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Fan Ye
Fan Ye
Molecular and Cellular Physiology Department, Stanford University
Bestätigte E-Mail-Adresse bei stanford.edu
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An actin network dispatches ciliary GPCRs into extracellular vesicles to modulate signaling
AR Nager, JS Goldstein, V Herranz-Pérez, D Portran, F Ye, ...
Cell 168 (1), 252-263. e14, 2017
3492017
BBSome trains remove activated GPCRs from cilia by enabling passage through the transition zone
F Ye, AR Nager, MV Nachury
Journal of Cell Biology 217 (5), 1847-1868, 2018
2352018
The intraflagellar transport protein IFT27 promotes BBSome exit from cilia through the GTPase ARL6/BBS3
GM Liew, F Ye, AR Nager, JP Murphy, JS Lee, M Aguiar, DK Breslow, ...
Developmental cell 31 (3), 265-278, 2014
2062014
The oral-facial-digital syndrome gene C2CD3 encodes a positive regulator of centriole elongation
C Thauvin-Robinet, JS Lee, E Lopez, V Herranz-Pérez, T Shida, B Franco, ...
Nature genetics 46 (8), 905-911, 2014
1452014
Single molecule imaging reveals a major role for diffusion in the exploration of ciliary space by signaling receptors
F Ye, DK Breslow, EF Koslover, AJ Spakowitz, WJ Nelson, MV Nachury
Elife 2, e00654, 2013
1392013
HURP regulates chromosome congression by modulating kinesin Kif18A function
F Ye, L Tan, Q Yang, Y Xia, LW Deng, M Murata-Hori, YC Liou
Current biology 21 (18), 1584-1591, 2011
572011
NuSAP modulates the dynamics of kinetochore microtubules by attenuating MCAK depolymerisation activity
C Li, Y Zhang, Q Yang, F Ye, SY Sun, ES Chen, YC Liou
Scientific reports 6 (1), 18773, 2016
422016
Chemical structure-guided design of dynapyrazoles, cell-permeable dynein inhibitors with a unique mode of action
JB Steinman, CC Santarossa, RM Miller, LS Yu, AS Serpinskaya, ...
Elife 6, e25174, 2017
302017
PLK1 interacts and phosphorylates Axin that is essential for proper centrosome formation
K Ruan, F Ye, C Li, YC Liou, SC Lin, SY Lin
PloS one 7 (11), e49184, 2012
242012
Cytoplasmic dynein antagonists with improved potency and isoform selectivity
SK See, S Hoogendoorn, AH Chung, F Ye, JB Steinman, T Sakata-Kato, ...
ACS chemical biology 11 (1), 53-60, 2016
202016
An engineered IL-21 with half-life extension enhances anti-tumor immunity as a monotherapy or in combination with PD-1 or TIGIT blockade
H Liu, R Wang, D An, H Liu, F Ye, B Li, J Zhang, P Liu, X Zhang, S Yao, ...
International Immunopharmacology 101, 108307, 2021
112021
Dose-dependent mutual regulation between Wip1 and p53 following UVC irradiation
Y Xia, Q Yang, X Gong, F Ye, YC Liou
The international journal of biochemistry & cell biology 43 (4), 535-544, 2011
112011
Synergism Between IL21 and Anti-PD-1 Combination Therapy is Underpinned by the Coordinated Reprogramming of the Immune Cellular Network in the Tumor Microenvironment
S Wu, H Huang, R Sun, DS Gao, F Ye, J Huang, E Li, A Ni, KGK Lu, ...
Cancer research communications 3 (8), 1460-1472, 2023
12023
Cytokine fusion proteins, and their pharmaceutical compositions and therapeutic applications
Z Zhong, F Ye, M Siegel, J Huang
US Patent 11,692,020, 2023
12023
1104 A safe and highly potent PD-1-IL-2 fusion (AWT020) that decouples the efficacy and toxicity of IL-2 therapy
F Ye, Z Huang, L Cheng, J Huang, S Chen, M Hua, D Huang, E Li, J Jiang, ...
Journal for ImmunoTherapy of Cancer 10 (Suppl 2), 2022
12022
Cytokine fusion proteins and uses thereof
Z Zhong, F Ye, M Siegel, J Huang, E Liao, E Li
US Patent App. 17/253,481, 2021
12021
Interleukin-2 polypeptides and fusion proteins thereof, and their pharmaceutical compositions and therapeutic applications
F Ye, E Liao, E Li, M Siegel, J Huang, Z Zhong
US Patent 11,897,930, 2024
2024
Cytokine fusion proteins, and their pharmaceutical compositions and therapeutic applications
Z Zhong, F Ye, M Siegel, J Huang
US Patent App. 18/346,250, 2023
2023
Abstract LB029: AWT030: a first-in-class bi-functional IL-21 fusion protein selectively activates tumor infiltrated CD8 T cells and suppresses Treg cells
F Ye, J Huang, S Chen, E Li, J Jiang, H Lin, M Hua, D Huang, Z Huang, ...
Cancer Research 83 (8_Supplement), LB029-LB029, 2023
2023
A HIGHLY POTENT ANTI-LAG-3-IL-2C THAT SELECTIVELY TARGETS TUMOR-SPECIFIC CD8 (+) T CELLS
Z Huang, J Huang, F Ye, S Chen, D Huang, M Hua, E Li, J Jiang, H Lin, ...
Journal for ImmunoTherapy of Cancer 10, A1130-A1130, 2022
2022
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