Peter van Galen
Peter van Galen
Massachusetts General Hospital and Broad Institute of MIT and Harvard
Verified email at
TitleCited byYear
Stem cell gene expression programs influence clinical outcome in human leukemia
K Eppert, K Takenaka, ER Lechman, L Waldron, B Nilsson, P Van Galen, ...
Nature medicine 17 (9), 1086, 2011
Variable clonal repopulation dynamics influence chemotherapy response in colorectal cancer
A Kreso, CA O'Brien, P Van Galen, OI Gan, F Notta, AMK Brown, K Ng, ...
Science 339 (6119), 543-548, 2013
Self-renewal as a therapeutic target in human colorectal cancer
A Kreso, P Van Galen, NM Pedley, E Lima-Fernandes, C Frelin, T Davis, ...
Nature medicine 20 (1), 29, 2014
The unfolded protein response governs integrity of the haematopoietic stem-cell pool during stress
P van Galen, A Kreso, N Mbong, DG Kent, T Fitzmaurice, JE Chambers, ...
Nature 510 (7504), 268-272, 2014
Attenuation of miR-126 activity expands HSC in vivo without exhaustion
ER Lechman, B Gentner, P Van Galen, A Giustacchini, M Saini, ...
Cell stem cell 11 (6), 799-811, 2012
miR-126 regulates distinct self-renewal outcomes in normal and malignant hematopoietic stem cells
ER Lechman, B Gentner, SWK Ng, EM Schoof, P van Galen, JA Kennedy, ...
Cancer cell 29 (2), 214-228, 2016
Developmental and oncogenic programs in H3K27M gliomas dissected by single-cell RNA-seq
MG Filbin, I Tirosh, V Hovestadt, MKL Shaw, LE Escalante, ...
Science 360 (6386), 331-335, 2018
Adaptive Chromatin Remodeling Drives Glioblastoma Stem Cell Plasticity and Drug Tolerance
BB Liau, C Sievers, LK Donohue, SM Gillespie, WA Flavahan, TE Miller, ...
Cell Stem Cell 20 (2), 233-246. e7, 2017
A multiplexed system for quantitative comparisons of chromatin landscapes
P van Galen, AD Viny, O Ram, RJH Ryan, MJ Cotton, L Donohue, ...
Molecular cell 61 (1), 170-180, 2016
EHMT1 and EHMT2 inhibition induces fetal hemoglobin expression
A Renneville, P Van Galen, MC Canver, M McConkey, JM Krill-Burger, ...
Blood, The Journal of the American Society of Hematology 126 (16), 1930-1939, 2015
Reduced lymphoid lineage priming promotes human hematopoietic stem cell expansion
P van Galen, A Kreso, E Wienholds, E Laurenti, K Eppert, ER Lechman, ...
Cell stem cell 14 (1), 94-106, 2014
Single-cell RNA-seq reveals AML hierarchies relevant to disease progression and immunity
P van Galen, V Hovestadt, MH Wadsworth II, TK Hughes, GK Griffin, ...
Cell 176 (6), 1265-1281. e24, 2019
Dual targeting of oncogenic activation and inflammatory signaling increases therapeutic efficacy in myeloproliferative neoplasms
M Kleppe, R Koche, L Zou, P van Galen, CE Hill, L Dong, S De Groote, ...
Cancer cell 33 (1), 29-43. e7, 2018
Integrated stress response activity marks stem cells in normal hematopoiesis and leukemia
P van Galen, N Mbong, A Kreso, EM Schoof, E Wagenblast, SWK Ng, ...
Cell reports 25 (5), 1109-1117. e5, 2018
Two new routes to make blood: Hematopoietic specification from pluripotent cell lines versus reprogramming of somatic cells
S Singbrant, P van Galen, D Lucas, G Challen, DJ Rossi, GQ Daley
Experimental hematology 43 (9), 756-759, 2015
A novel method for detecting the cellular stemness state in normal and leukemic human hematopoietic cells can predict disease outcome and drug sensitivity
M Yassin, N Aqaqe, AA Yassin, P van Galen, E Kugler, BE Bernstein, ...
Leukemia 33 (8), 2061-2077, 2019
A stemness screen reveals C3orf54/INKA1 as a promoter of human leukemia stem cell latency
KB Kaufmann, L Garcia-Prat, Q Liu, SWK Ng, SI Takayanagi, A Mitchell, ...
Blood, The Journal of the American Society of Hematology 133 (20), 2198-2211, 2019
Mir-126 Governs Human Leukemia Stem Cell Quiescence and Chemotherapy Resistance
ER Lechman, B Gentner, P van Galen, SWK Ng, K Eppert, R Marke, ...
Blood 122 (21), 1647-1647, 2013
Nucleic acid constructs and methods for labeling and detecting nucleosomal DNA modifications
CB Epstein, P Van Galen, BE Bernstein
US Patent 10,479,986, 2019
Single-Cell RNA-Seq Reveals AML Cellular Hierarchies Relevant to Clinical Outcomes and Immunity
P Van Galen, V Hovestadt, II Wadsworth, T Hughes, GK Griffin, JA Verga, ...
Blood 132 (Supplement 1), 542-542, 2018
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