Marc Zapatka
TitleCited byYear
Driver mutations in histone H3. 3 and chromatin remodelling genes in paediatric glioblastoma
J Schwartzentruber, A Korshunov, XY Liu, DTW Jones, E Pfaff, K Jacob, ...
Nature 482 (7384), 226, 2012
14282012
Driver mutations in histone H3. 3 and chromatin remodelling genes in paediatric glioblastoma
J Schwartzentruber, A Korshunov, XY Liu, DTW Jones, E Pfaff, K Jacob, ...
Nature 482 (7384), 226, 2012
14282012
Hotspot Mutations in H3F3A and IDH1 Define Distinct Epigenetic and Biological Subgroups of Glioblastoma
D Sturm, H Witt, V Hovestadt, DA Khuong-Quang, DTW Jones, ...
Cancer cell 22 (4), 425-437, 2012
10652012
Resistance mechanisms for the Bruton's tyrosine kinase inhibitor ibrutinib
JA Woyach, RR Furman, TM Liu, HG Ozer, M Zapatka, AS Ruppert, L Xue, ...
New England Journal of Medicine 370 (24), 2286-2294, 2014
6592014
Dissecting the genomic complexity underlying medulloblastoma
DTW Jones, N Jäger, M Kool, T Zichner, B Hutter, M Sultan, YJ Cho, ...
Nature 488 (7409), 100, 2012
6322012
Genome sequencing of pediatric medulloblastoma links catastrophic DNA rearrangements with TP53 mutations
T Rausch, DTW Jones, M Zapatka, AM Stütz, T Zichner, J Weischenfeldt, ...
Cell 148 (1-2), 59-71, 2012
5802012
Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma
DTW Jones, B Hutter, N Jäger, A Korshunov, M Kool, HJ Warnatz, ...
Nature genetics 45 (8), 927, 2013
4532013
Genome sequencing of SHH medulloblastoma predicts genotype-related response to smoothened inhibition
M Kool, DTW Jones, N Jäger, PA Northcott, TJ Pugh, V Hovestadt, ...
Cancer cell 25 (3), 393-405, 2014
4062014
Reduced H3K27me3 and DNA hypomethylation are major drivers of gene expression in K27M mutant pediatric high-grade gliomas
S Bender, Y Tang, AM Lindroth, V Hovestadt, DTW Jones, M Kool, ...
Cancer cell 24 (5), 660-672, 2013
3522013
Enhancer hijacking activates GFI1 family oncogenes in medulloblastoma
PA Northcott, C Lee, T Zichner, AM Stütz, S Erkek, D Kawauchi, DJH Shih, ...
Nature 511 (7510), 428, 2014
2762014
DNA methylation-based classification of central nervous system tumours
D Capper, DTW Jones, M Sill, V Hovestadt, D Schrimpf, D Sturm, ...
Nature 555 (7697), 469, 2018
2742018
Decoding the regulatory landscape of medulloblastoma using DNA methylation sequencing
V Hovestadt, DTW Jones, S Picelli, W Wang, M Kool, PA Northcott, ...
Nature 510 (7506), 537, 2014
2362014
The whole-genome landscape of medulloblastoma subtypes
PA Northcott, I Buchhalter, AS Morrissy, V Hovestadt, J Weischenfeldt, ...
Nature 547 (7663), 311, 2017
1962017
Atypical teratoid/rhabdoid tumors are comprised of three epigenetic subgroups with distinct enhancer landscapes
PD Johann, S Erkek, M Zapatka, K Kerl, I Buchhalter, V Hovestadt, ...
Cancer cell 29 (3), 379-393, 2016
1782016
The landscape of genomic alterations across childhood cancers
SN Gröbner, BC Worst, J Weischenfeldt, I Buchhalter, K Kleinheinz, ...
Nature 555 (7696), 321, 2018
1712018
Robust molecular subgrouping and copy-number profiling of medulloblastoma from small amounts of archival tumour material using high-density DNA methylation arrays
V Hovestadt, M Remke, M Kool, T Pietsch, PA Northcott, R Fischer, ...
Acta neuropathologica 125 (6), 913-916, 2013
1712013
Active medulloblastoma enhancers reveal subgroup-specific cellular origins
CY Lin, S Erkek, Y Tong, L Yin, AJ Federation, M Zapatka, P Haldipur, ...
Nature 530 (7588), 57, 2016
1612016
Differential clinical significance of individual NKG2D ligands in melanoma: soluble ULBP2 as an indicator of poor prognosis superior to S100B
A Paschen, A Sucker, B Hill, I Moll, M Zapatka, XD Nguyen, GC Sim, ...
Clinical cancer research 15 (16), 5208-5215, 2009
1452009
Somatic CRISPR/Cas9-mediated tumour suppressor disruption enables versatile brain tumour modelling
M Zuckermann, V Hovestadt, CB Knobbe-Thomsen, M Zapatka, ...
Nature communications 6, 7391, 2015
1402015
DNA methylation dynamics during B cell maturation underlie a continuum of disease phenotypes in chronic lymphocytic leukemia
CC Oakes, M Seifert, Y Assenov, L Gu, M Przekopowitz, AS Ruppert, ...
Nature genetics 48 (3), 253, 2016
1382016
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Articles 1–20