Richard S. Lewis
Richard S. Lewis
Professor of Molecular & Cellular Physiology, Stanford University
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Zitiert von
Zitiert von
A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function
S Feske, Y Gwack, M Prakriya, S Srikanth, SH Puppel, B Tanasa, ...
Nature 441 (7090), 179-185, 2006
Calcium oscillations increase the efficiency and specificity of gene expression
RE Dolmetsch, K Xu, RS Lewis
Nature 392 (6679), 933-936, 1998
Differential activation of transcription factors induced by Ca2+ response amplitude and duration
RE Dolmetsch, RS Lewis, CC Goodnow, JI Healy
Nature 386 (6627), 855-858, 1997
Calcium signaling mechanisms in T lymphocytes
RS Lewis
Annual review of immunology 19 (1), 497-521, 2001
STIM1 clusters and activates CRAC channels via direct binding of a cytosolic domain to Orai1
CY Park, PJ Hoover, FM Mullins, P Bachhawat, ED Covington, S Raunser, ...
Cell 136 (5), 876-890, 2009
Store-operated calcium channels
M Prakriya, RS Lewis
Physiological reviews, 2015
Mitogen-regulated Ca2+ current of T lymphocytes is activated by depletion of intracellular Ca2+ stores.
A Zweifach, RS Lewis
Proceedings of the National Academy of Sciences 90 (13), 6295-6299, 1993
Ca2+ store depletion causes STIM1 to accumulate in ER regions closely associated with the plasma membrane
MM Wu, JA Buchanan, RM Luik, RS Lewis
The Journal of cell biology 174 (6), 803-813, 2006
Molecular basis of calcium signaling in lymphocytes: STIM and ORAI
PG Hogan, RS Lewis, A Rao
Annual review of immunology 28, 491-533, 2009
The elementary unit of store-operated Ca2+ entry: local activation of CRAC channels by STIM1 at ER–plasma membrane junctions
RM Luik, MM Wu, JA Buchanan, RS Lewis
The Journal of cell biology 174 (6), 815-825, 2006
Role of membrane potential and hydrogen bonding in the mechanism of translocation of guanidinium-rich peptides into cells
JB Rothbard, TC Jessop, RS Lewis, BA Murray, PA Wender
Journal of the American Chemical Society 126 (31), 9506-9507, 2004
Abnormal calcium handling properties underlie familial hypertrophic cardiomyopathy pathology in patient-specific induced pluripotent stem cells
F Lan, AS Lee, P Liang, V Sanchez-Freire, PK Nguyen, L Wang, L Han, ...
Cell stem cell 12 (1), 101-113, 2013
Oligomerization of STIM1 couples ER calcium depletion to CRAC channel activation
RM Luik, B Wang, M Prakriya, MM Wu, RS Lewis
Nature 454 (7203), 538-542, 2008
Mitochondrial regulation of store-operated calcium signaling in T lymphocytes
M Hoth, CM Fanger, RS Lewis
The Journal of cell biology 137 (3), 633-648, 1997
Potassium and calcium channels in lymphocytes
RS Lewis, MD Cahalan
Annual review of immunology 13 (1), 623-653, 1995
The molecular choreography of a store-operated calcium channel
RS Lewis
Nature 446 (7133), 284-287, 2007
Potentiation and inhibition of Ca2+ release-activated Ca2+ channels by 2-aminoethyldiphenyl borate (2-APB) occurs independently of IP3 receptors
M Prakriya, RS Lewis
The Journal of physiology 536 (Pt 1), 3, 2001
Mitogen-induced oscillations of cytosolic Ca2+ and transmembrane Ca2+ current in human leukemic T cells.
RS Lewis, MD Cahalan
Cell regulation 1 (1), 99-112, 1989
Defects in actin-cap formation in Vav-deficient mice implicate an actin requirement for lymphocyte signal transduction
LJ Holsinger, IA Graef, W Swat, T Chi, DM Bautista, L Davidson, RS Lewis, ...
Current Biology 8 (10), 563-573, 1998
Different nuclear signals are activated by the B cell receptor during positive versus negative signaling
JI Healy, RE Dolmetsch, LA Timmerman, JG Cyster, ML Thomas, ...
Immunity 6 (4), 419-428, 1997
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