Philipp Leippe
Philipp Leippe
Max-Planck-Institute for Medical Research
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Cited by
Cited by
Orthogonal optical control of a G protein-coupled receptor with a SNAP-tethered photochromic ligand
J Broichhagen, A Damijonaitis, J Levitz, KR Sokol, P Leippe, D Konrad, ...
ACS central science 1 (7), 383-393, 2015
Synthesis of Photoswitchable Δ9-Tetrahydrocannabinol Derivatives Enables Optical Control of Cannabinoid Receptor 1 Signaling
MV Westphal, MA Schafroth, RC Sarott, MA Imhof, CP Bold, P Leippe, ...
Journal of the American Chemical Society 139 (50), 18206-18212, 2017
Dual optical control and mechanistic insights into photoswitchable group II and III metabotropic glutamate receptors
J Levitz, J Broichhagen, P Leippe, D Konrad, D Trauner, EY Isacoff
Proceedings of the National Academy of Sciences 114 (17), E3546-E3554, 2017
The RESOLUTE consortium: unlocking SLC transporters for drug discovery
G Superti-Furga, D Lackner, T Wiedmer, A Ingles-Prieto, B Barbosa, ...
Nature reviews Drug discovery 19 (7), 429-430, 2020
Oxidative approach enables efficient access to cyclic azobenzenes
MS Maier, K Hüll, M Reynders, BS Matsuura, P Leippe, T Ko, ...
Journal of the American Chemical Society 141 (43), 17295-17304, 2019
Specificity and speed: tethered photopharmacology
P Leippe, J Koehler Leman, D Trauner
Biochemistry 56 (39), 5214-5220, 2017
An overview of cell-based assay platforms for the solute carrier family of transporters
V Dvorak, T Wiedmer, A Ingles-Prieto, P Altermatt, H Batoulis, F Bärenz, ...
Frontiers in pharmacology 12, 722889, 2021
Photohormones enable optical control of the peroxisome proliferator-activated receptor γ (PPARγ)
K Hinnah, S Willems, J Morstein, J Heering, FWW Hartrampf, ...
Journal of Medicinal Chemistry 63 (19), 10908-10920, 2020
Designing azobenzene-based tools for controlling neurotransmission
P Leippe, JA Frank
Current Opinion in Structural Biology 57, 23-30, 2019
Conditional and reversible activation of class A and BG protein-coupled receptors using tethered pharmacology
T Podewin, J Ast, J Broichhagen, NHF Fine, D Nasteska, P Leippe, ...
ACS Central Science 4 (2), 166-179, 2018
Development of a photoswitchable antagonist of NMDA receptors
FWW Hartrampf, DM Barber, K Gottschling, P Leippe, M Hollmann, ...
Tetrahedron 73 (33), 4905-4912, 2017
Transformation of receptor tyrosine kinases into glutamate receptors and photoreceptors
P Leippe, J Broichhagen, K Cailliau, A Mougel, M Morel, C Dissous, ...
Angewandte Chemie International Edition 59 (17), 6720-6723, 2020
Optical control of a delayed rectifier and a two-pore potassium channel with a photoswitchable bupivacaine
P Leippe, N Winter, MP Sumser, D Trauner
ACS Chemical Neuroscience 9 (12), 2886-2891, 2018
Platform Reagents Enable Synthesis of Ligand-Directed Covalent Probes: Study of Cannabinoid Receptor 2 in Live Cells
M Kosar, DA Sykes, AEG Viray, RM Vitale, RC Sarott, RL Ganzoni, ...
Journal of the American Chemical Society 145 (28), 15094-15108, 2023
Engineering of a biosensor for intracellular aspartate
L Hellweg, M Pfeifer, L Chang, M Tarnawski, A Bergner, J Kress, J Hiblot, ...
bioRxiv, 2023.05. 04.537313, 2023
Tethered photopharmacology
P Leippe
lmu, 2018
An Overview of Cell-Based Assay Platforms for the Solute Carrier Family of Transporters. Front. Pharmacol. 12: 722889. doi: 10.3389/fphar. 2021.722889
V Dvorak, T Wiedmer, A Ingles-Prieto, P Altermatt, H Batoulis, F Bärenz, ...
Frontiers in Pharmacology| www. frontiersin. org 12, 2021
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