Lukas Simon
Lukas Simon
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Cited by
Cited by
The spliceosome is a therapeutic vulnerability in MYC-driven cancer
TYT Hsu, LM Simon, NJ Neill, R Marcotte, A Sayad, CS Bland, ...
Nature 525 (7569), 384-388, 2015
PAGA: graph abstraction reconciles clustering with trajectory inference through a topology preserving map of single cells
FA Wolf, FK Hamey, M Plass, J Solana, JS Dahlin, B Göttgens, ...
Genome biology 20 (1), 1-9, 2019
Single-cell RNA-seq denoising using a deep count autoencoder
G Eraslan, LM Simon, M Mircea, NS Mueller, FJ Theis
Nature communications 10 (1), 1-14, 2019
A cellular census of human lungs identifies novel cell states in health and in asthma
FAV Braga, G Kar, M Berg, OA Carpaij, K Polanski, LM Simon, S Brouwer, ...
Nature medicine 25 (7), 1153-1163, 2019
Racial differences in human platelet PAR4 reactivity reflect expression of PCTP and miR-376c
LC Edelstein, LM Simon, RT Montoya, M Holinstat, ES Chen, A Bergeron, ...
Nature medicine 19 (12), 1609-1616, 2013
Human platelet microRNA-mRNA networks associated with age and gender revealed by integrated plateletomics
LM Simon, LC Edelstein, S Nagalla, AB Woodley, ES Chen, X Kong, L Ma, ...
Blood, The Journal of the American Society of Hematology 123 (16), e37-e45, 2014
An atlas of the aging lung mapped by single cell transcriptomics and deep tissue proteomics
I Angelidis, LM Simon, IE Fernandez, M Strunz, CH Mayr, FR Greiffo, ...
Nature communications 10 (1), 1-17, 2019
Single cells make big data: New challenges and opportunities in transcriptomics
P Angerer, L Simon, S Tritschler, FA Wolf, D Fischer, FJ Theis
Current Opinion in Systems Biology 4, 85-91, 2017
Common variants in the human platelet PAR4 thrombin receptor alter platelet function and differ by race
LC Edelstein, LM Simon, CR Lindsay, X Kong, R Teruel-Montoya, ...
Blood, The Journal of the American Society of Hematology 124 (23), 3450-3458, 2014
EMT cells increase breast cancer metastasis via paracrine GLI activation in neighbouring tumour cells
D Neelakantan, H Zhou, MUJ Oliphant, X Zhang, LM Simon, DM Henke, ...
Nature communications 8 (1), 1-14, 2017
A paradox of transcriptional and functional innate interferon responses of human intestinal enteroids to enteric virus infection
K Saxena, LM Simon, XL Zeng, SE Blutt, SE Crawford, NP Sastri, ...
Proceedings of the National Academy of Sciences 114 (4), E570-E579, 2017
The Human Lung Cell Atlas: a high-resolution reference map of the human lung in health and disease
HB Schiller, DT Montoro, LM Simon, EL Rawlins, KB Meyer, M Strunz, ...
American journal of respiratory cell and molecular biology 61 (1), 31-41, 2019
IRE1α-XBP1s pathway promotes prostate cancer by activating c-MYC signaling
X Sheng, HZ Nenseth, S Qu, OF Kuzu, T Frahnow, L Simon, S Greene, ...
Nature communications 10 (1), 1-12, 2019
CELF1 is a central node in post-transcriptional regulatory programmes underlying EMT
A Chaudhury, S Cheema, JM Fachini, N Kongchan, G Lu, LM Simon, ...
Nature communications 7 (1), 1-15, 2016
Alveolar regeneration through a Krt8+ transitional stem cell state that persists in human lung fibrosis
M Strunz, LM Simon, M Ansari, JJ Kathiriya, I Angelidis, CH Mayr, ...
Nature communications 11 (1), 1-20, 2020
GATA2/3-TFAP2A/C transcription factor network couples human pluripotent stem cell differentiation to trophectoderm with repression of pluripotency
C Krendl, D Shaposhnikov, V Rishko, C Ori, C Ziegenhain, S Sass, ...
Proceedings of the National Academy of Sciences 114 (45), E9579-E9588, 2017
Integrative multi-omic analysis of human platelet eQTLs reveals alternative start site in Mitofusin 2
LM Simon, ES Chen, LC Edelstein, X Kong, S Bhatlekar, I Rigoutsos, ...
The American Journal of Human Genetics 98 (5), 883-897, 2016
Longitudinal single cell transcriptomics reveals Krt8+ alveolar epithelial progenitors in lung regeneration
M Strunz, LM Simon, M Ansari, LF Mattner, I Angelidis, CH Mayr, ...
BioRxiv, 705244, 2019
Targeting the mevalonate pathway to overcome acquired anti-HER2 treatment resistance in breast cancer
V Sethunath, H Hu, C De Angelis, J Veeraraghavan, L Qin, N Wang, ...
Molecular Cancer Research 17 (11), 2318-2330, 2019
The protease‐activated receptor 4 Ala120Thr variant alters platelet responsiveness to low‐dose thrombin and protease‐activated receptor 4 desensitization, and is blocked by non …
MJ Whitley, DM Henke, A Ghazi, M Nieman, M Stoller, LM Simon, E Chen, ...
Journal of Thrombosis and Haemostasis 16 (12), 2501-2514, 2018
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