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Philipp Leippe
Philipp Leippe
Project Scientist, CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences
Verified email at cemm.oeaw.ac.at
Title
Cited by
Cited by
Year
Orthogonal optical control of a G protein-coupled receptor with a SNAP-tethered photochromic ligand
J Broichhagen, A Damijonaitis, J Levitz, KR Sokol, P Leippe, D Konrad, ...
ACS central science 1 (7), 383-393, 2015
1222015
Synthesis of Photoswitchable Δ9-Tetrahydrocannabinol Derivatives Enables Optical Control of Cannabinoid Receptor 1 Signaling
MV Westphal, MA Schafroth, RC Sarott, MA Imhof, CP Bold, P Leippe, ...
Journal of the American Chemical Society 139 (50), 18206-18212, 2017
1002017
The RESOLUTE consortium: unlocking SLC transporters for drug discovery
G Superti-Furga, D Lackner, T Wiedmer, A Ingles-Prieto, B Barbosa, ...
Nature reviews Drug discovery 19 (7), 429-430, 2020
862020
Oxidative approach enables efficient access to cyclic azobenzenes
MS Maier, K Hüll, M Reynders, BS Matsuura, P Leippe, T Ko, ...
Journal of the American Chemical Society 141 (43), 17295-17304, 2019
762019
Dual optical control and mechanistic insights into photoswitchable group II and III metabotropic glutamate receptors
J Levitz, J Broichhagen, P Leippe, D Konrad, D Trauner, EY Isacoff
Proceedings of the National Academy of Sciences 114 (17), E3546-E3554, 2017
762017
Specificity and speed: tethered photopharmacology
P Leippe, J Koehler Leman, D Trauner
Biochemistry 56 (39), 5214-5220, 2017
492017
An overview of cell-based assay platforms for the solute carrier family of transporters
V Dvorak, T Wiedmer, A Ingles-Prieto, P Altermatt, H Batoulis, F Bärenz, ...
Frontiers in pharmacology 12, 722889, 2021
482021
Photohormones enable optical control of the peroxisome proliferator-activated receptor γ (PPARγ)
K Hinnah, S Willems, J Morstein, J Heering, FWW Hartrampf, ...
Journal of Medicinal Chemistry 63 (19), 10908-10920, 2020
342020
Designing azobenzene-based tools for controlling neurotransmission
P Leippe, JA Frank
Current Opinion in Structural Biology 57, 23-30, 2019
322019
Conditional and reversible activation of class A and BG protein-coupled receptors using tethered pharmacology
T Podewin, J Ast, J Broichhagen, NHF Fine, D Nasteska, P Leippe, ...
ACS Central Science 4 (2), 166-179, 2018
302018
Development of a photoswitchable antagonist of NMDA receptors
FWW Hartrampf, DM Barber, K Gottschling, P Leippe, M Hollmann, ...
Tetrahedron 73 (33), 4905-4912, 2017
292017
Optical control of a delayed rectifier and a two-pore potassium channel with a photoswitchable bupivacaine
P Leippe, N Winter, MP Sumser, D Trauner
ACS Chemical Neuroscience 9 (12), 2886-2891, 2018
172018
Platform reagents enable synthesis of ligand-directed covalent probes: study of cannabinoid receptor 2 in live cells
M Kosar, DA Sykes, AEG Viray, RM Vitale, RC Sarott, RL Ganzoni, ...
Journal of the American Chemical Society 145 (28), 15094-15108, 2023
162023
Transformation of receptor tyrosine kinases into glutamate receptors and photoreceptors
P Leippe, J Broichhagen, K Cailliau, A Mougel, M Morel, C Dissous, ...
Angewandte Chemie International Edition 59 (17), 6720-6723, 2020
162020
Engineering of a biosensor for intracellular aspartate
L Hellweg, M Pfeifer, L Chang, M Tarnawski, A Bergner, J Kress, J Hiblot, ...
bioRxiv, 2023.05. 04.537313, 2023
42023
AspSnFR: A genetically encoded biosensor for real-time monitoring of aspartate in live cells
L Hellweg, M Pfeifer, M Tarnawski, S Thing-Teoh, L Chang, A Bergner, ...
Cell chemical biology, 2024
22024
Tethered photopharmacology
P Leippe
lmu, 2018
12018
Advancing drug discovery through assay development: a survey of tool compounds within the human solute carrier superfamily
D Digles, A Ingles-Prieto, V Dvorak, TAM Mocking, U Goldmann, ...
Frontiers in pharmacology 15, 1401599, 2024
2024
The genetic interaction map of the human solute carrier superfamily
G Wolf, P Leippe, S Onstein, U Goldmann, F Frommelt, ST Teoh, E Girardi, ...
bioRxiv, 2024.10. 07.616442, 2024
2024
The solute carrier superfamily interactome
F Frommelt, R Ladurner, U Goldmann, G Wolf, A Ingles-Prieto, ...
bioRxiv, 2024.09. 30.615192, 2024
2024
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