Peter van Galen
Peter van Galen
Brigham and Women's Hospital, Harvard Medical School
Verified email at bwh.harvard.edu - Homepage
Title
Cited by
Cited by
Year
Stem cell gene expression programs influence clinical outcome in human leukemia
K Eppert, K Takenaka, ER Lechman, L Waldron, B Nilsson, P Van Galen, ...
Nature medicine 17 (9), 1086-1093, 2011
8252011
Variable clonal repopulation dynamics influence chemotherapy response in colorectal cancer
A Kreso, CA O'Brien, P Van Galen, OI Gan, F Notta, AMK Brown, K Ng, ...
Science 339 (6119), 543-548, 2013
6472013
Self-renewal as a therapeutic target in human colorectal cancer
A Kreso, P Van Galen, NM Pedley, E Lima-Fernandes, C Frelin, T Davis, ...
Nature medicine 20 (1), 29-36, 2014
3952014
The unfolded protein response governs integrity of the haematopoietic stem-cell pool during stress
P van Galen, A Kreso, N Mbong, DG Kent, T Fitzmaurice, JE Chambers, ...
Nature 510 (7504), 268-272, 2014
2462014
Developmental and oncogenic programs in H3K27M gliomas dissected by single-cell RNA-seq
MG Filbin, I Tirosh, V Hovestadt, MKL Shaw, LE Escalante, ...
Science 360 (6386), 331-335, 2018
1812018
Adaptive Chromatin Remodeling Drives Glioblastoma Stem Cell Plasticity and Drug Tolerance
BB Liau, C Sievers, LK Donohue, SM Gillespie, WA Flavahan, TE Miller, ...
Cell Stem Cell 20 (2), 233-246. e7, 2017
1742017
miR-126 regulates distinct self-renewal outcomes in normal and malignant hematopoietic stem cells
ER Lechman, B Gentner, SWK Ng, EM Schoof, P van Galen, JA Kennedy, ...
Cancer cell 29 (2), 214-228, 2016
1652016
Attenuation of miR-126 activity expands HSC in vivo without exhaustion
ER Lechman, B Gentner, P Van Galen, A Giustacchini, M Saini, ...
Cell stem cell 11 (6), 799-811, 2012
1642012
Single-cell RNA-seq reveals AML hierarchies relevant to disease progression and immunity
P van Galen, V Hovestadt, MH Wadsworth Ii, TK Hughes, GK Griffin, ...
Cell 176 (6), 1265-1281. e24, 2019
1362019
Dual targeting of oncogenic activation and inflammatory signaling increases therapeutic efficacy in myeloproliferative neoplasms
M Kleppe, R Koche, L Zou, P van Galen, CE Hill, L Dong, S De Groote, ...
Cancer cell 33 (1), 29-43. e7, 2018
822018
A multiplexed system for quantitative comparisons of chromatin landscapes
P van Galen, AD Viny, O Ram, RJH Ryan, MJ Cotton, L Donohue, ...
Molecular cell 61 (1), 170-180, 2016
722016
EHMT1 and EHMT2 inhibition induces fetal hemoglobin expression
A Renneville, P Van Galen, MC Canver, M McConkey, JM Krill-Burger, ...
Blood, The Journal of the American Society of Hematology 126 (16), 1930-1939, 2015
672015
Reduced lymphoid lineage priming promotes human hematopoietic stem cell expansion
P van Galen, A Kreso, E Wienholds, E Laurenti, K Eppert, ER Lechman, ...
Cell stem cell 14 (1), 94-106, 2014
552014
Integrated stress response activity marks stem cells in normal hematopoiesis and leukemia
P van Galen, N Mbong, A Kreso, EM Schoof, E Wagenblast, SWK Ng, ...
Cell reports 25 (5), 1109-1117. e5, 2018
302018
A novel method for detecting the cellular stemness state in normal and leukemic human hematopoietic cells can predict disease outcome and drug sensitivity
M Yassin, N Aqaqe, AA Yassin, P van Galen, E Kugler, BE Bernstein, ...
Leukemia 33 (8), 2061-2077, 2019
102019
Two new routes to make blood: Hematopoietic specification from pluripotent cell lines versus reprogramming of somatic cells
S Singbrant, P van Galen, D Lucas, G Challen, DJ Rossi, GQ Daley
Experimental Hematology 43 (9), 756-759, 2015
92015
A stemness screen reveals C3orf54/INKA1 as a promoter of human leukemia stem cell latency
KB Kaufmann, L Garcia-Prat, Q Liu, SWK Ng, SI Takayanagi, A Mitchell, ...
blood 133 (20), 2198-2211, 2019
62019
Chromatin accessibility promotes hematopoietic and leukemia stem cell activity
L Cabal-Hierro, P van Galen, MA Prado, KJ Higby, K Togami, CT Mowery, ...
Nature communications 11 (1), 1-18, 2020
52020
Single-cell lineage analysis reveals genetic and epigenetic interplay in glioblastoma drug resistance
CE Eyler, H Matsunaga, V Hovestadt, SJ Vantine, P van Galen, ...
Genome biology 21 (1), 1-21, 2020
32020
Mir-126 Governs Human Leukemia Stem Cell Quiescence and Chemotherapy Resistance
ER Lechman, B Gentner, P van Galen, SWK Ng, K Eppert, R Marke, ...
Blood 122 (21), 1647-1647, 2013
12013
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