| Rho-kinase inactivation prolongs survival of an intermediate SMA mouse model M Bowerman, A Beauvais, CL Anderson, R Kothary Human molecular genetics 19 (8), 1468-1478, 2010 | 206 | 2010 |
| Glucose metabolism and pancreatic defects in spinal muscular atrophy M Bowerman, KJ Swoboda, JP Michalski, GS Wang, C Reeks, A Beauvais, ... Annals of neurology 72 (2), 256-268, 2012 | 196 | 2012 |
| Systemic peptide-mediated oligonucleotide therapy improves long-term survival in spinal muscular atrophy SM Hammond, G Hazell, F Shabanpoor, AF Saleh, M Bowerman, ... Proceedings of the National Academy of Sciences 113 (39), 10962-10967, 2016 | 191 | 2016 |
| Smn depletion alters profilin II expression and leads to upregulation of the RhoA/ROCK pathway and defects in neuronal integrity M Bowerman, D Shafey, R Kothary Journal of molecular neuroscience 32, 120-131, 2007 | 181 | 2007 |
| SMN, profilin IIa and plastin 3: a link between the deregulation of actin dynamics and SMA pathogenesis M Bowerman, CL Anderson, A Beauvais, PP Boyl, W Witke, R Kothary Molecular and Cellular Neuroscience 42 (1), 66-74, 2009 | 165 | 2009 |
| A critical smn threshold in mice dictates onset of an intermediate spinal muscular atrophy phenotype associated with a distinct neuromuscular junction pathology M Bowerman, LM Murray, A Beauvais, B Pinheiro, R Kothary Neuromuscular Disorders 22 (3), 263-276, 2012 | 153 | 2012 |
| Fasudil improves survival and promotes skeletal muscle development in a mouse model of spinal muscular atrophy M Bowerman, LM Murray, JG Boyer, CL Anderson, R Kothary BMC medicine 10, 1-14, 2012 | 147 | 2012 |
| Therapeutic strategies for spinal muscular atrophy: SMN and beyond M Bowerman, CG Becker, RJ Yáñez-Muñoz, K Ning, MJA Wood, ... Disease models & mechanisms 10 (8), 943-954, 2017 | 132 | 2017 |
| Abnormal fatty acid metabolism is a core component of spinal muscular atrophy MO Deguise, G Baranello, C Mastella, A Beauvais, J Michaud, A Leone, ... Annals of clinical and translational neurology 6 (8), 1519-1532, 2019 | 95 | 2019 |
| Spinal muscular atrophy: antisense oligonucleotide therapy opens the door to an integrated therapeutic landscape MJA Wood, K Talbot, M Bowerman Human molecular genetics 26 (R2), R151-R159, 2017 | 86 | 2017 |
| Defects in pancreatic development and glucose metabolism in SMN-depleted mice independent of canonical spinal muscular atrophy neuromuscular pathology M Bowerman, JP Michalski, A Beauvais, LM Murray, Y DeRepentigny, ... Human molecular genetics 23 (13), 3432-3444, 2014 | 76 | 2014 |
| Neuroimmunity dynamics and the development of therapeutic strategies for amyotrophic lateral sclerosis M Bowerman, T Vincent, F Scamps, FE Perrin, W Camu, C Raoul Frontiers in cellular neuroscience 7, 214, 2013 | 64 | 2013 |
| A SMNΔ7 read-through product confers functionality to the SMNΔ7 protein VB Mattis, M Bowerman, R Kothary, CL Lorson Neuroscience letters 442 (1), 54-58, 2008 | 50 | 2008 |
| Interventions targeting glucocorticoid-Krüppel-like factor 15-branched-chain amino acid signaling improve disease phenotypes in spinal muscular atrophy mice LM Walter, MO Deguise, KE Meijboom, CA Betts, N Ahlskog, ... EBioMedicine 31, 226-242, 2018 | 47 | 2018 |
| ROCK inhibition as a therapy for spinal muscular atrophy: understanding the repercussions on multiple cellular targets E Coque, C Raoul, M Bowerman Frontiers in neuroscience 8, 107786, 2014 | 45 | 2014 |
| Pathogenic commonalities between spinal muscular atrophy and amyotrophic lateral sclerosis: Converging roads to therapeutic development M Bowerman, LM Murray, F Scamps, BL Schneider, R Kothary, C Raoul European journal of medical genetics 61 (11), 685-698, 2018 | 40 | 2018 |
| Tweak regulates astrogliosis, microgliosis and skeletal muscle atrophy in a mouse model of amyotrophic lateral sclerosis M Bowerman, C Salsac, E Coque, É Eiselt, RG Deschaumes, ... Human molecular genetics 24 (12), 3440-3456, 2015 | 31 | 2015 |
| The many faces of SMN: deciphering the function critical to spinal muscular atrophy pathogenesis JG Boyer, M Bowerman, R Kothary Future Neurology 5 (6), 873-890, 2010 | 31 | 2010 |
| The relationship between body composition, fatty acid metabolism and diet in spinal muscular atrophy KS Watson, I Boukhloufi, M Bowerman, SH Parson Brain Sciences 11 (2), 131, 2021 | 23 | 2021 |
| Multi-study proteomic and bioinformatic identification of molecular overlap between amyotrophic lateral sclerosis (ALS) and spinal muscular atrophy (SMA) D Šoltić, M Bowerman, J Stock, HK Shorrock, TH Gillingwater, HR Fuller Brain Sciences 8 (12), 212, 2018 | 17 | 2018 |
Thomas GillingwaterProfessor of Anatomy, University of EdinburghVerified email at ed.ac.uk
