depends on gastric emptying profile and weight function
Y Metsugi, Y Miyaji, K Ogawara, K Higaki, T Kimura
Pharmaceutical research 25, 886-895, 2008
742008
Role of P‐glycoprotein as a secretory mechanism in quinidine absorption from rat small intestine
Y Emi, D Tsunashima, KI Ogawara, K Higaki, T Kimura
Journal of pharmaceutical sciences 87 (3), 295-299, 1998
731998
Fetuin mediates hepatic uptake of negatively charged nanoparticles via scavenger receptor
S Nagayama, K Ogawara, K Minato, Y Fukuoka, Y Takakura, M Hashida, ...
International journal of pharmaceutics 329 (1-2), 192-198, 2007
722007
Hepatic uptake of negatively charged particles in rats: possible involvement of serum proteins in recognition by scavenger receptor
K Furumoto, S Nagayama, K Ogawara, Y Takakura, M Hashida, K Higaki, ...
Journal of controlled release 97 (1), 133-141, 2004
662004
Surface hydrophobicity of particles is not necessarily the most important determinant in their in vivo disposition after intravenous administration in rats
K Ogawara, K Furumoto, Y Takakura, M Hashida, K Higaki, T Kimura
Journal of controlled release 77 (3), 191-198, 2001
632001
Biliary excretion of polystyrene microspheres depends on the type of receptor-mediated uptake in rat liver
K Furumoto, K Ogawara, M Yoshida, Y Takakura, M Hashida, K Higaki, ...
Biochimica et Biophysica Acta (BBA)-General Subjects 1526 (2), 221-226, 2001
582001
Estimation of intradermal disposition kinetics of drugs: II. Factors determining penetration of drugs from viable skin to muscular layer
K Higaki, M Asai, T Suyama, K Nakayama, K Ogawara, T Kimura
International journal of pharmaceutics 239 (1-2), 129-141, 2002
552002
Enhancement of topical delivery of drugs via direct penetration by reducing blood flow rate in skin
K Higaki, K Nakayama, T Suyama, C Amnuaikit, K Ogawara, T Kimura
International journal of pharmaceutics 288 (2), 227-233, 2005
532005
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